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Öğe Effects of Isotretinoin on the Platelet Counts and the Mean Platelet Volume in Patients with Acne Vulgaris(Hindawi Ltd, 2014) Ataseven, Arzu; Bilgin, Aynur UgurAim. The aim of this study was to evaluate the platelet counts and the mean platelet volume in patients who received isotretinoin for the treatment of acne vulgaris. Method. A total of 110 patients were included in this retrospective study. Complete blood count parameters were recorded prior to and three-months following the treatment. Results. Both platelet counts and the mean platelet volume were significantly decreased following the treatment. No significant differences were noted on the levels of hemoglobin, hematocrit, and white blood cell count. Conclusion. Platelet counts and mean platelet volume significantly decreased following isotretinoin treatment. Since the decrease of platelet counts and the mean platelet volume was seen concomitantly, it is concluded that the effect of isotretinoin was through the suppression of bone marrow.Öğe Intramesenteric Steroid Treatment for Steroid-Refractory Gastrointestinal Graft Versus Host Disease(Galenos Yayincilik, 2012) Bilgin, Aynur Ugur; Topcuoglu, Pervin; Sancak, Tanzer; Konuk, Nahide; Arat, MutluCurrently, steroid-refractory severe gastrointestinal (GI) graft versus host disease (GVHD) is among the most important complications of allogeneic transplantation, and as yet there is no standard approach to its treatment. Herein we report two cases with steroid-refractory GI GVHD that received intramesenteric steroid treatment. In both cases the frequency and volume of diarrhea resolved completely following intramesenteric methylprednisolone (MP) injection. In conclusion, intra-arterial steroid injection might be an alternative treatment approach for steroid-refractory GI GVHD.Öğe A new case with a rare nonrandom chromosomal abnormality der(1;15)(q10;q10) associated with trisomy 9 in essential thrombocythemia(Springer, 2013) Acar, Aynur; Bilgin, Aynur Ugur; Zamani, Ayse Gul; Tuncez, Ebru; Yildirim, Mahmut Selman[Abstract Not Availabe]Öğe Successful management of refractory immune thrombocytopenia associated with massive alveolar hemorrhage(Pergamon-Elsevier Science Ltd, 2015) Bilgin, Aynur Ugur; Karaselek, Mehmet Ali; Bilgin, RasimImmune thrombocytopenia (ITP) is an acquired immune-mediated disease characterized by persistant thrombocytopenia. Onset of the disease and the clinical course is highly variable, but the disease typically has a benign course. Patients rarely develop serious life-threatening bleeding. Herein, a case with refractory ITP and massive alveolar hemorrhage who was successfully treated with a fast and sequential approach is presented for the first time. (C) 2015 Elsevier Ltd. All rights reserved.Öğe Successful management of thrombotic thrombocytopenic purpura associated with pregnancy(Pergamon-Elsevier Science Ltd, 2014) Bilgin, Aynur Ugur; Karaselek, Mehmet Ali; Camli, KazimThrombotic thrombocytopenic purpura (TTP) is an uncommon, severe, potentially life-threatening disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, altered mental status, fever, and renal abnormalities. It can be seen at any age or sex but affects women of childbearing age more commonly. Pregnancy is known as one of the most common precipitating events for the onset of TTP and occurs mostly in the late third trimester or during the puerperium. Because of relatively low prevalence of pregnancy-related TTP, here we report the clinical characteristics and successful outcomes of 7 women with pregnancy-related TTP. Median age of patients was 25 (19-32). While 4 out of 7 women were primiparous, others were multiparous. Total plasma exchange (TPE) procedure was started within 24 h after admission to our hospital. All patients got into complete remission without any maternal mortality. Fetal mortality was found to be 28%. Pregnancy-related TTP is still associated with high maternal and fetal mortality rates. However, the prognosis of TTP has improved dramatically with early diagnosis and plasma-based therapies. (C) 2014 Elsevier Ltd. All rights reserved.Öğe Testicular Involvement in Relapsed Hodgkin Lymphoma(Galenos Publ House, 2016) Demircioglu, Sinan; Basturk, Abdulkadir; Bilgin, Aynur Ugur[Abstract Not Availabe]Öğe Translocation t(12;22)(p13;q11) in a patient with AML M1(Springer, 2015) Balasar, Mine; Tasdemir, Pelin; Balasar, Ozgur; Bilgin, Aynur Ugur; Acar, Aynur[Abstract Not Availabe]Öğe The Treatment of Acquired Hemophilia with Combination Therapy of Immunosuppressives and Immunoadsorption(Galenos Yayincilik, 2014) Bilgin, Aynur Ugur; Ozcan, Muhit; Ayyildiz, Erol; Ilhan, Osman[Abstract Not Availabe]
