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    Evaluation of Pneumococcal PCR and Urinary Antigen Detection in Children
    (Clin Lab Publ, 2013) Parlakay, Aslinur Ozkaya; Ceyhan, Mehmet; Celik, Melda; Ozsurekci, Yasemin; Oncel, Eda Karadag; Sensoy, Gulnar; Belet, Nursen
    Background: The rapid detection of Streptococcus pneumoniae could assist in the management of pneumococcal infections. The Binax NOW S. pneumoniae test is a rapid immunochromatographic test for this purpose. Methods: Multiplex PCR in parapneumonic pleural effusion fluid (PPEF) and cerebrospinal fluid (CSF) with Binax NOW urinary pneumococcal antigen test (PAT) from 80 children was compared in this study. Results: PAT had a sensitivity of 36.4%, specificity of 97.3%, in CSF. PAT had a sensitivity of 50%, specificity of 81% for parapneumonic pleural effusion fluid. Conclusions: When rapid management of a serious infection is needed the Binax NOW test could be a reliable method for the exclusion of S. pneumoniae infection.