Ozkan, SolmazAtas, Bulent2024-02-232024-02-2320170030-9982https://hdl.handle.net/20.500.12452/17933Familial Mediterranean Fever (FMF) is an autosomal recessive and autoinflammatory disease, characterized with inflammation of serous membranes such as peritoneum, pleura, synovium with fever and pain. Colchicine is the main treatment of FMF, but 5-10 % of patients are unresponsive to colchicine. We report using anti-interleukin-1 agents anakinra and canakinumab in four colchicine-resistant patients who were successfully treated. Three of the patients were siblings.eninfo:eu-repo/semantics/closedAccessFamilial Mediterranean FeverAnakinraCanakinumabEditorial Material676945947285856012-s2.0-85019177052Q4WOS:000402866300027Q4