Yazar "Alkan, Senay Burcin" seçeneğine göre listele
Listeleniyor 1 - 7 / 7
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Are dietary and serum advanced glycation end-products related to inflammation and oxidation biomarkers in breast cancer patients: a follow-up study(Springer, 2023) Alkan, Senay Burcin; Artac, Mehmet; Aksoy, Faruk; Belviranli, Mehmet Metin; Gurbilek, Mehmet; Cizmecioglu, Hilal Akay; Rakicioglu, NeslisahPurposeThis study is aimed at evaluating the relationship between dietary and serum advanced glycation end-products (AGEs) with serum inflammatory and oxidative stress biomarkers in breast cancer (BC).MethodsA sample of BC patients was followed for 12 months (March 2020-January 2022). Three-day food consumption record and serum samples were taken before surgery (T1), before chemotherapy (T2), at the 6(th) month of chemotherapy (T3), and at the 12(th) month of chemotherapy (T4). Dietary AGE intake was represented by carboxymethyl lysine (dCML). Serum levels of CML, inflammation, and oxidation biomarkers were determined with biochemical blood tests. The results were compared according to human epidermal growth factor receptor-2 (HER2) status.ResultsThirty-two women with BC and 32 age and body mass index-matched healthy women participated. No significant correlation was found between dCML and serum CML, inflammatory or oxidative stress biomarkers at T1, T2, and T4. A weak positive correlation was demonstrated between dCML and serum malondialdehyde levels (rho=0.355, p=0.046) at T3. The serum CML, inflammation, and oxidation biomarker levels of the HER2- group were significantly higher than those of the HER2+ group at T1.ConclusionThis study suggests that there is limited correlation between dCML and serum inflammation and oxidative stress biomarkers in BC patients. Inflammation and oxidative biomarker levels appear to decline with treatment although dietary and serum AGE levels show not a corresponding significant decline. The HER2- subtype appears to be associated with higher dietary and serum AGEs and higher inflammatory and oxidative stress biomarkers.Öğe An assessment of the face on Turkish and African students.(Allied Acad, 2017) Acar, Musa; Alkan, Senay Burcin; Ulusoy, Mahinur; Akkubak, YaseminIntroduction: Calculating the values about the human body dimensions and evaluating them is possible by physical anthropometry. Those values are affected by the factors such as ecological, biological, geographic, racial, gender and age. Method: This study has been carried out on 40 (20 male, 20 female) Turkish and 40 (20 male, 20 female) African students whose ages differed between 18-25 studying in the University of Mevlana and University of Necmettin Erbakan. In the research, the individuals who had been identified with a morphological deformation had a major trauma and plastical or reconstructive surgeries are excluded. The parameters for measurement have been determined as; eye-fissure width (right), eye-fissure width (left), intercanthal distance, outercanthal distance, nose width, nose height, mouth width. Results: Morphometric parameters belonging to both race males and female ears were compared between genders. Right and left tragus-helix and tragus-antihelix distance of Turkish male individuals were founded significantly lower than African male individuals, right and left lobular width and lobular height were founded significantly higher than African male individuals (p<0.05). Left and right ear length of Turkish female individuals, lobular width and left lobular width were founded significantly higher than African Female individuals (p<0.05). Conclusion: Consequently, the values we obtained are important for establishing a referential gap between the individuals of Turkish and African races. Also we are of the opinion that those values will be useful to the anatomists in the anatomical education and to the aesthetic surgeons and dentists.Öğe Dietary Antioxidant Capacity and Serum Inflammatory Biomarkers Levels in Cancer Survivors(Routledge Journals, Taylor & Francis Ltd, 2022) Alkan, Senay Burcin; Artac, Mehmet; Rakicioglu, NeslisahThis study aimed to compare the dietary intake of carotenoids, tocopherols, ascorbic acid, flavonoids, and dietary total antioxidant capacity (dTAC) and to evaluate relationship of dTAC with serum inflammatory biomarkers in patients with gastrointestinal system (GIS) and non-GIS cancer. In total, 104 adult cancer survivors (52 GIS and 52 non-GIS cancer cases) were included. 24-hour dietary recalls were obtained and dTAC was calculated on the basis of oxygen radical absorption capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), total radical-trapping antioxidant parameter (TRAP), ferric reducing antioxidant potential (FRAP), and vitamin C equivalents (VCE). Serum C-reactive protein (CRP) level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) were used as inflammatory biomarkers. Routinely analyzed serum CRP, neutrophil, lymphocyte, and platelet levels every day in hospital biochemistry laboratory were obtained from patients' file. There was no significant difference between patients with GIS and non-GIS cancer in terms of dietary intake of carotenoids, tocopherols, and flavonoids. While there was no significant difference between groups in terms of the mean dietary ORAC, TEAC, and FRAP, the mean TRAP of patients with GIS cancer was significantly higher than patients with non-GIS cancer. Serum inflammatory markers (CRP and NLR) were found to have an inverse relationship with dTAC.