Baltaci, A. K.Gokbudak, H.Baltaci, S. B.Mogulkoc, R.Avunduk, M. C.2024-02-232024-02-2320191052-02951473-7760https://doi.org/10.1080/10520295.2019.1612091https://hdl.handle.net/20.500.12452/13163We investigated how resveratrol affects lipid oxidation during experimental renal ischemia-reperfusion injury in rats. We used 48 adult male rats assigned to five groups: group 1, control; group 2, renal ischemia; group 3, renal ischemia + reperfusion; group 4, resveratrol + renal ischemia; group 5, resveratrol + renal ischemia + reperfusion. Plasma and renal tissue malondialdehyde (MDA), and erythrocyte and renal tissue glutathione (GSH) levels were measured and histologic changes in the renal tissue were examined. Ischemia-reperfusion affected the MDA-GSH balance adversely and caused histopathological changes in the renal tissue of the ischemia and ischemia + reperfusion groups. Resveratrol treatment normalized MDA and GSH levels as well as the histopathology that occurred in the renal tissue of the ischemia and ischemia + reperfusion groups.eninfo:eu-repo/semantics/closedAccessHistopathologyLipid OxidationRatRenal IschemiaReperfusionResveratrolArticle948592599312713152-s2.0-85068565705Q2WOS:000474111500001Q410.1080/10520295.2019.1612091