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Öğe Associations Between Doppler Internal Jugular Vein Blood Flow and Transverse Sinus Stasis Detected by Magnetic Resonance Imaging(Wiley, 2021) Ilhan, Zeki; Acikgozoglu, Saim; Demir, OrhanObjectives This study aimed to compare the estimated internal jugular vein (IJV) volume flow with Doppler ultrasound in patients with slow flow in the transverse sinuses and normal transverse sinuses on brain magnetic resonance imaging (MRI). Methods Eighty patients between the ages of 18 and 80 years who did not have any signs of sinus vein thrombosis on brain MRI were included. On MRI, cases with hyperintensity due to a signal void loss in the transverse sinuses in coronal fluid attenuation inversion recovery sequences were included in the slow-flow group. The presence of sinus thrombosis was excluded with other MRI pulse sequences and clinical findings. The participants were divided into 2 groups as having normal and slow flow according to MRI findings. Then bilateral IJV volume flow measurements were made by Doppler ultrasound. Bilateral volume flow was estimated by time-averaged blood flow velocities sampled in the center of the IJV, and IJV cross-sectional areas were measured. We defined the dominant IJV as the one having the higher estimated volume flow of the 2 sides. Results Total estimated IJV blood flow was lower (P < .001) in patients with slow flow on MRI (546 mL/min) compared to those without (768 mL/min). A similar finding was seen for the nondominant IJV. In a receiver operating characteristic analysis, the cutoff value for the total estimated IJV volume flow was determined to be 590 mL/min, and the cutoff value for nondominant estimated IJV volume flow was determined to be 202 mL/min to distinguish between the groups. Conclusions Low estimated volume blood flow in the IJV is associated with MRI evidence of stasis in the ipsilateral transverse sinus.Öğe Is perinatal arterial ischemic stroke common?(Springer, 2020) Caksen, Huseyin; Koseoglu, Fatma Tuba; Guven, Ahmet Sami; Altunhan, Huseyin; Acikgozoglu, Saim[Abstract Not Availabe]Öğe Non-Invasive Evaluation of Liver Fibrosis Using Real-Time Elastography and Comparison of Intercostal and Subcostal Approaches(Modestum Ltd, 2015) Uslu, Abdulaziz; Batur, Abdussamet; Biyik, Murat; Acikgozoglu, SaimIn patients with chronic liver diseases, the identification of significant fibrosis is of special interest, because the presence of fibrosis is an important parameter for the estimation prognosis, for survelliance and for treatment decisions in patients with Chronic Liver Diseases. Although percutaneous liver biopsy is the gold standart method for assessing liver fibrosis, it has some limitations including its invasive nature, inconvenience, sampling errors, inadequate specimen size and interobserver variability in pathology interpretation. Therefore many studies have focused on the evaluation of noninvasive methods for the assessment of liver fibrosis stage. One of these methods is real time elastography which measures tissue elasticity. In the present study, we assessed intercostal and subcostal measurement methods to discriminate between normal and fibrotic liver.Öğe Risk and Prognostic Factors in Perinatal Hemorrhagic Stroke(Wolters Kluwer Medknow Publications, 2021) Caksen, Huseyin; Koseoglu, Fatma Tuba; Guven, Ahmet Sami; Altunhan, Huseyin; Iyisoy, Mehmet Sinan; Acikgozoglu, SaimBackground: Perinatal stroke encompasses a heterogeneous group of focal neurological injuries early in brain development. In this study, we aimed to compare risk and prognostic factors in preterm and term infants with perinatal hemorrhagic stroke (PHS). Patients and Methods: The study includes 66 infants with PHS. The infants were evaluated for demographic characteristics, fetal and maternal risk factors, perinatal events, clinical and neuroimaging findings, complications, and sequales. Results: Of 66 infants with PHS, 44 (66.70%) were preterm and 22 (33.30%) were term infants. Primiparity, mucosal bleeding, and multiple lobes involvement were more common in term infants than preterm infants (P < 0.05); however, respiratory insufficiency, neonatal sepsis, perinatal asphyxia, respiratory distress syndrome, use of invasive mechanical ventilation, use of noninvasive mechanical ventilation, and prolonged hospitalization were more common in preterm infants than term infants (P < 0.05). Eight (12.12%) infants died during infancy period. Small for gestational age and mucosal bleeding were more common in infants who are dead than those alive (P < 0.05). Forty-two (63.63%) infants were followed. Cerebral palsy and/or epilepsy and/or hydrocephalus were diagnosed in 36 (85.72%) infants during follow-up. Conclusion: Our findings showed that PHS was much more common in preterm infants. Mucosal bleeding and multiple lobes involvement were more common in term infants. PHS has high morbidity and mortality rates. Small for gestational age and mucosal bleeding were more common in infants who are dead.