Öğe Emotional eating behaviors during the COVID-19 pandemic: A cross-sectional study(Elsevier, 2021) Madali, Berna; Alkan, Senay Burcin; Ors, Elif Didem; Ayranci, Meryem; Taskin, Havvanur; Kara, Hasan HuseyinBackground & aims: The study aimed to evaluate emotional eating tendency of Turkish individuals during COVID-19 pandemic. Methods: The study comprised an online questionnaire and it was conducted from August to September 2020. The survey was distributed through social networks. Results: A total of 1626 adults have been included in the study, aged between 18 and 65 years (69.6% females and 30.4% males). The average BMI of all participants was 24.4 +/- 4.7 kg/m(2), 6% were underweight, and 11.6% were obese. A total of 32.7% of the participants had an increase in appetite and 34.4% had a weight gain. It was found that most of the participants (75.7%) were emotional eaters at different levels. Emotional eating was more common in obese people (43.5%) than normal weight (33.5%) and underweight (18.4%) people. It was examined the increasing food intake according to the BMI, the obese increased the consumption of fresh vegetables, fruits, pastries, and, eggs; underweight increased the consumption of fresh vegetables and fruits, milk and, eggs. As in other countries, a weight gain was observed in the individuals. However, the participants resorted to emotional eating to cope with negative emotions such as depression, anxiety, and stress caused by the pandemic. Conclusions: In this study, it has been provided preliminary data that can be used in future studies to determine the emotional eating behaviors during the COVID-19 pandemic. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.Öğe The Evaluation of Dietary Antioxidant Capacity, Dietary Inflammatory Index and Serum Biomarkers in Breast Cancer: A Prospective Study(Routledge Journals, Taylor & Francis Ltd, 2023) Alkan, Senay Burcin; Artac, Mehmet; Aksoy, Faruk; Belviranli, Mehmet Metin; Gurbilek, Mehmet; Cizmecioglu, Hilal Akay; Rakicioglu, NeslisahDietary antioxidant capacity (dTAC) and dietary inflammatory index (DII) are commonly used to assess nutrition. This prospective study examined dTAC, DII, and serum biomarkers in women with breast cancer (BC). Patients were followed-up before surgery (T-1), before chemotherapy (T-2), at 6(th) (T-3) and 12(th) months of chemotherapy (T-4). Serum tumor necrosis factor alpha, interleukin 1 & beta;, interleukin 6, protein carbonyl, malondialdehyde, total antioxidant capacity (TAC), and total oxidant status levels were analyzed. Dietary antioxidant intake, dTAC, and DII were determined using a three-day dietary record. dTAC was calculated using vitamin C equivalent (VCE), oxygen radical absorption capacity (ORAC), trolox equivalent antioxidant capacity (TEAC), total radical-trapping antioxidant parameter (TRAP), and ferrous ion reducing antioxidant potential (FRAP). This study included 32 women with BC and 32 controls (CG). ORAC, TEAC, TRAP, and FRAP were significantly lower in BC than in CG. During follow-up, only ORAC increased significantly at T-2 compared to T-1. A weak positive correlation was found between dTAC (VCE) and serum TAC levels at T-2 (rho = 0.371, p = 0.036). The relationship between diet and serum biomarkers was not significant. Multicenter prospective studies on different age groups are needed to understand the association between diet and serum biomarkers levels in patients with BC.Öğe The Evaluation of Relationship Between Malnutrition, Quality of Life and Depression in Cancer Patients Treated with Chemotherapy(Marmara Univ, Inst Health Sciences, 2018) Alkan, Senay Burcin; Artac, Mehmet; Rakicioglu, NeslisahObjective: The main aim of the study was to evaluate relationship between malnutrition and quality of life in gastrointestinal (GIS) and non-gastrointestinal (non-GIS) cancer patients treated with chemotherapy. Methods: This study was carried out from March to October 2015. 104 cancer patients (52 GIS and 52 non-GIS cancer cases) participated in the study. The patients aged between 19-64 years-old and treated in a medical oncology clinic. The general characteristics and disease information of the patients were recorded in a questionnaire form. Nutritional status, quality of life, anxiety and depression status were assessed using Patient Generated-Subjective Global Assessment (PG-SGA), European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and Hospital Anxiety and Depression Scale (HADS), respectively. Results: The percentages of malnutrition were found 64.6% and 64.3% in male, and 61.9% and 45.8% in female patients with GIS and non-GIS cancer, respectively. There was negative moderate and significant correlation between PG-SGA score and EORTC QLQ-C30 score (r=-.424, p=0.000). There was positive moderate and significant correlation between PG-SGA score and anxiety score (r=.489, p=0.000) and depression score (r=.514, p=0.000). Conclusion: The nutritional status, quality of life, anxiety and depression level of each patient diagnosed with cancer should be evaluated comprehensive by using appropriate scales. The obtained data will guide the best nutritional therapy and psychological support.Öğe The relationship between nutritional status and handgrip strength in adult cancer patients: a cross-sectional study(Springer, 2018) Alkan, Senay Burcin; Artac, Mehmet; Rakicioglu, NeslisahMalnutrition is a common complication in head, neck and lung cancer patients, particularly in cases of gastrointestinal system (GIS) cancer. Therefore, an assessment of malnutrition is crucial for early nutritional interventions. It was conducted as a cross-sectional study to evaluate nutritional status of adult cancer patients. The nutritional status of 104 cancer patients (52 GIS and 52 non-GIS cancer cases) using a Patient-Generated Subjective Global Assessment (PG-SGA), handgrip strength, certain anthropometric measurements and food consumption in and outside of the hospital were assessed. The percentages of malnutrition were 64.6 and 64.3% in the male patients with and without GIS cancer, respectively. They were 61.9 and 45.8% in the female patients with GIS and without GIS cancer, respectively. However, no significant difference was found between these two groups according to the malnutrition classification, PG-SGA score, handgrip strength and other anthropometric measurements (p > 0.05). The daily energy and protein intakes (per body weight) of the female patients in the hospital were significantly lower than those outside (p < 0.05). In addition, there was a positive moderate and significant relationship between the handgrip strength and lean body mass (r = 0.522, p = 0.000). A negative relationship was observed between the PG-SGA score and the handgrip strength (r = - 0.117, p = 0.071), but it was not statistically significant. Cancer patients could be provided with nutritional education, and arrangements could be made with hospital nutritional services in order to prevent malnutrition.
