Yazar "Akin, Duygu" seçeneğine göre listele

Listeleniyor 1 - 7 / 7
  • Küçük Resim Yok
    Öğe
    Assessment of antimutagenic action of Celtis glabrata Steven ex Planch. (Cannabaceae) extracts against base pair exchange and frame shift mutations on Salmonella typhimurium TA98 and TA100 strains by Ames test
    (Taylor & Francis Ltd, 2016) Akin, Duygu; Durak, Yusuf; Uysal, Ahmet; Gunes, Erdogan; Aladag, Mustafa Onur
    Context: Celtis glabrata is used in Turkey for the treatment of various health disorders. Objective: The acetone, chloroform, ethanol, and methanol extracts of C. glabrata leaf, fruit, and seed were investigated to evaluate their antimutagenic activities. Material and methods: The antimutagenicity of these extracts was determined by Ames test against mutagens (4-nitro-O-phenylenediamine, 2-aminofluorene (2-AF), and sodium azide (SA)). The extracts were used at concentrations between 5 and 0.005 mg/plate. Results: The ethanol extracts of leaves exhibited strong antimutagenicity (70%) against 2-AF with S9 at 5 mg/plate on TA98. But methanol (61%, 53%) and acetone (53%, 52%) also revealed strong inhibition rates at concentrations of >= 0.5 mg/plate. Among the extracts, the highest activity (96%) was obtained from acetone extract against SA without S9, followed by chloroform extract (91%) at a dose of 5 mg/plate on TA100 with S9. Ethanol (without S9) and chloroform (with S9) extracts showed strong antimutagenicity at all doses. Exception of chloroform and acetone (without S9), all fruit extracts (with/without S9) manifested strong antimutagenicity at doses of >= 0.5 mg/plate on TA98 strain. Ethanol extracts revealed 68% inhibition against 2-AF on TA98. Acetone and ethanol extracts manifested 84% and 82% inhibition against SA on TA100, respectively. All the extracts of seeds revealed strong inhibition against 2-AF at >= 0.5 mg/plate doses on TA98, but acetone extract showed excellent antimutagenicity (94%). Moreover, the chloroform (74, 73, 63, 54%), acetone (74, 72, 70, 65%) and methanol (74, 67, 63, 61%) extracts of seeds revealed strong antimutagenic activity on TA100 against SA with S9. Discussion and conclusion: This plant may be natural source of antimutagenic agents.
  • Küçük Resim Yok
    Öğe
    A Guideline for Femoral Nerve Block With the Age-Related Formulas Obtained From the Distances Between the Femoral Nerve and Surface Anatomical Landmarks in Fetal Cadavers
    (Soc Chilena Anatomia, 2022) Cihan, Emine; Buyukmumcu, Mustafa; Aydin-Kabakci, Anil Didem; Akin, Duygu; Gungorer, Sule
    The femoral nerve (FN) is used for nerve block in many surgeries and provides effective postoperative analgesics in the pediatric population. However, although there are sufficient anatomical maps and signs for femoral nerve blockades in adults, there is not enough information for the pediatric group. Therefore, in our study, we tried to determine an effective area for safe block blocking with the help of bone structures in order to perform effective blockade in younger age groups. The study was conducted on 60 lower limbs. The exit point of the FN was identified. The measurements were examined in two regards, namely the level of the FN and the relationship of the FN with the surrounding structures. For the right and left sides, all the parameters showed increases with age. A significant relationship was found between all the parameters of the fetal cadavers (p<0.01). It was determined that there was a strong correlation between all parameters related to FN and surrounding bone structures (p<0.01).Sex was not found to be significantly related to the other parameters (p<0.05 Among all the fetal cadavers, high-level division was observed in six limbs (10 %), mid-level division in 33 limbs (55 %), and lower-level division in 21 limbs (35 %). Gestational age-based regression equations from my study showed that the site of the blockage could be effectively performed with the aid of palpable bone structures from the outside without the need for technical assistance.
