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    COVID-19 Seroprevalance in a University Hospital Health Workers
    (Bilimsel Tip Yayinevi, 2021) Arslan, Gokce Kader; Ozdemir, Mehmet; Kaya, Havva; Feyzioglu, Bahadir; Kepenek Kurt, Esma; Erayman, Ibrahim
    Introduction: Healthcare workers are at the forefront in the Pandemic war against COVID-19 (Coronavirus Disease 2019) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2). In this struggle, they have become high-risk by keeping in close con- tact with patients during their diagnosis, treatment, and follow-up with long working hours. The aim of this study was to contribute to epidemiological data of our country by examining the antibody status of our hospital healthcare workers. Materials and Methods: Anti-SARS-CoV-2 IgG/IgM, COVID-19 ELISA kits were studied from sera samples of healthcare workers in Necmettin Erbakan University Meram Medical Faculty Hospital between June 1 and November 30, 2020. Nasopharyngeal swab sam- ples of these persons were also tested with the Real Time Polymerase Chain Reaction (RT-PCR) method. Results: SARS-CoV-2 seroprevalence of 741 healthcare workers included in our study was found to be 17%. Seropositivity was detected in 6.4% (33/515) of the healthcare workers with negative SARS-CoV-2 PCR test and in 3.9% (5/130) of the healthcare workers who did not have PCR test. Among the healthcare workers, the highest seroprevalence was observed in nurses (39.6%) followed by doctors (%23). Conclusion: It was evaluated that SARS-CoV-2 seroprevalence in healthcare workers is higher than in the population. This study shows that occupational exposure is a risk factor. 3.9% seropositivity was found in healthcare workers who never had a test. Considering that these workers have an asymptomatic or subclinical infection, there is a possible risk for nosocomial transmission. Therefore, healthcare professionals should use personal protective equipment and apply hygiene rules correctly and effectively in infectious diseases, especially during pandemic periods, while working in the hospital.
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    Investigation of the Antimicrobial Effect of Different Disinfectants on Alginate Measurement Materials
    (Georg Thieme Verlag Kg, 2023) Guntekin, Neslihan; Arslan, Gokce Kader; Ozdemir, Mehmet; Tuncdemir, Ali Riza
    Objective The impression materials are contaminated with pathogenic microorganisms carried by saliva and blood in the mouth. The aim of this study is to evaluate the antimicrobial activity of 1 and 5.25% sodium hypochlorite (NaClO) and zeta 7 solution, a commercial disinfectant, on alginate and to compare it washing with distilled water. Methods Samples obtained from alginate impressions taken from eight pediatric patients selected in accordance with the inclusion criteria with a size of 1 x 1 cm were subjected to five different disinfection protocols. After samples were vortexed in 3-mL physiological saline, 1-mL volume were inoculated onto brain heart infusion agar and cultured at 37 & DEG;C for 72 hours to determine the number of colony-forming units/mL. Streptococcus mutans , Staphylococcus aureus , Escherichia coli , Candida albicans were used as control strains. The data obtained were statistically evaluated by using analysis of variance and post-hoc tests. The differences were considered statistically significant when p < 0.05. Results All of the disinfectant solutions tested were effective in the disinfection of the impression materials examined. The control group with no treatment and the water and flushing group had a significantly higher bacterial load compared to the other disinfectant-treated groups in terms of bacterial load, and no significant difference has been observed between the disinfectant solutions ( p < 0.05). Simple rinsing of the impressions in sterile water reduced the number of microorganisms but did not decontaminate the impressions. Conclusion Washing with water alone is insufficient for measured disinfection. Although NaClO is an effective disinfectant even at low concentrations, microorganism growth was not observed at 5.25% concentration. It is appropriate to use NaClO at 1 and 5.25% concentrations for impression disinfection.