Sadic, Cagla CelikkolBilgic, AyhanKilinc, IbrahimOflaz, Mehmet BurhanBaysal, Tamer2024-02-232024-02-2320210162-32571573-3432https://doi.org/10.1007/s10803-020-04579-0https://hdl.handle.net/20.500.12452/11119This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.eninfo:eu-repo/semantics/closedAccessAutismLeptinGhrelinNeuropeptide YNesfatin-1Early ChildhoodArticle512632643325831362-s2.0-85087048990Q1WOS:000543054000001Q110.1007/s10803-020-04579-0