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    Effect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzer
    (Taylor & Francis Ltd, 2015) Oltulu, Refik; Satirtav, Gunhal; Altunkaya, Orhan; Bitirgen, Gulfidan; Okka, Mehmet
    Purpose: This observational study aims to investigate the effects of tropicamide (0.5%) on corneal biomechanical properties, with the ocular response analyzer (ORA), in healthy individuals. Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) measurements of 38 (21 female and 17 male) healthy individuals, before and after 30 min of 0.5% tropicamide instillation, were performed by using the ORA. Results: The mean CH, CRF, IOPg and IOPcc measurements of the eyes were 10.2 +/- 1.9 mmHg, 10.3 +/- 2.1 mmHg, 15.7 +/- 3.4 mmHg, 16.4 +/- 3.3 mmHg pre-tropicamide, and 10.4 +/- 1.7 mmHg, 10.3 +/- 2.1 mmHg, 15.3 +/- 3.4 mmHg, 15.8 +/- 2.7 mmHg post-tropicamide, respectively. The differences between the pre- and post-tropicamide measurements of the eyes were insignificant (p = 0.184, p = 0.659, p = 0.294, p = 0.150, respectively; paired t-test). Conclusions: A tropicamide instillation does not lead to significant changes in the corneal biomechanical properties. Therefore, it can be used safely in disease, i.e. in the diagnosis and follow-up ORA as it does not cause any change.
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    Relationship of inferior oblique overaction to macular and subfoveal choroidal thickness
    (Mosby-Elsevier, 2015) Ersan, Ismail; Oltulu, Refik; Altunkaya, Orhan; Satirtav, Gunhal; Arikan, Sedat; Donbaloglu, Meryem; Ozkagnici, Ahmet
    PURPOSE To evaluate the macular and subfoveal choroidal thickness of eyes with inferior oblique muscle overaction (IOOA) using enhanced depth imaging spectral domain optical coherence tomography (EDT SD-OCT). METHODS The measurements of macular and subfoveal choroidal thickness obtained by EDI SD-OCT of patients with IOOA (24 patients) were compared with those of age- and sex-matched controls (25 subjects). RESULTS There were no morphological abnormalities of the macula in patients with IOOA or in control subjects. There were no statistically significant differences in macular and subfoveal choroidal thickness between the eyes with IOOA and the eyes of the control subjects (P > 0.05). When the patients with IOOA were assigned to two distinct groups according to the degree of IOOA, the macular thickness did not differ between groups (P = 0.66), whereas subfoveal choroidal thickness measures were significantly lower in eyes with severe IOOA compared to eyes of the controls (P = 0.01). CONCLUSIONS IOOA has no effect on the morphology and the thickness of the macula. Severe IOOA seems to be related to thinning of subfoveal choroid due to possible external mechanical effect.
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    RELATIONSHIP OF INFERIOR OBLIQUE OVERACTION TO MACULAR AND SUBFOVEAL CHOROIDAL THICKNESS REPLY
    (Mosby-Elsevier, 2016) Ersan, Ismail; Oltulu, Refik; Altunkaya, Orhan; Satirtav, Gunhal; Arikan, Sedat; Donbaloglu, Meryem; Ozkagnici, Ahmet
    [Abstract Not Availabe]