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Öğe Suicide in two patients with epilepsy and cystic degeneration areas of their brains(Romanian Legal Med Soc, 2013) Dogan, Kamil Hakan; Demirci, Serafettin; Baba, Z. Fusun; Buken, BoraSuicide is an important cause of death among patients with epilepsy. In this report, we describe two patients with epilepsy whose brain examinations revealed cystic degeneration areas. The first case was a 42-year-old man who had been treated for epilepsy for five years. It was reported that his epilepsy attacks had increased over the six months prior to his suicide, and that he had severe conflicts with his wife during the last two months. He committed suicide by hanging. An autopsy revealed two cystic degeneration areas on the left temporal lobe, and one cystic degeneration area on the right parietal lobe. The second case was a 30-year-old man who had been receiving epilepsy treatment for 10 years. It was reported that his epilepsy attacks had increased in the four months prior to his suicide, and his wife had left home because of continuous arguments. He committed suicide by drinking rodenticide (aluminum phosphide). An autopsy revealed a cystic degeneration area on the right temporal lobe. Neither of the two cases had a history of head injury, and the cystic areas are evaluated as border zone infarcts due to prolonged hypoxemia caused by recurrent status epilepticus attacks. In conclusion, in case of the determination of the cystic degeneration areas in patients with epilepsy in computed tomography or magnetic resonance imaging examinations, it will be beneficial to follow these patients in terms of epileptic attacks and psychiatric defects.Öğe Systemic treatment with alpha-tocopherol and/or sodium selenite decreases the progression of experimental periodontitis(Springer Heidelberg, 2021) Bas, Nurgul; Kayar, Nezahat Arzu; Baba, Z. Fusun; Avunduk, Mustafa Cihat; Haliloglu, Seyfullah; Alptekin, Nilgun OzlemObjective To investigate the effects of sodium selenite (Se) and/or alpha-tocopherol (alpha T) applications on the alveolar bone loss (ABL), the number of gingival collagen fibers, inducible nitric oxide synthase (iNOS)+ and CD95+ cell numbers, and serum cytokine concentrations in experimental periodontitis in rats. Materials and methods Forty Sprague Dawley rats were divided into four groups of ten as follows: group A: Se group, group B: alpha T group, group C: Se and alpha T combined group, and group D: control group (intraperitoneal (IP) saline injection applied). Using the image analysis method in the connective tissue under the connective epithelium, the numbers of iNOS, CD95 positive cells, and collagen fibers were counted. ELISA kits were used to test the concentrations of serum interleukin (IL)-1 beta, IL-6, and IL-4. Results The combination of Se and alpha T (group C) suppressed ABL compared with the control group (group D) (P< 0.05). In group A (Se), the number of iNOS+ cells was smaller than in group D (P< 0.05). Conclusion Se has been concluded to inhibit inflammation of the gum due to iNOS. Se and alpha T can have a remarkable important role in preventing alveolar bone loss, and particularly in combination.