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Öğe Multicenter Real Life Clinical Outcomes of PDL-1 Tested Patients with Non Small Cell Lung Cancer (NSCLC) in Turkey(Elsevier Science Inc, 2022) Yazici, O.; Gurler, F.; Acar, R.; Gurbuz, M.; Guven, D. C.; Tuylu, T. Basoglu; Araz, M.[Abstract Not Availabe]Öğe Evaluation of the Sheffield score, clinical characteristics, and the therapeutic approach in children with upper gastrointestinal system bleeding(Verduci Publisher, 2022) Yucel, A.OBJECTIVE: Unlike adults, there is no valid and reliable scoring system for upper gastrointestinal system bleeding (UGB) in children. The Sheffield scoring system, which is awaiting confirmation, is the single scoring system which can be predictive for children who require high-risk, endoscopic therapeutic intervention. The aim of this study was to evaluate the efficacy of the Sheffield scoring system, the clinical characteristics of patients, and the treatments applied. PATIENTS AND METHODS: Evaluation was made of a total of 86 children with UGB who underwent esophagogastroduodenoscopy and for whom the Sheffield score was calculated. The decision for therapeutic intervention was made according to the clinical status independently of the score. The demographic data of the patients, clinical symptoms and findings, risk factors, and treatments were examined retrospectively. RESULTS: The Sheffield score was calculated as >8 in 67.4% of the patients and > 8 in 32.6%. Endoscopic hemostatic intervention was applied to 15.1% of the patients. The rate of therapeutic endoscopy was significantly high in the high-score group. In 11 patients with Sheffield score >8, the bleeding was brought under control with octreotide treatment administered before endoscopy and no invasive intervention was applied. The sensitivity and specificity of the Sheffield score were determined to be at a good level in the prediction of the requirement for therapeutic endoscopy and octreotide treatment. CONCLUSIONS: The Sheffield score can reliably predict the need for endoscopic treatment with high sensitivity and specificity. In children with a high score, the need for an invasive intervention can be reduced with the administration of vasoactive treatment before esophagogastroduodenoscopy. The Sheffield score can thus be of guidance in the determination of the need for vasoactive treatment.Öğe The effect of a comprehensive support program on the stress level of mothers in a neonatal intensive care unit(Tehran Univ Medical Sciences, 2022) Goral, Esra; Geckil, EmineBackground & Aim: Parents of neonates hospitalized in the neonatal intensive care unit may experience a high level of stress. Although many approaches were applied to reduce stress, little is known about the effect of a comprehensive support program. This study aims to investigate the effect of a comprehensive supportive program on maternal stress levels in a NICU. Methods & Materials: This is a quasi-experimental study that lasted for about eleven months, 62 mothers whose premature neonates were hospitalized in a NICU in Edirne, Turkey, were selected and assigned into intervention and control groups non-randomly. A comprehensive support program was applied for the mothers in the intervention group, whereas the mothers in the control group received the standard routine care. Data were collected using the Parental Information Form, Newborn Information Form, and Parent Stress Scale in NICU and analyzed using SPSS software. Results: The maternal stress level of the mothers in the intervention group (mean=2.95 +/-.72) was found significantly lower than the control group (mean=3.74 +/-.82) (p=001) in the post-test. Similarly, the average scores obtained by the mothers in the intervention group in the Parent Stress Scale's subcategories of images and sounds, neonates' appearance, and change in parental roles were also found to be significantly lower than that obtained by the mother's in the control group (p=001). Conclusion: A comprehensive support program is significantly effective in reducing maternal stress levels. So, it is highly recommended that nurses use these comprehensive approaches in practice and especially support mothers by facilitating interaction between parents experiencing similar problems.Öğe Effect of whitening mouthrinses on color change, whiteness change, surface roughness, and hardness of stained resin composites(Mosher & Linder, Inc, 2023) Fidan, Muhammet; Tuncdemir, Makbule TugbaPurpose: To evaluate the effect of whitening mouthrinses on the color change, whiteness change, surface roughness, and hardness of stained resin composites after different immersion times. Methods: Three different resin composites (Estelite Sigma Quick, G-Aenial Anterior, Omnichroma) were used to prepare a total of 90 samples (30 samples from each resin composite). The samples were kept in coffee for 12 days, then divided into three subgroups (Control, Crest 3D White, and Listerine Advanced White; n=10 each). Color change (Delta E-00) and whiteness change (Delta WID) were evaluated at time intervals of 0-24 hours (TO-T1), 0-72 hours (TO-T2), and 24-72 hours (T1-T2). Surface roughness