Tasdemir, VolkanGenc, HasanMenges, Nurettin2024-02-232024-02-2320230936-52141437-2096https://doi.org/10.1055/a-2159-9400https://hdl.handle.net/20.500.12452/12829The pyrrolo[1,2-a]quinoxaline skeleton has significant potential for many biological and optical applications. Hence, in this study, unconjugated ynone derivatives were treated with 1,2-diaminoarenes in a gold-catalyzed cyclization to give 2-(1H-pyrrol-1-yl)anilines, which are valuable starting materials, and pyrrolo[1,2-a]quinoxalines by a one-pot and single-step approach. A reaction mechanism for the formation of the pyrrolo[1,2-a]quinoxaline skeleton featuring a key gold carbene intermediate is proposed. On the other hand, the methyl group on the C-2 position of the 2-(1H-pyrrol-1-yl)anilines was oxidized by SeO2 to give the pyrrolo[1,2-a]quinoxaline skeleton, resulting in 14 different pyrrolo[1,2-a]quinoxaline derivatives.eninfo:eu-repo/semantics/closedAccessPyrroloquinoxalinesDiaminoarenesPyrrolylanilinesGold CatalysisCyclizationOxidationArticle2-s2.0-85170850119Q2WOS:00109524230000310.1055/a-2159-9400