Naziroglu, Hayriye NevinDurmaz, MustafaBozkurt, SelahattinDemir, Ayhan SitkiSirit, Abdulkadir2024-02-232024-02-2320120957-4166https://doi.org/10.1016/j.tetasy.2012.01.008https://hdl.handle.net/20.500.12452/12635The asymmetric Michael addition of aldehydes to nitroolefins was investigated using a combination of L-prolinamide derivatives and various acidic additives. (S)-1,1'-Bi-2-naphthol was found to be the most effective co-catalyst and afforded the nitroaldehyde products with excellent yields (up to 95%), enantiomeric excesses (up to 99%) and diastereoselectivity ratios (up to 99:1). (C) 2012 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccess[Keyword Not Available]Application of L-prolinamides as highly efficient organocatalysts for the asymmetric Michael addition of unmodified aldehydes to nitroalkenesArticle2321641692-s2.0-84858280792WOS:000302663700010Q210.1016/j.tetasy.2012.01.008