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    Can COVID-19 cause myalgia with a completely different mechanism? A hypothesis
    (Springer London Ltd, 2020) Kucuk, Adem; Cumhur Cure, Medine; Cure, Erkan
    [Abstract Not Availabe]
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    Central involvement of SARS-CoV-2 may aggravate ARDS and hypertension
    (Hindawi Ltd, 2020) Cure, Erkan; Cumhur Cure, Medine; Vatansev, Hulya
    [Abstract Not Availabe]
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    Colchicine may not be effective in COVID-19 infection; it may even be harmful?
    (Springer London Ltd, 2020) Cumhur Cure, Medine; Kucuk, Adem; Cure, Erkan
    [Abstract Not Availabe]
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    Cyclosporine therapy in cytokine storm due to coronavirus disease 2019 (COVID-19)
    (Springer Heidelberg, 2020) Cure, Erkan; Kucuk, Adem; Cumhur Cure, Medine
    [Abstract Not Availabe]
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    Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease
    (Taylor & Francis Inc, 2022) Aydogan Baykara, Rabia; Yilmaz, Pinar Diydem; Goktepe, Mevlut Hakan; Kadiyoran, Cengiz; Ogul, Mustafa; Kucuk, Adem; Cumhur Cure, Medine
    Objectives The incidence of cardiovascular disease is increased in patients with Behcet's disease (BD). Proprotein convertase subtilisin/kexin type 9 (PCSK9) causes the acceleration of atherosclerosis. We aimed to investigate whether there is a relationship between PCSK9 with carotid artery intima-media thickness (cIMT), a marker of subclinical atherosclerosis, and BD disease activity. Methods Fifty-eight patients with BD and 58 age-, gender-, and body mass index (BMI)-matched healthy control subjects were included in the study. The disease activity of the patients was estimated. Individuals' cIMT values were measured, and PCSK9 levels were studied. Results Patients with BD' cIMT (0.51 +/- 0.1 vs 0.41 +/- 0.1 mm, p < .001) and PCSK9 (623.2 +/- 101.7 +/- 10.1 vs 528.3 +/- 242.7 ng/ml, p = .007), values were significantly higher than the control group. In stepwise regression analysis, there was an independent relationship between cIMT with PCSK9 (beta = 0.179, p < .050). There was no independent relationship between disease activities with PCSK9. Based on the ROC curve analysis, the PCSK9 optimal cutoff value for cIMT was 595.1 ng/ml, sensitivity 66.7%, specificity 64.7% (AUC = 0.672; 95% CI: 0.530-0.815, p = .040). Conclusion There is a strong independent association between subclinical atherosclerosis and PCSK9 in patients with BD. There may be no independent association between PCSK9 and disease activity.