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    Efficacy of diffusion weighted imaging in sacroiliac joint MRI in children
    (Kare Publ, 2023) Tasar, Sevinc; Ciraci, Saliha; Yilmaz, Pinar Diydem; Oysu, Aslihan Semiz; Bukte, Yasar; Sozeri, Betul
    OBJECTIVE: Because of the immature bone marrow signal in children, assessment of the sacroiliac joint is more difficult than in adults. Aim of this study is to evaluate the efficacy of diffusion-weighted imaging (DWI) in sacroiliac joint magnetic resonance imaging (MRI). METHODS: Sacroiliac joint MRI, including DWI sequences, were evaluated by two pediatric radiologists in 54 patients with sacroiliitis and 85 completely normal controls. In MRI evaluation, subchondral bone marrow edema and contrast enhance-ment in the sacroiliac joints were considered as active sacroiliitis. Apparent diffusion coefficient (ADC) measurements were made in six areas from each sacroiliac joint. A total of 1668 fields were evaluated retrospectively without their diagnosis being known. RESULTS: When the postcontrast T1W series were referenced, the sensitivity, specificity, positive predictive value, and neg-ative predictive value of short time inversion recovery (STIR) images in the diagnosis of sacroiliitis were 88%, 92%, 83% and 94% respectively, compared to contrast-enhanced images. False positive results in STIR images were observed secondary to the flaring signal in the immature bone marrow. ADC measurements obtained from diffusion-weighted images were recorded in all patients and healthy groups. The ADC values were 1.35x10-3 mm2/s (SD: 0.21) in the areas of sacroiliitis, 0.44x10-3 mm2/s (SD: 0.71) in the normal bone marrow and 0.72x10-3 mm2/s (SD: 0.76) in the immature bone marrow areas. CONCLUSION: Although STIR studies are an effective sequence in the diagnosis of sacroiliitis, they cause false positive results in immature bone marrow in children in inexperienced hands. DWI is an objective method that prevents errors in the assessment of sacroiliitis by means of ADC measurements in the immature skeleton. In addition, it is a short and effective MRI series that makes important contributions to the diagnosis without the need for contrast-enhanced examinations in children.
  • Küçük Resim Yok
    Öğe
    Efficacy of diffusion weighted imaging in sacroiliac joint MRI in children
    (Kare Publ, 2023) Tasar, Sevinc; Ciraci, Saliha; Yilmaz, Pinar Diydem; Oysu, Aslihan Semiz; Bukte, Yasar; Sozeri, Betul
    OBJECTIVE: Because of the immature bone marrow signal in children, assessment of the sacroiliac joint is more difficult than in adults. Aim of this study is to evaluate the efficacy of diffusion-weighted imaging (DWI) in sacroiliac joint magnetic resonance imaging (MRI). METHODS: Sacroiliac joint MRI, including DWI sequences, were evaluated by two pediatric radiologists in 54 patients with sacroiliitis and 85 completely normal controls. In MRI evaluation, subchondral bone marrow edema and contrast enhance-ment in the sacroiliac joints were considered as active sacroiliitis. Apparent diffusion coefficient (ADC) measurements were made in six areas from each sacroiliac joint. A total of 1668 fields were evaluated retrospectively without their diagnosis being known. RESULTS: When the postcontrast T1W series were referenced, the sensitivity, specificity, positive predictive value, and neg-ative predictive value of short time inversion recovery (STIR) images in the diagnosis of sacroiliitis were 88%, 92%, 83% and 94% respectively, compared to contrast-enhanced images. False positive results in STIR images were observed secondary to the flaring signal in the immature bone marrow. ADC measurements obtained from diffusion-weighted images were recorded in all patients and healthy groups. The ADC values were 1.35x10-3 mm2/s (SD: 0.21) in the areas of sacroiliitis, 0.44x10-3 mm2/s (SD: 0.71) in the normal bone marrow and 0.72x10-3 mm2/s (SD: 0.76) in the immature bone marrow areas. CONCLUSION: Although STIR studies are an effective sequence in the diagnosis of sacroiliitis, they cause false positive results in immature bone marrow in children in inexperienced hands. DWI is an objective method that prevents errors in the assessment of sacroiliitis by means of ADC measurements in the immature skeleton. In addition, it is a short and effective MRI series that makes important contributions to the diagnosis without the need for contrast-enhanced examinations in children.
  • Küçük Resim Yok
    Öğe
    Morphometric analysis of hippocampus and intracranial formations based on their stages in patients diagnosed with major cognitive disorder
    (Tubitak Scientific & Technological Research Council Turkey, 2022) Yucel, Nurullah; Seker, Muzaffer; Yilmaz, Mehmet Tugrul; Sakci, Zakir; Bukte, Yasar
    Background: Alzheimer???s disease (AD) is a major cognitive disorder classified as a common type of dementia. Magnetic resonance imaging (MRI) is the most practical method for diagnostic purposes in AD. The aim of the study was to determine the volume of the hippocampus and intracranial structures in AD using MRI. Methods: A total of 102 patients with AD were classified based on the mini mental test scores as early, moderate, and advanced stage. The control group included 35 healthy subjects. MRI were compared between the patients and control groups based on the calculations made utilizing volBrain software. Intracranial volumetric parameters were also compared between the three stages of AD. Results: The white matter volumes, total hippocampus, total cerebrum, right cerebrum, left cerebrum, truncus encephalic, total nucleus caudatus and total corpus amygdaloideum were significantly increased in the AD. The white matter volumes, right hippocampus, left hippocampus, total cerebrum, left cerebrum, and right cerebellum were significantly increased in the patients in the early stage compared to the patients in the advanced stage AD. Conclusion: The most efficient volumetric study in AD could be performed by obtaining long-term periodic morphometric data of an early diagnosed and regularly followed-up patient population.