Guneser, Mehmet BurakAkbulut, Makbule BilgeEldeniz, Ayce Unverdi2024-02-232024-02-2320160287-4547https://doi.org/10.4012/dmj.2015-159https://hdl.handle.net/20.500.12452/16156The aim of the present study was to compare the antimicrobial effect of sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), a CHX/cetrimide solution (CHX+CTR), octenidine hydrochloride (OCT) and Salvia officinalis plant extract against Enterococcus faecalis. Seventy decoronated single -rooted human teeth were infected and divided into 6 test (n,=10) and 2 control groups (n=5) (negative, sterile samples and positive, infected samples). Following irrigants were then applied to test groups: 2.5% NaOCl, 5.25% NaOCl, CHX, CHX+CTR, S. officinalis extract and OCT. The dentin chips were obtained from inner root canal walls and analyzed by counting the number of colony forming units (CFU). The 2.5% NaOCl, 5.25% NaOCl, CHX and OCT groups presented no bacterial growth (CFU=0). S. officinalis and CHX+CTR groups reduced the number of E. faecalis cells but could not eliminate all. OCT may have potential as an endodontic irrigant in treatment of infected root canals.eninfo:eu-repo/semantics/openAccessCetrimideChlorhexidineEnterococcus FaecalisOctenidine HydrochlorideSalvia OfficinalisArticle355736741277255112-s2.0-84989848315Q1WOS:000388249100005Q410.4012/dmj.2015-159