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    Management of Psoriatic Arthritis: Turkish League Against Rheumatism (TLAR) Expert Opinions
    (2018) Nas, Kemal; Kılıç, Erkan; Kocabaş, Hilal; Bodur, Hatice; Ataman, Şebnem; Ayhan, Figen; Çevik, Remzi; Akgül, Özgür; Akıncı, Ayşen; Altay, Zuhal; Çapkın, Erhan; Dağlı, Abdullah Zübeyir; Duruöz, Tuncay; Gürer, Gülcan; Göğüş, Feride; Garip, Yeşim; Kaçar, Cahit; Kamanlı, Ayhan; Kaptanoğlu, Ece; Kaya, Taciser; Özdemirel, Erhan Ali; Özel, Sumru; Sezer, İlhan; Sunar, İsmihan; Yılmaz, Gürkan
    Objectives: This study aims to establish the first national treatment recommendations by the Turkish League Against Rheumatism (TLAR) for psoriatic arthritis (PsA) based on the current evidence. Materials and methods: A systematic literature review was performed regarding the management of PsA. The TLAR expert committee consisted of 13 rheumatologists and 12 physical medicine and rehabilitation specialists experienced in the treatment and care of patients with PsA from 22 centers. The TLAR recommendations were built on those of European League Against Rheumatism (EULAR) 2015. Levels of evidence and agreement were determined. Results: Recommendations included five overarching principles and 13 recommendations covering therapies for PsA, particularly focusing on musculoskeletal involvement. Level of agreement was greater than eight for each item. Conclusion: This is the first paper that summarizes the recommendations of TLAR as regards the treatment of PsA. We believe that this paper provides Turkish physicians dealing with PsA patients a practical guide in their routine clinical practice.
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    Prevalence of Rheumatoid Arthritis and Spondyloarthritis in Turkey: A Nationwide Study
    (2018) Tuncer, Tiraje; Uğurlu, Hatice; Kaçar, Cahit; Kurtaiş, Yeşim; Kutlay, Şehim; Bütün, Bülent; Gilgil, Erdal; Yalçın, Peyman; Akarırmak, Ülkü; Altan, Lale; Ardıç, Füsun; Ardıçoğlu, Özge; Altay, Zuhal; Cantürk, Ferhan; Cerrahoğlu, Lale; Çevik, Remzi; Demir, Hüseyin; Durmaz, Berrin; Dursun, Nigar; Duruöz, Tuncay; Erdoğan, Canan; Evcik, Deniz; Gürsoy, Savaş; Hizmetli, Sami; Kaptanoğlu, Ece; Kayhan, Önder; Kırnap, Mehmet; Kokino, Siranuş; Kozanoğlu, Erkan; Kuran, Banu; Nas, Kemal; Öncel, Sema; Sindel, Dilşad; Orkun, Sevim; Sarpel, Tunay; Savaş, Serpil; Şendur, Ömer Faruk; Şenel, Kazım; Uğurlu, Hatice; Uzunca, Kaan; Tekeoğlu, İbrahim; Guillemin, Francis
    Objectives: This study aims to estimate the prevalence of rheumatoid arthritis (RA) and spondyloarthritis (SpA) in Turkey using the same telephone questionnaire developed for screening RA and SpA in France and used in Serbia and Lithuania. Material and methods: The study was performed in two steps. In step I, the French questionnaire was translated into Turkish and validated through a group of 200 patients (80 males, 120 females; mean age 44.013.1 years; range, 19 to 75 years) followed up at the rheumatology departments of University Hospitals in Antalya and Ankara. In step II, the validated Turkish questionnaire was administered face-to-face to randomly selected 4,012 subjects (1,670 males, 2,342 females; mean age 41.516.8 years; range, 16 to 97 years) by trained general practitioners across the country, in 25 provinces for case detection. The subjects who were suspected of having RA or SpA in accordance with the questionnaire were invited to the nearest university hospital for rheumatologic examination in order to confirm the diagnosis. Results: In step II, a total of 25 subjects (2 males, 23 females) were diagnosed as RA. The standardized RA prevalence for the general population of Turkey was calculated as 0.56% (95% confidence interval [CI]; 0.33-0.79), 0.10% (95% CI; -0.05-0.25) for males and 0.89% (95% CI; 0.51-1.27) for females. A total of 18 subjects (3 males, 15 females) were diagnosed as SpA. The standardized SpA prevalence for the general population of Turkey was 0.46% (95% CI; 0.25-0.67), 0.17% (95% CI; -0.03-0.37) for males and 0.65% (95% CI; 0.32-0.98) for females. The prevalence of RA was highest in the Northern region (2.00%) and the prevalence of SpA was highest in the Central region (1.49%). Conclusion: The prevalences of RA and SpA in Turkey are close to each other and there are significant inter-regional variations in prevalences of both RA and SpA.
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    Turkish League Against Rheumatism Consensus Report: Recommendations For Management of Axial Spondyloarthritis
    (2018) Bodur, Hatice; Yurdakul, Fatma Gül; Ataman, Şebnem; Garip, Yeşim; Nas, Kemal; Ayhan, Fikriye Figen; Kocabaş, Hilal; Akgül, Özgür; Akıncı, Ayşen; Altay, Zuhal; Birtane, Murat; Soy Budayıcı, Derya; Çapkın, Erhan; Çevik, Remzi; Duruöz, Tuncay; Gürer, Gülcan; Kaçar, Cahit; Kamanlı, Ayhan; Kaptanoğlu, Ece; Kaya, Taciser; Kuru, Ömer; Alkan Melikoğlu, Meltem; Özdemirel, Erhan; Özel, Sumru; Rezvani, Aylin; Sezer, İlhan; Sunar, İsmihan; Yılmaz, Gürkan
    Objectives: This study aims to update 2011 Turkish League Against Rheumatism SpondyloArthritis Recommendations, and to compose a national expert opinion on management of axial spondyloarthritis under guidance of current guidelines, and implantation and dissemination of these international guidelines into our clinical practice. Materials and methods: A scientific committee of 28 experts consisting of 14 rheumatologists and 14 physical medicine and rehabilitation specialists (one of them also has an immunology PhD) was formed. The recommendations, systematic reviews, and meta-analyses including pharmacologic and non-pharmacologic treatment were scrutinized paying special attention with convenient key words. The draft of Turkish League Against Rheumatism opinion whose roof consisted of international treatment recommendations, particularly the Assessment of SpondyloArthritis International Society/European League Against Rheumatism recommendations was composed. Assessment of level of agreement with opinions by task force members was established through the Delphi technique. Voting using a numerical rating scale assessed the strength of each recommendation. Results: Panel compromised on five basic principles and 13 recommendations including pharmacological and nonpharmacological methods. All of the recommendations had adequate strength. Conclusion: Turkish League Against Rheumatism expert opinion for the management of axial spondyloArthritis was developed based on scientific evidence. These recommendations will be updated regularly in accordance with current developments.