Kaya, AhmetTuran, ElifOzlurk, MineSavut, BulentKulaksizoglu, MustafaGonulalan, Gulsum2024-02-232024-02-2320141301-2193https://doi.org/10.4274/tjem.2467https://hdl.handle.net/20.500.12452/16440A 67-year-old man was admitted to our hospital because of decreased oral intake and confusion. He had a 2-year history of diabetes mellitus and he had a good glycaemic control with oral antidiabetic drugs (latest HbA1C: 7.2%). Quetiapine was initiated 15 days ago in a psychiatric clinic because of depression. The patient was taken to the intensive care unit with the diagnosis of hyperosmolar nonketotic state and acute renal failure. All the medications were discontinued; intravenous hydration and insulin infusion were started. The relationship between secondgeneration antipsychotics (SGAs) and hyperglycemia is a topic of interest and insulin resistance is commonly accepted as the mechanism for hyperglycemia. Patients receiving SGAs should be followed more closely for metabolic disorders.eninfo:eu-repo/semantics/openAccessQuetiapineHyperglisemic Hyperosmolar StateType 2 DmArticle1841401422-s2.0-84916206470Q4WOS:00021737380000910.4274/tjem.2467