Zor, Erhan2024-02-232024-02-2320180039-91401873-3573https://doi.org/10.1016/j.talanta.2018.02.096https://hdl.handle.net/20.500.12452/12630Paper-based sensors open new avenue to produce simple, rapid, inexpensive and single-use analytical devices for a wide application fields involving medical diagnosis, food analysis and environmental monitoring. In this study, a new optical sensing platform for enantioselective recognition of chiral analytes was introduced by using in-situ synthesized silver nanoparticles-embedded transparent nanopaper. To this aim, nanopaper was obtained by environment-friendly approach using bacterial cellulose made of nanofibers and silver nanoparticles were embedded within nanopaper by an in-situ generation method. The chiral recognition capability of AgNPs was operated in both solution phase and nanopaper for the tested enantiomers. AgNPs showed a discriminative sensing response toward D-cysteine with a LOD value of 4.88 mu M. The principle of optical sensing is the selective interaction of the inherently chiral AgNPs with enantiomers causing to aggregation of AgNPs to display a significant colour change from yellow to purple-brown in both aqueous phase and nanopaper. As for practical use, the obtained plasmonic nanopaper was punched into circular pieces and put on wax-printed PET film to produce disposable two-dimensional cuvette which could be inserted in an ordinary spectrophotometer. The enantiomeric percentage of D-cysteine was successfully determined by the fabricated nanopaper-based cuvettes.eninfo:eu-repo/semantics/closedAccessChiral RecognitionSilver NanoparticlesNanopaperPaper-Based SensorCalorimetric SensorArticle184149155296740262-s2.0-85043360702Q1WOS:000432234900021Q110.1016/j.talanta.2018.02.096