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    Cholesterol granuloma of the jaws: report of two cases
    (Pakistan Medical Assoc, 2014) Alkan, Alper; Etoz, Osman; Candirli, Celal; Ulu, Murat; Dayisoylu, Ezher Hamza
    Cholesterol granuloma (CG) is a foreign body reaction to the deposition and inadequate drainage of cholesterol crystals that are frequently found in association with chronic middle ear diseases but an uncommon entity in maxillary sinuses. The clinical symptoms are non-specific and depend on the localization and extent in each individual case. Bone erosion may be seen in cholesterol granuloma showing expansive growth. The differential diagnosis of CG includes cysts, mucocoeles and neoplasms. Radiological and histopathological findings are essential for diagnosis of CG. In this report it is aimed to introduce two new CG cases with its clinical, histopathological and radiological findings
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    The effects of led-mediated-photobiomodulation therapy on newly formed bone in distraction osteogenesis
    (Bayrakol Medical Publisher, 2020) Akcay, Huseyin; Etoz, Osman A.; Guray, Enis; Avunduk, Mustafa Cihat; Alkan, Alper
    Aim: The purpose of this experimental study was to determine the effects of light emitting diode-mediated-photobiomodulation therapy (LPT) on newly formed bone in mandibular distraction osteogenesis (DO). Materials and Methods: Sixteen adult male New Zealand white rabbits were involved in the study. Osteotomy was done on left mandibular corpus under general anesthesia. Custom-made external distractors were positioned to left mandibles of animals. The latency period was 5 days, then distractors were activated twice a day for 7 days with 0,5mmx2/day frequency. Sixteen rabbits were randomly divided into experimental (n=8) and control (n=8) groups. Animals in the experimental group were exposed to LPT with an energy density of 20mW/cm2 for 21 consecutive days directly over the distraction area starting with the distraction period. DO was performed without further treatment in the control group. After 30 days of consolidation period, the animals were sacrificed and samples were harvested. Bone mineral density (BMD) and bone mineral content (BMC) of bone formed through DO were evaluated using dual-energy x-ray absorptiometry (DEXA) and bone samples were processed for histological investigation. The data were analyzed using the Student t-test and the Mann-Whitney U test (p=0.05).Results: Bone mineral density was higher in the distraction gap of the experimental group (p=0.013). The number of osteoblasts and new bone forming area were significantly greater in the experimental group than the control group (p<0.05). Discussion: The results showed that LPT had a positive effect on the biomodulation of newly formed bone in DO in a rabbit model. Photobiomodulating effects of LLLT and LPT on bone healing seem similar according to the literature and LPT may be a safe and useful alternative for accelerating the treatment process of DO.