Mehmetoglu, IdrisKurban, SevilToker, AysunAnnaguer, AliAltunhan, HuseyinErbay, EkremOrs, Rahmi2024-02-232024-02-2320151328-80671442-200Xhttps://doi.org/10.1111/ped.12552https://hdl.handle.net/20.500.12452/14022BackgroundWe investigated oxidized low-density lipoprotein (OxLDL) and ischemia-modified albumin (IMA) in cord blood and neonatal blood of 7-day-old neonates born to pre-eclamptic and normotensive healthy mothers. MethodsThe study was performed on 30 neonates born to pre-eclamptic and 20 neonates born to normotensive mothers. IMA and OxLDL were determined on spectrophotometry and ELISA, respectively. ResultsIMA in cord blood was higher in the pre-eclamptic group as compared with the normotensive group, but the difference between the groups was not significant. IMA in neonate venous blood was significantly higher in the pre-eclamptic group than in the normotensive group (P < 0.001). OxLDL in both cord blood and in neonate venous blood was significantly higher in the pre-eclamptic group compared with the normotensive group (P < 0.001). IMA and OxLDL were significantly decreased after delivery in both groups. ConclusionsSignificantly increased cord blood OxLDL and significantly increased OxLDL and IMA 7days after birth in neonates born to pre-eclamptic mothers might be an indicator of increased oxidative stress in pre-eclampsia.eninfo:eu-repo/semantics/closedAccessCord BloodIschemia-Modified AlbuminNeonate Born To Pre-Eclamptic MotherOxidized Low-Density LipoproteinPre-EclampsiaArticle573422426254443622-s2.0-84933531599Q3WOS:000356974900015Q410.1111/ped.12552