A novel calix[4]arene-based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefins

Vural, UmmuDurmaz, MustafaSirit, Abdulkadir2024-02-232024-02-2320162052-4129https://doi.org/10.1039/c6qo00135ahttps://hdl.handle.net/20.500.12452/12785A new chiral calix[4]arene-based organocatalyst 3 bearing bis-squaramide moieties was designed and synthesized from p-tert-butylcalix[4] arene. This bifunctional squaramide organocatalyst was used in the enantioselective conjugate addition of acetylacetone to beta-nitrostyrenes. The corresponding adducts were obtained in good to excellent yields with high enantioselectivities (up to 94% ee).eninfo:eu-repo/semantics/closedAccess[Keyword Not Available]A novel calix[4]arene-based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefinsArticle367307362-s2.0-84971632028Q1WOS:000377257800014Q110.1039/c6qo00135a