Kurtoglu, Muhammet GuzelOzdemir, MehmetKesli, RecepBaysal, Bulent2024-02-232024-02-2320141734-19221896-9151https://doi.org/10.5114/aoms.2012.29216https://hdl.handle.net/20.500.12452/16637Introduction: Clinical samples from 433 patients pre-diagnosed with tuberculosis in Konya, Turkey, were investigated prospectively to compare the GenoType (R) MTBC test (GenoType (R) MTBC) with conventional gold standard culture methods. Material and methods: Lowenstein Jensen (LJ) and Mycobacteria Growth Indicator Tube (MGIT)-960 culture methods and GenoType (R) MTBC were performed together. Results: Mycobacterium tuberculosis (M. tuberculosis) detection rates were 16.2% by culture methods, 15.4% by GenoType (R) MTBC, and 6% by acid-fast bacilli microscopy. The LJ or MGIT-960 with GenoType (R) MTBC detected M. tuberculosis in 12 samples each that were negative according to the other culture method alone. Among 70 M. tuberculosis-positive samples, detection rates were 37% (26/70) by microscopy and 82.8% (58/70) by LJ and MGIT-960, but 95.7% (67/70) by GenoType (R) MTBC. Conclusions: GenoType (R) MTBC may be used as a beneficial adjunct test to culture methods for the detection of M. tuberculosis.eninfo:eu-repo/semantics/openAccessMycobacterium TuberculosisGenotypeCultureArticle102315318249046672-s2.0-84901062606Q2WOS:000336108100017Q210.5114/aoms.2012.29216