and hardness values were evaluated at TO, T1, and T2 after immersion in mouthrinses. Two-way ANOVA (for color and whiteness changes) and generalized linear model (for surface roughness and hardness) were used for data analyses (P< 0.05). Results: Omnichroma had the highest value for color change with Crest 3D White during TO-T1 and TO-T2. Crest 3D White showed better color changes than Listerine Advanced White. In all composites and mouthrinse groups, the highest and lowest values of Delta WID were at TO-T2 and T1-T2, respectively, with the highest value for Omnichroma with Crest 3D White at TO-T2 and the lowest for G-Aenial Anterior with control groups at T1-T2. The highest roughness values were found with the Omnichroma at T2. Whitening mouthrinses significantly increased roughness and decreased hardness compared to baseline.Öğe Genotype, phenotype characteristics and long-term follow-up of patients with Vitamin D Dependent Rickets Type IA (VDDR1a): A nationwide multicentre retrospective cross-sectional study(Karger, 2022) Cayir, Atilla; Demirbilek, Huseyin; Turkyilmaz, Ayberk; Turan, Serap; Bereket, Abdullah; Darendeliler, Feyza; Ozbek, Mehmet Nuri[Abstract Not Availabe]Öğe Survey to Investigate Adherence to Growth Hormone Treatment in Children: The Impact of COVID-19 Pandemic(Karger, 2022) Eren, Erdal; Cetinkaya, Semra; Ongen, Yasemin Denkboy; Tercan, Ummuhan; Darcan, Sukran; Turan, Hande; Aydin, Murat[Abstract Not Availabe]Öğe The Effects of Observing Ostracism and Being the Target of Ostracism on Cognitive Flexibility(Hogrefe Ag-Hogrefe Ag Suisse, 2023) Kavakli, Mehmet; Unal, Gulten[Abstract Not Availabe]Öğe Dental Fluorosis Cases in Turkey(John Wiley & Sons Inc, 2023) Derin, Perihan; Yazici-Karabulut, Benan; Demir-Yetis, Aysegul; Karabulut, Abdullah Izzeddin; Atasoy, Ayse Dilek; Yesilnacar, Mehmet Irfan; Bayhan, Ibrahim[Abstract Not Availabe]Öğe Öğe Night Symbol in Mawl?n?'s Mathnaw?(Anadolu Ilahiyat Akademisi, 2023) Ulupinar, Hamide; Gurer, BetulTime has been among the most fundamental subjects in the history of thought with many aspects such as discovering its truth, making sense of it, and managing it. The night, which is the opposite of the daylight and tells about the dark period, has been given great importance by humanity as it covers half of a person's life and greatly affects the biological and spiritual dimensions of life. Although daytime is a time of light and busyness, it has been seen that night is mentioned more often in the Qur'an, and considered as the time period on which Allah has sworn and a verse of His existence. In the verses, the night is used in the real sense as time to rest, a revelation to the prophets, destruction, separation of wise works from oth-ers, time to hide, worship and walk/leave, and metaphorically in the meanings of dark-ness, heedlessness and cover. This study aims to determine the symbolic meanings of the concept of the night in Mawlana's Mathnawi and to reveal the place of the concept in Is-lamic tradition and Sufi culture. The night has not been the subject of academic studies to the extent necessary. It is seen that existing studies on the night focus on its meanings in the Qur'an, concepts and actions related to the night, the virtue of the blessed nights and its use in hadiths. In the studies on Mawlana, only the night in Mawlana's rubais has been discussed in terms of the method of sayr u suluk (journeying and initiation). Therefore, this study aims to fill the gap in determining the symbolic meanings of night, which is half the time, gained in Mawlana's Mathnawi and the place of these symbols in Islamic tradition. Mawlana mostly used the word night in the real sense in Mathnawi. Night expresses the negative time with the symbols of darkness/darkness of human nature, heedlessness, veil when describing the moment when there is no action, and the positive time with the symbols of taking the way / being on the road / meeting (vuslat) when describing the moment of action when man tries to open the door to the truth. These meanings/symbols and usage patterns that Mawlana attributed to the night in his Mathnawi have been enriched by being inspired by the usage and meaning in the Qur'an, and are explained through symbols such as deepening and traveling in the night / in the moment / in the concept.Öğe Does Pregabalin Affect Renal Functions and Plasma Electrolytes?(Wiley, 2023) Gunay, Ahmet Can; Gormus, Z. Isik Solak; Gunay, Merve Akgul; Koca, Raviye Ozen; Ozdengul, Faik[Abstract Not Availabe]Öğe INEQUALITIES IN ACCESS TO DIABETES TECHNOLOGIES IN CHILDREN BY THE SOCIOECONOMIC LEVELS OF FAMILIES: A MULTICENTER, CROSS-SECTIONAL STUDY(Mary Ann Liebert, Inc, 2023) Karakus, K. E.; Sakarya, S.; Yildirim, R.; Özalkak, S.; Özbek, M.; Yildirim, N.; Delibag, G.