Yazar "Aydin, Leyla" seçeneğine göre listele

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    Cognitive Deterioration Following Strength Training in Adolescents
    (Wiley, 2019) Yargic, Melda Pelin; Aydin, Leyla; Erdagi, Kenan; Kiziltan, Erhan
    [Abstract Not Availabe]
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    Determination of Effective Mechanism of Melatonin in Hyperthermic Febrile Convulsion in Rats
    (Karger, 2018) Aydin, Leyla; Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim
    [Abstract Not Availabe]
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    Improved Pinch Force Sense in Adolescent Female Weightlifters
    (Wiley, 2019) Erdagi, Kenan; Yargic, Melda Pelin; Aydin, Leyla
    [Abstract Not Availabe]
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    Role of Melatonin Receptors in Hyperthermia-Induced Acute Seizure Model of Rats
    (Humana Press Inc, 2019) Mogulkoc, Rasim; Baltaci, Abdulkerim Kasim; Aydin, Leyla
    Melatonin is a neurohormone that has anticonvulsant activity in different experimental seizure models including hyperthermic febrile seizure. However, the mechanisms of this effect are not clear at the receptor level. The aim of the study was to determine which melatonin receptors involve in the hyperthermic febrile seizure model. 22-30 days Wistar male rats were used, and in children, it corresponds to 1.5-2 years. Groups were performed as (1) control, (2) ethanol/saline, (3) DMSO, (4) melatonin (MT), (5) MT + luzindole (LUZ), (6) MT + K-185, (7) MT + prazosin (PRZ), (8) MT + LUZ + K-185, (9) MT + LUZ + PRZ, (10) MT + K-185 + PRZ, and (11) MT + LUZ + PRZ + K-185. The hyperthermic febrile seizure pattern was established by keeping the rats in 45 degrees C hot water, and the latency, duration, and severity of seizures were determined in all groups. MT, LUZ, K-185, and PRZ were given 15, 45, 15, and 30 min before the induction of seizure, respectively. It was observed that melatonin shortened the duration of seizure, reduced the severity, and did not affect latency and that these effects were not completely blocked by receptor antagonists when compared with control, ethanol/saline, and DMSO groups. In conclusion, the fact that the anticonvulsant effect of melatonin is not completely blocked by all melatonin receptor antagonists. We can conclude that a multimodal mechanism may be responsible for the effect of melatonin receptors alone on the anticonvulsant effect of melatonin. It will be useful to design new pharmacological studies to make the subject clear.
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    THE USE OF COMPUTER BASED TEST BATTERY FOR THE ASSESSMENT OF COGNITIVE FUNCTIONS IN ELITE-LEVEL STRENGTH TRAINING
    (IEEE, 2019) Yargic, Melda Pelin; Erdagi, Kenan; Aydin, Leyla; Kiziltan, Erhan
    The aim of this study was to propose a standard test battery consisting of necessary tools for measuring and comparing the various aspects of cognitive outcomes. The battery was used to determine whether adolescent women performing regular elite-level strength training differed from their sedentary peers in terms of cognition, and also to determine how a single session of strength training affects cognition in highly trained adolescents. Motor functions, ability of sustaining attention and executive functions of 25 elite female weightlifters and 22 sedentary females were evaluated through finger tapping performance, visual reaction time (VRT) and recognition visual reaction time (R-VRT) data. Weightlifters were tested before and after a training session, sedentary controls were tested only during resting. There was a significant increase in mean complex R-VRT of weightlifters after training (p<0.01). In R-VRT tests, rate of false answers increased significantly after training (p<0.05). Mean VRT of weightlifters (during rest) and sedentary peers were not different in any of the tests (p>0.05). Total number of taps and mean inter-tap intervals did not show any difference in the weightlifter group before and after training, also between weightlifters and sedentary controls (p>0.05). Elite level strength training does not improve cognition in adolescence. Adolescent weightlifters' executive functions are deteriorated following a single training session however, this effect is temporary.