Merchant, Gabrielle R.Roeoesli, ChristofNiesten, Marlien E. F.Hamade, Mohamad A.Lee, Daniel J.McKinnon, Melissa L.Ulku, Cagatay H.2024-02-232024-02-2320151531-71291537-4505https://hdl.handle.net/20.500.12452/17803Hypothesis: Power reflectance (PR) measurements in ears with superior canal dehiscence (SCD) have a characteristic pattern, the detection of which can assist in diagnosis. Background: The aim of this study was to determine whether PR coupled with a novel detection algorithm can perform well as a fast, noninvasive, and easy screening test for SCD. The screening test aimed to determine whether patients with various vestibular and/or auditory symptom(s) should be further considered for more expensive and invasive tests that better define the diagnosis of SCD (and other third-window lesions). Methods: Power reflectance was measured in patients diagnosed with SCD by high-resolution computed tomography. The study included 40 ears from 32 patients with varying symptoms (e.g., with and without conductive hearing loss, vestibular symptoms, and abnormal auditory sensations). Results: Power reflectance results were compared to previously published norms and showed that SCD is commonly associated with a PR notch near 1 kHz. An analysis algorithm was designed to detect such notches and to quantify their incidence in affected and normal ears. Various notch detection thresholds yielded sensitivities of 80% to 93%, specificities of 69% to 72%, negative predictive values of 84% to 93%, and a positive predictive value of 67%. Conclusion: This study shows evidence that PR measurements together with the proposed notch-detecting algorithm can be used to quickly and effectively screen patients for third-window lesions such as SCD in the early stages of a diagnostic work up.eninfo:eu-repo/semantics/openAccessAdmittanceEnergy ReflectancePower ReflectanceReflectanceSuperior Canal DehiscenceSuperior Semicircular Canal DehiscenceWideband Acoustic ImmittanceArticle361172177250762272-s2.0-84919479052Q1WOS:000346368200033Q2