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    Evaluation of Changes in The Hematological Parameters, Lipid Profile and Depressive Symptoms Before and After Smoking Cessation Treatment
    (Aves Press Ltd, 2019) Dagistan, Fatma; Kutlu, Ruhusen
    Introduction: Tobacco dependence is a cluster of behavioural, cognitive, and physiological phenomena. We aimed to investigate the changes in the hematological parameters, lipid profile and depressive symptoms before and after smoking cessation. Methods: In this intervention study, 150 casesadmitted to the d in is to quit smoking and stopped smoking for at least three months were investigated. All participants have received motivational interview and appropriate medical treatment (varenicline, bupropion, nicotine replacement therapy). We designed the study to evaluate the effects of cigarette smoking on some biochemical markers and depressive symptoms. Results: Motivational interviews were conducted on all participants, and 68,7% (n = 103) were treated with varenicline, 19,3% (n=29) with bupropion and 12% (n=18) with nicotine replacement therapy (NRT). There was a statistically significant relationship between the treatment method and the smoking cessation duration (p=0.002). Cessation period was longer in the group using varenicline. After quitting smoking, the Beck Depression Scores (BDS) decreased significantly (p<0.001). In cases with smoking duration between 3-6 months, the levels of carbon monoxide (CO) (p<0.001), white blood count (WBC) (p<0.001), hematocrit (p=0.003), hemoglobin (Hb) (p=0.002) and mean corpuscular volume (MCV) (p<0.001) decreased significantly. Conclusions: In our study, positive changes were observed in hematologic, biochemical parameters and depressive symptoms after quitting smoking. So, it is important that the society should be informed about the dangers of smoking. In particular, primary health care physicians should ask each patient whether they smoke or not, and encourage to quit smoking.
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    Frequency and Affecting Factors of Premenstrual Syndrome Among Turkish Female University Students
    (Derman Medical Publ, 2017) Kutlu, Ruhusen; Demirbas, Nur; Dagistan, Fatma
    Aim: Premenstrual syndrome (PMS) refers to physical, cognitive, affective, and behavioral symptoms that occur cyclically during the luteal phase of the menstrual cycle and resolve quickly at or within a few days of the onset of menstruation. Material and Method: This cross-sectional study was conducted among 403 female students attending education and training in Nec-mettin Erbakan University (NEU) Meram Medical Faculty for three months in 2014-2015. The questionnaire included items on students sociodemographic and menstrual pattern characteristics, concerning their age at menarche, menstrual cycle length, and regularity. The menstrual period properties of their mothers were recorded on a pre-prepared form by the researchers. Premenstrual syndrome scale (PMSS) was used to define the severity of symptoms and the presence of PMS. Results: The mean age of the students who participated in the study was 20.67 +/- 1.95 (18-27 years). The mean score of Premenstrual Syndrome Scale was 105.97 +/- 30.45 (44-194). The frequency of PMS was found as 56.6% in this study. When PMS and menstrual features were compared, there was a statistically significant relationship between age (p=0.037), duration of menstruation (p=0.016), and the presence of PMS. Positive direction and very high correlation was found between PMS total score and fatigue, irritability, and depressive thoughts (r=0.826, r=0.788, r=0.833 p<0.000), respectively. Discussion: In this study, the mean score of PMS was high among the university students. Efforts should be made to increase the awareness of premenstrual syndrome among university students and educate them about how to cope with it.