Öğe Risk factors in pediatric cerebral sinovenous thrombosis(Springer, 2023) caksen, Huseyin; Yilmaz, Saniye Yasemin; Guven, Ahmet Sami; Guldibi, Furkan; Acikgozoglu, Saim[Abstract Not Availabe]Öğe Role of Contrast Enhancement and Corrected Attenuation Values of Renal Tumors in Predicting Renal Cell Carcinoma (RCC) Subtypes: Protocol for a Triphasic Multi-Slice Computed Tomography (CT) Procedure(Int Scientific Information Inc, 2017) Ertekin, Ersen; Amasyali, Akin Soner; Erol, Bulent; Acikgozoglu, Saim; Kucukdurmaz, Faruk; Nayman, Alaaddin; Erol, HalukBackground: To distinguish RCC subtypes based on contrast enhancement features of CT images. Material/Methods: In total, 59 lesions from 57 patients were included. All patients underwent multi-slice CT imaging with a triphasic protocol, which included non-contrast, corticomedullary, nephrographic and urographic phases. Contrast enhancement features of renal masses were evaluated in terms of CT attenuation values (AV) and differences in contrast density; the aorta or renal parenchyma were evaluated based on corrected or relative values. Results: Clear cell RCC (ccRCC) showed more intense contrast enhancement than other RCC subtypes. When differentiating ccRCC from other RCC subtypes, a cut-off AV of 86-89 HU, aorta-based corrected AV of 89-95 HU and renal parenchyma-based corrected AV of 87-95 HU showed a diagnostic accuracy of 81-86%, 86-88% and 74-78%, respectively, in the corticomedullary phase. Furthermore, a cutoff of 2.42-2.72 for the relative contrast enhancement ratio, a cutoff of 2.59-2.74 for the aorta-based corrected relative contrast enhancement ratio and a cutoff of 2.63-2.76 for the renal parenchyma based attenuation ratio showed a diagnostic accuracy of 83-88%, 88-90% and 81%, respectively. Conclusions: The most reliable parameters for differentiating ccRCC from other RCC subtypes are aorta-based corrected AV and aorta-based corrected relative contrast enhancement values in the corticomedullary phase.Öğe Role of Contrast Enhancement and Corrected Attenuation Values of Renal Tumors in Predicting Renal Cell Carcinoma (RCC) Subtypes: Protocol for a Triphasic Multi-Slice Computed Tomography (CT) Procedure(Int Scientific Information Inc, 2017) Ertekin, Ersen; Amasyali, Akin Soner; Erol, Bulent; Acikgozoglu, Saim; Kucukdurmaz, Faruk; Nayman, Alaaddin; Erol, HalukBackground: To distinguish RCC subtypes based on contrast enhancement features of CT images. Material/Methods: In total, 59 lesions from 57 patients were included. All patients underwent multi-slice CT imaging with a triphasic protocol, which included non-contrast, corticomedullary, nephrographic and urographic phases. Contrast enhancement features of renal masses were evaluated in terms of CT attenuation values (AV) and differences in contrast density; the aorta or renal parenchyma were evaluated based on corrected or relative values. Results: Clear cell RCC (ccRCC) showed more intense contrast enhancement than other RCC subtypes. When differentiating ccRCC from other RCC subtypes, a cut-off AV of 86-89 HU, aorta-based corrected AV of 89-95 HU and renal parenchyma-based corrected AV of 87-95 HU showed a diagnostic accuracy of 81-86%, 86-88% and 74-78%, respectively, in the corticomedullary phase. Furthermore, a cutoff of 2.42-2.72 for the relative contrast enhancement ratio, a cutoff of 2.59-2.74 for the aorta-based corrected relative contrast enhancement ratio and a cutoff of 2.63-2.76 for the renal parenchyma based attenuation ratio showed a diagnostic accuracy of 83-88%, 88-90% and 81%, respectively. Conclusions: The most reliable parameters for differentiating ccRCC from other RCC subtypes are aorta-based corrected AV and aorta-based corrected relative contrast enhancement values in the corticomedullary phase.