  • Küçük Resim Yok
    Öğe
    Morphological structure and variations of fetal lateral meniscus: the significance in convenient diagnosis and treatment
    (Springer, 2019) Kabakci, Anil Didem Aydin; Buyukmumcu, Mustafa; Akin, Duygu; Bilge, Onur
    Purpose The aim of this study is to evaluate of morphometry of the lateral meniscus (LM) and determine incidence of the LM shapes. Methods This study was performed on fetal cadaver collection of Anatomy Department of Necmettin Erbakan University. Fifty human fetal cadavers (25 female, 25 male human fetal cadavers) were used in this study. Microdissection was performed. Morphometric measurements were performed. LM were classified into four types and five subtypes. Results In this study, it was identified that all parameters which were measured were found to be increased with gestational ages. Four morphological types and five morphological subtypes were determined. It was found that 12% of the LM were crescent-shaped, 66% of the LM were C-shaped, 14% of the LM were incomplete-disc-shaped, 2% of the LM were disc-shaped, 6% of the LM were variant C-shaped. Conclusions A few studies on fetal meniscal anatomy and its development were performed. Each new study is important for having detailed anatomy and development of the fetal menisci which will have both clinical and anatomical impacts during childhood and adulthood for orthopedic surgeons and anatomists, respectively. The most important results of this study were the detailed objective analysis of the macroscopic fetal growth of LM. It was significantly observed that four morphological types and five morphological subtypes of LM. The results of the present study related with both the observation of morphological development of the fetal meniscal anatomy, and its morphological variants, are important in terms of improving our knowledge, and clinical approach on the description, and the management of the symptomatic lateral discoid meniscus tears in children, adolescents, and adults. The clinical relevance of this study was that this classification of fetal menisci could ameliorate our current understanding of the morphology of lateral meniscus in adult, further.
  • Küçük Resim Yok
    Öğe
    Morphometric analysis of penis development in human fetuses
    (Scientific Publishers India, 2014) Yilmaz, Mehmet Tugrul; Akin, Duygu; Didem, Anil; Kabakci, Aydin; Sahin, Gokalp; Cicekcibasi, Aynur Emine
    In this study, obtaining reference ranges for fetal penis length, penis diameter and femur lengt were aimed. The study was conducted on fifty male fetuses ranging between 14 and 37 weeks of gestational age which was determined using CRL measurement, belonging to Meram Faculty of Medicine, University of Necmettin Erbakan. Data related to penis length, penis diameter and femur length among male fetuses were determined. In 2nd and 3rd trimesters, mean values were calculated 6.62 +/- 3.06 mm and 16.58 +/- 4.82 mm for penis length, 3.39 +/- 1.38 mm and 7.99 +/- 2.07 mm for penis diameter, and 40.72 +/- 9.48 mm and 73.52 +/- 11.58 mm for femur length, respectively. The data were increased by gestational age at rates of % 70 (r(2)=0.69), % 81 (r(2)=0.81), and % 90 (r(2)=0.89), respectively. The relationship between gestational age and all those parameters were statistically meaningful (p<0.01). The reference ranges were determined using the Least Squares regression analysis as follows: Penis length (mm)= 0.763 x Gestational Age (week) - 8.230 Penis diameter (mm)= 0.373 x Gestational Age (week) - 3.947 Femur length (mm)= 2.681 x Gestational Age (week) - 12.079 A normogram belonging to fetal penis was formed which may help to clinicians during ultrasonographic diagnose of genetical anomalies, endocrinological problems and fetal gender determination.
  • Küçük Resim Yok
    Öğe
    Morphometric Analysis of Styloid Process Using Multidetector Computed Tomography
    (Lippincott Williams & Wilkins, 2015) Yilmaz, Mehmet T.; Akin, Duygu; Cicekcibasi, Aynur E.; Kabakci, Anil D. A.; Seker, Muzaffer; Sakarya, Mehmet E.
    Styloid process (SP) is a cylindrical anatomical structure located at the anterior side of stylomastoid foramen. Normally, it is 20 to 25 mm in length and can vary with age and sex. An elongated SP is an unusual source of craniofacial and cervical pain. In this study, the clinical role of morphometric data of SP was discussed. In this study, 64-slice multidetector computed tomography images (Somatom Sensation 64, Siemens, Germany) from Radiology Department's archive of Necmettin Erbakan University were used. The examined images were collected from 100 patients (31 female and 69 male). Length of SP (SPL), SP width (SPW), distance between SP rooths (DBR), SP's angulation, and the distance between SP and internal carotid artery (SP-ICA) were measured. Statistical differences were found regarding to the data of SPL, SPW, DBR, and SP-ICA left between sexes. No statistical significance was detected between right and left side SPL (paired t test; P = 0.989, P > 0.05). SP was observed as mostly type A1 (right %55, left %52). These parameters were also compared with those of previous studies. The present study showed side and sex differences and types of SP. We believe that it was necessary to determine the normal range of values for different populations, and this knowledge will provide guidance to surgeons in the examination of this area.