[Abstract Not Availabe]Öğe Central Precocious Puberty in Boys; Diagnosis, Treatment and Follow-up: A Nation-Wide Study(Karger, 2023) Gunes, Sevinc Odabasi; Sakar, Merve; Sahin, Nursel Muratoglu; Karaguzel, Gulay; Cimbek, Emine Ayca; Darendeliler, Feyza; Sarban, Ezgi[Abstract Not Availabe]Öğe AN OVERVIEW OF TRADITIONAL HEATING, VENTILATION, AND ILLUMINATION TECHNOLOGIES IN HISTORIC BATHS AND THEIR CONTEMPORARY INSPIRATIONS(College Publishing, 2023) Disli, Gulsen; Atan, IsmailPassive heating, lighting, and ventilation techniques in historic buildings and their sustainability in conjunction with new designs are essential to maintaining a greener, ecological environment. This article describes a framework for identifying and dis-closing the passive survival strategies and resulting solutions applied to historic baths in Anatolia. The aim is to first increase knowledge and awareness of ancient systems and to discuss and examine their contemporary inspirations and considerations of existing and new construction technologies. A total of four baths from the Roman, Byzantine, Principalities and Ottoman periods in Anatolia were selected. Their original heating, lighting, and ventilation systems were determined largely through on-site observations, literature review, and archival sources. The results indicate that in today's modern residential, industrial or commercial buildings, reflections of these ancient technologies and traditional concepts can be observed as the main source of inspiration. They can be seen either in the form of light pipes, underfloor heating systems, or a double-skin facade. The old technologies and solutions of historic baths are mostly sustainable and ecological. Looking back at these historic technologies can inspire further ecological design developments and symbiotic implementation possibilities in new building designs.Öğe Investigation of Some Nutrition-related Neuropeptide Expressions in Hypothalamus Tissues of Offspring Exposed to Maternal Depression and Sertraline Treatment.(Wiley, 2023) Solak, Hatice; Koca, Raviye Ozen; Gunes, Canan Eroglu; Uguz, Faruk; Ak, Mehmet; Sahin, Zafer; Kurar, Ercan[Abstract Not Availabe]Öğe Effects of Mu Opioidergic Receptors on Endoplasmic Reticulum Stress in the Hypothalamus on Rats(Wiley, 2023) Sen, Aysu; Gunes, Canan Eroglu; Caliskan, Zeynep; Erkaya, Zeliha; Dursun, Ebru Nur; Kurar, Ercan; Kutlu, Selim[Abstract Not Availabe]Öğe The correlation between electrocardiographic parameters and mortality in non-cardiac ICU patients(Verduci Publisher, 2023) Erdem, K.; Duman, I.; Erguen, R.; Erguen, D.- OBJECTIVE: This study aimed to determine the correlation between selected electrocardiogram (ECG) parameters (recorded at admission) and mortality in non-cardiac, non-COVID-19 intensive care unit (ICU) patients, and to determine the sensitivity and specÖğe The Effect of Morphine Dependence and Morphine Withdrawal on Neuritin and Some Markers of Neurogenesis in the Rat Hippocampus(Wiley, 2023) Cimen, Yasin Ali; Yildiz, Ibrahim; Gunes, Canan Eroglu; Ozkurkculer, Alpaslan; Kurar, Ercan; Kutlu, Selim[Abstract Not Availabe]Öğe The role of decoy receptor 3 in inflammation and atherosclerosis in patients with chronic kidney disease and renal transplant patients(Soc Espanola Nefrologia Dr Rafael Matesanz, 2023) Uysal, Saliha; Toker, Aysun; Turkmen, Kultigin; Keskin, SuatIntroduction: The cardiovascular risk has been increased in chronic kidney disease associated with chronic inflammation and atherosclerosis. Decoy receptor 3, is a member of the TNF receptor superfamily and associated with inflammation and atherosclerosis. The aim of our study is to determine the relationship, between serum DcR3 levels and inflammatory markers in patients with renal transplantation, those receiving dialysis treatment and cases with chronic renal failure that did not receive replacement therapy, and to evaluate their correlation with USG findings. Material and methods: A total of 150 patients aged between 22-86 years, consisting of 4 groups, namely renal transplantation, dialysis, predialysis chronic kidney disease and control groups, were included in the study. Serum decoy receptor 3, VCAM-1, ICAM-1 and IL-8 measured with ELISA method. Carotid intima-media thickness and presence of carotis arter plaque performed by ultrasound probe, non-invasively. Results: All serum markers were higher in dialysis and pre-dialysis chronic kidney disease groups compared to renal transplant and control groups (p < 0.05). Serum decoy receptor 3 level (median(min-max)) of renal transplant group (0.49 ng/mL (0.19-1.65)) was higher than control group (0.35 ng/mL (0.19-2.22)). There was no difference between patients receiving dialysis (0.89 ng/mL (0.41-4.98)) and patients with pre-dialysis chronic kidney disease (0.71 ng/mL (0.29-1.68)). There was no difference between patient groups in terms of the presence of plaque. Conclusion: Although renal transplantation provides a significant improvement in the inflammatory process, not return completely. Inflammatory process associated with uremic milieu may predispose to atherosclerosis in patients with pre-dialysis chronic kidney disease and hemodialysis patients. (c) 2022 Sociedad Espanola de Nefrologia. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Öğe NONCOVID-19 VIRAL RESPIRATORY INFECTIONS IN CHILDREN WITH CANCER DURING THE COVID-19 PANDEMIC: A MULTICENTER OBSERVATIONAL STUDY(Wiley, 2022) Kebudi, Rejin; Kacar, Dilek; Ozyoruk, Derya; Tugcu, Deniz; Yarali, Nese; Ilhan, Inci; Bahadir, Aysenur[Abstract Not Availabe]
