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Öğe Comparison of the Perioperative and Postoperative Effects of Levobupivacaine and of Levobupivacaine plus Adrenaline in Pediatric Tonsillectomy: A Double-Blind Randomized Study(Hindawi Ltd, 2017) Cicekci, Faruk; Sizer, Cigdem; Atici, Sait Selcuk; Arican, Sule; Karaibrahimoglu, Adnan; Kara, InciObjectives. We aimed to assess the effects of levobupivacaine and of levobupivacaine + adrenaline administered during pediatric tonsillectomy on the postoperative period. Methods. A total of 90 patients between the ages of five and twelve were divided randomly into two groups before tonsillectomy: levobupivacaine only (0.5%) 0.4 mg.kg(-1) or levobupivacaine (0.5%) 0.4 mg.kg(-1) + adrenaline (1 :200.000) administered by means of peritonsillar infiltration. Primary outcomes were postoperative pain scores recorded at various intervals until 24 hours postoperatively. Secondary outcomes included postoperative nausea and vomiting (PONV), time to first oral intake, time to the first administration of analgesics and total consumption of analgesics, and the amount of bleeding for all children. Results. In both groups, patients had the same postoperative pain scores and PONV rates, and equal amounts of analgesics were consumed up to 24 hours postoperatively. The two groups also had the same time until first oral intake, recovery time and time to the first analgesic request, and amount of bleeding. Conclusions. Perioperative levobupivacaine infiltration on its own is a valid alternative to the combination of levobupivacaine + adrenaline for perioperative and postoperative effectiveness in pediatric tonsillectomy.Öğe Investigation of granulomatous prostatitis incidence following intravesical BCG therapy(E-Century Publishing Corp, 2014) Balasar, Mehmet; Dogan, Metin; Kandemir, Abdulkadir; Taskapu, Hakan Hakki; Cicekci, Faruk; Toy, Hatice; Gurbuz, RecaiIn the present manuscript, we studied the incidence of granulomatous prostatitis in the prostatectomy specimen of the patients who underwent transurethral resection of the prostate (TURP) after superficial bladder cancer treatment with intravesical Bacillus Calmette-Guerin (BCG) and were diagnosed with benign prostate hyperplasia (BPH). The clinical data and histopathological specimen records of 472 patients who underwent TUR-P due to BPH diagnosis, obtained over a period of 6 years in the urology department of Private Konya Hospital, Konya, Turkey, were studied retrospectively. The cases were divided into two groups as (Group I) who did not undergo any treatment and as (Group II) who underwent BCG treatment. The frequency and the clinical course of the cases with granulomatous prostatitis were studied histopathologically. There were in total 472 patients who underwent TUR-P. Out of the 459 patients who did not undergo BCG treatment (Group I), the histopathological specimen records of 262 (57%) was BPH, of 197 (43%) BPH + chronic prostatitis. Of the second group, 13 cases underwent intravesical BCG treatment before surgical intervention due to superficial bladder CA diagnosis. In this group 4 of the cases were diagnosed as (30%) BPH, 9 as (70%) chronic prostatitis + BPH. 6 out of the 9 chronic prostatitis cases were chronic prostatitis, 2 caseous granulomatous prostatitis, 1 non-caseous granulomatous prostatitis. Granulomatous prostatitis cases should require no specific therapy. Conclusion: In patients with obstruction complaints following intravesical BCG treatment, granulomatous prostatitis should also be considered and treatment plans should be made accordingly.Öğe Oxybutynin addiction amongst prisoners: two case reports(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2016) Balasar, Mehmet; Cicekci, FarukThis study was designed to present two inmates staying Konya E type prison and wanting to increase the prescripttion and/or current dosages of oxybutynin. The study showed that oxybutynin is used to achieve similar feelings to the effects obtained by the use of substance and alcohol among inmates.