  • Küçük Resim Yok
    Öğe
    Morphometric Analysis of Suprarenal Glands (Adrenal Glands) with Multislice Computerized Tomography
    (Soc Chilena Anatomia, 2017) Akin, Duygu; Yilmaz, Mehmet Tugrul; Ozbek, Orhan; Ozbiner, Huseyin; Cicekcibasi, Aynur Emine; Buyukmumcu, Mustafa; Kabakci, Anil Didem
    The aim of our study are to determine the shape, vertebrae level, height, volume, corpus medial and lateral branch thicknesses of AG and the distance from some neighboring structures on multidetector computed tomography (MDCT) images and also to determine the relationship between these data and gender, age, height, weight and body mass index (BMI). The study was conducted on a total of 420 MDCT images consisted of 220 male (mean age 63.44 +/- 8.00, 50-81 years), 200 female (mean age 61.23 +/- 7.95, 50-84 years) healthy individuals. Vertebrae level of AG (VLAG), height of AG (HAG), adrenal gland volume (VAG), corpus thickness of AG (CTAG), medial section thickness of AG (MTAG) and lateral section thickness of AG (LTAG) were investigated. In our study, RAG were observed on T12 vertebrae level in 38.19 % of males and 42.5 % of females and LAG were also observed at that level in 39.55 % of the male and 51 % of the female individuals. RAG were observed in all males and 98.5 % of the females and LAG were observed 88.63 % of the males and 94 % of the females Y shaped. VAG were observed lower in males compared to females in age groups and VAG was observed increasing with age in males; decreased in 60-69 age group of females and increased again in 70 and plus age group. The aim of this study is to determine normal ranges of AG sizes and the relationship of each one with sex, age, height, weight and BMI.
  • Küçük Resim Yok
    Öğe
    Morphometric Analysis of the Inferior Vena Cava Related to Lumbar Vertebra and the Aortic Bifurcation on Multidetector Computed Tomography (MDCT)
    (Soc Chilena Anatomia, 2016) Keskinoz, Elif Nedret; Salbacak, Ahmet; Akin, Duygu; Kabakci, Anil Didem Aydin; Yilmaz, Mehmet Tugrul; Cicekcibasi, Aynur Emine; Ozbek, Orhan
    Vascular structures are in greater danger during lumbar surgery. The purpose of this study is to describe the morphology of the inferior vena cava (IVC) related to the lumbar vertebra and aortic bifurcation (AB) and assessing the role of demographic values in these relations to decrease the risk of complications in the surgical interventions. The study was performed on Multidetector Computed Tomography (MDCT) images of 100 male and 100 female cases with an age range from 50 to 84 years. The morphometric values of the IVC obtained from the coronal, sagittal and the axial reformatted images were measured and compared with the demographic values. The distance from the IVC to the 1st lumbar vertebra (L1) and 2nd lumbar vertebra (L2) were measured as (26.5 mm and 18.1 mm) in males and (21.1 mm and 14.2 mm) in females with a high level of significance between genders; the distance from the IVC to the iliocaval confluence (IC), 3rd lumbar vertebra (L3) and 4rd lumbar vertebra (L4) were measured as (6.5 mm, 10.5 mm and 6.9 mm) in males and (4.9 mm, 9.1 mm and 5.5 mm) in females with significance between genders. The level of the IC was detected 46 % of males, 39 % of females at the level of lower third of L4. The vertical distance between the IC and the AB was measured and negative correlation between genders based on age was detected. Demographic values are important to consider the relationship of the IVC, the lumbar vertebra and the AB. The IVC was located further from the lumbar vertebra in males compared to females. Age increase played role in the approaching of the AB and the IC to each other in both gender and the IC to the promontory level in males.