Yazar "Demir, Aysegul" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Comparison of outcomes of transnasal sphenopalatine ganglion and ultrasound-guided proximal greater occipital nerve blockades in chronic migraine
    (Asean Neurological Assoc, 2023) Balta, Selin; Uca, Ali Ulvi; Odabas, Faruk Omer; Demir, Aysegul
    Background & Objective: A need exists for prophylactic treatment options for chronic migraine. Our aim was to evaluate and compare the effect of greater occipital nerve (GON) and transnasal sphenopalatine ganglion (SPG) blockade on headache days, responder rate, attack severity, attack frequency, and medication overuse in patients with chronic migraine. Methods: This was a retrospective study. The GON blockade was performed at the proximal level under ultrasound guidance with 1.5 cc 0.5% bupivacaine, and the SPG blockade was performed transnasally with 0.5 cc 0.5% bupivacaine applied for 30 minutes with swab sticks. Patients who completed bilateral blocks applied in four weekly sessions were included in the analysis. Results: Seventy patients (GON=37, SPG=33) were included in the study. Both groups showed a significant improvement in the number of days with headache, severity of attacks, and frequency of attacks at the first-and third-month follow-up visits compared to the baseline (p<0.001). Responder rates were similar at the first-and third-month follow-up visits (r= 3.707, p=0.054; r=0.071, p=0.790, respectively). At the third-month follow-up, the prevalence of medication overuse decreased from 78% to 13% in the GON group and from 57% to 9% in the SPG group, and these differences were statistically significant (p<0.001 for both groups). No significant difference was noted in efficacy between the treatment groups (p=0.714). No significant adverse effects occurred in either group. Conclusion: Both proximal GON blockade and minimally invasive SPG blockade are effective and safe options for prophylaxis in patients with chronic migraine.
  • Küçük Resim Yok
    Öğe
    The Platelet/Lymphocyte Ratio in Patients with Ischemic Stroke Treated with Intravenous Thrombolysis and Its Relationship with Mortality, Disability, and Prognosis
    (Galenos Publ House, 2021) Eren, Fettah; Demir, Aysegul; Eren, Gullu
    Introduction: The platelet/lymphocyte ratio (PLR) has been studied frequently to determine the prognosis of cardiovascular diseases, chronic inflammatory diseases, and malignancies. Particularly, the PLR is an indicator of systemic inflammation and atherosclerosis. In this study, we aimed to evaluate the value of the PLR and its relationship with mortality, cerebral hemorrhagic transformation, and short-term prognosis in patients with stroke treated with intravenous thrombolysis. Methods: Two hundred fifty stroke patients treated with intravenous thrombolysis were included in the study. Initial symptoms, comorbidities, and localization of cerebral ischemia were recorded. Disability was scored on the National Institutes of Health (NIH) stroke scale. At the 24Th and 72nd hours after treatment, hemorrhagic transformation was evaluated by brain computed tomography. The in-hospital mortality rate was calculated. Patients were divided into groups according to the difference in the NIH stroke scale (between admission and discharge). Serum platelet and lymphocyte levels and PLR values were determined. Results: There were 128 (51.2%) female and 122 (48.8%) male patients included in the study. Their mean age was 71.88 +/- 12.36 years. The lymphocyte count was low and the PLR was high in patients with a high level of initial disability (p<0.01). The lymphocyte count was higher in patients with clinical improvement (p=0.023). The lymphocyte count was lower and the PLR was higher in patients who died (p<0.01). The platelet level was lower in patients with hemorrhagic transformation (p=0.024). The lymphocyte level and PLR were similar in the hemorrhagic transformation groups (p=0.156, p=0.675). Conclusion: In this study, it was determined that mortality is related to the PLR, and hemorrhagic transformation is related to platelet levels in patients with ischemic stroke treated with intravenous thrombolysis.