Öğe Sedation for Colonoscopy: Comparison of Remifentanil and Alfentanil Combined with Propofol/Midazolam(Istanbul Training & Research Hospital, 2019) Ancan, Sule; Cicekci, Faruk; Hacibeyoglu, Gulcin; Sizer, Cigdem; Uzun, Sema Tuncer; Dertli, Ramazan; Keskin, MuharremIntroduction: Different drug combinations are used in patients who underwent colonoscopy for safe sedation and early discharge. Remifentanil and alfentanil are short-acting narcotic analgesic agents. A short-acting anxiolytic agent, midazolam has a potent sedative efficiency when combined with narcotic analgesics. In this study, we aimed to compare the effectiveness of the two opioids that have not been previously compared in the literature, combined with propofol/midazolam in patients who underwent colonoscopy. Methods: One hundred eighty-nine patients aged over 18 years who underwent diagnostic and/or therapeutic colonoscopy were included in the study. 1 mg midazolam + 5 mu g kg-1 alfentanil + 1 mg kg-1 propofol were administered in the alfentanil group (group A), while 1 mg midazolam + 0.1 mu g kg-1 min-1 remifentanil + 1 mg kg-1 propofol were administered in the remifentanil group (group R). Hemodynamic data, Modified Steward scale (MSS), Visual Analog scale (VAS), additional propofol doses, total procedure time, awake time, recovery time, and side effects were recorded during the procedure. After the procedure, all patients were transferred to the recovery room, and the Modified Aldrete scale (MAS) values were recorded. Results: There was a statistically significant difference between the groups in terms of total propofol and additional propofol doses (p<0.05), with additional propofol dose being higher in group A compared to group R (p<0.05). Awake time was similar between the groups. Recovery time was longer in group A compared to group R (p<0.05). No significant difference was observed in the side effects between both groups. Conclusion: Although the low dose of midazolam combined with propofol/remifentanil and propofol/alfentanil provided adequate sedation and analgesia, we believe that remifentanil is an ideal choice for daily procedures like colonoscopy because of its advantages resulting from its pharmacological properties.Öğe Status Epilepticus Development After Organophosphate Intoxication/Midazolam: Case Report(Kare Publ, 2020) Arican, Sule; Cicekci, Faruk; Karacan, MeltemOnset time and severity of symptoms that develop as a result of acute organophosphate intoxication may vary according to the specific compounds and amount ingested and metabolism rate of the substance. Possible signs are compression of the central nervous system, agitation, confusion, delirium, convulsion, and coma. These conditions are relevant to the mortality and morbidity of organophosphate. In this review, we present a patient who developed status epilepticus after acute organophosphate intake. The 32-year-old male patient was completely healthy before taking the organophosphate substance to attempt suicide. During the mechanical ventilator support in the intensive care unit, tonic convulsions started.The patient was not responsive to the diazepam treatment, and the electroencephalography findings showed generalized tonic-clonic convulsions.The seizures were controlled by starting a 0.1 mg/kg midazolam IV. After confirming that the neurological examination and electromyography results of the patient were normal, the patient was discharged in healthy condition on the 12th day.Öğe Status Epilepticus Development After Organophosphate Intoxication/Midazolam: Case Report(Kare Publ, 2020) Arican, Sule; Cicekci, Faruk; Karacan, MeltemOnset time and severity of symptoms that develop as a result of acute organophosphate intoxication may vary according to the specific compounds and amount ingested and metabolism rate of the substance. Possible signs are compression of the central nervous system, agitation, confusion, delirium, convulsion, and coma. These conditions are relevant to the mortality and morbidity of organophosphate. In this review, we present a patient who developed status epilepticus after acute organophosphate intake. The 32-year-old male patient was completely healthy before taking the organophosphate substance to attempt suicide. During the mechanical ventilator support in the intensive care unit, tonic convulsions started.The patient was not responsive to the diazepam treatment, and the electroencephalography findings showed generalized tonic-clonic convulsions.The seizures were controlled by starting a 0.1 mg/kg midazolam IV. After confirming that the neurological examination and electromyography results of the patient were normal, the patient was discharged in healthy condition on the 12th day.