Yazar "Avunduk, M. C." seçeneğine göre listele

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    Effect of Pinealectomy and Melatonin Supplementation on Metallothionein, Zinc Transport Protein Levels in the Small Intestine Sections of the Rat
    (Wiley, 2017) Unal, O.; Baltaci, A. K.; Mogulkoc, R.; Avunduk, M. C.
    [Abstract Not Availabe]
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    Effect of Resveratrol Application on Lipid Peroxidation in Experimental Renal Ischemia-Reperfusion Injury in Rats
    (Wiley, 2017) Baltaci, A. K.; Gokbudak, H.; Mogulkoc, R.; Avunduk, M. C.; Menevse, E.
    [Abstract Not Availabe]
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    Effects of alpha-tocopherol on gingival expression of inducible nitric oxide synthase in the rats with experimental periodontitis and diabetes
    (Wolters Kluwer Medknow Publications, 2016) Hatipoglu, M.; Alptekin, N. O.; Avunduk, M. C.
    Background: The aim of this study was to investigate effects of -tocopherol and/or insulin on the number of gingival inducible nitric oxide synthase (iNOS) positive cells in rats with experimental periodontitis with or without streptozotocin (STZ)-induced diabetes. Materials and Methods: A total of 60 Sprague-Dawley rats were divided into three groups: Group I: The group without diabetes; Group II: The group with STZ-induced diabetes; Group III: The group with STZ-induced diabetes receiving insulin therapy. All animals received anesthesia, and 3/0 silk suture was inserted around the mandibular molar teeth. All groups were divided into subgroups receiving saline (Groups IA, IIA, IIIA) and -tocopherol injection (Groups IB, IIB, IIIB). After a period of 3 weeks, all rats were sacrificed, and the number of gingival iNOS positive cells was analyzed using image analysis software. Results: Applying -tocopherol suppressed the number of gingival iNOS positive cells in Groups IB, IIB, and IIIB compared to application of saline (Groups IA, IIA, and IIIA) (P 0.05). Numbers of gingival iNOS positive cells were found to be similar in the Groups I and III (P 0.05). Conclusions: Within limitations of the current study, this is the first study one may suggest that -tocopherol may reduce oxidative damage in the gingiva of the rats with periodontitis with or without STZ-induced diabetes and increase effects of insulin.
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    The effects of resveratrol administration on lipid oxidation in experimental renal ischemia-reperfusion injury in rats
    (Taylor & Francis Ltd, 2019) Baltaci, A. K.; Gokbudak, H.; Baltaci, S. B.; Mogulkoc, R.; Avunduk, M. C.
    We investigated how resveratrol affects lipid oxidation during experimental renal ischemia-reperfusion injury in rats. We used 48 adult male rats assigned to five groups: group 1, control; group 2, renal ischemia; group 3, renal ischemia + reperfusion; group 4, resveratrol + renal ischemia; group 5, resveratrol + renal ischemia + reperfusion. Plasma and renal tissue malondialdehyde (MDA), and erythrocyte and renal tissue glutathione (GSH) levels were measured and histologic changes in the renal tissue were examined. Ischemia-reperfusion affected the MDA-GSH balance adversely and caused histopathological changes in the renal tissue of the ischemia and ischemia + reperfusion groups. Resveratrol treatment normalized MDA and GSH levels as well as the histopathology that occurred in the renal tissue of the ischemia and ischemia + reperfusion groups.