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Öğe Children with Migraine and Those with Tension-Type Headache for Psychiatric Symptoms and Quality of Life (vol 19, pg 14, 2021)(Georg Thieme Verlag Kg, 2021) Acikel, Sadettin Burak; Bilgic, Ayhan; Derin, Hatice; Eroglu, Arzu; Akca, Omer Faruk; Caksen, Huseyin[Abstract Not Availabe]Öğe Comparison of Children with Migraine and Those with Tension-Type Headache for Psychiatric Symptoms and Quality of Life(Georg Thieme Verlag Kg, 2021) Acikel, Burak Sadettin; Bilgic, Ayhan; Derin, Hatice; Eroglu, Arzu; Akca, Omer Faruk; Caksen, HuseyinThis study compared the severity of depression, anxiety, somatization, anxiety sensitivity, sleep disturbances, and quality of life (QoL) among children with migraine, children with tension-type headache (TTH), and healthy children. A total of 37 children with migraine, 22 with TTH, and a healthy control group (n =35) participated in this study. Children with migraine exhibited higher depression and somatization and lower QoL scores than those in the control group. General sleep disturbances, bedtime resistance, sleep onset delay, sleep duration, sleep anxiety, night wakings, sleep-disordered breathing, and daytime sleepiness scores were also higher in those in the migraine group than in the control group. Regression models indicated that the severity of headache and depression scores significantly affected the QoLs of children with headache disorder as a whole. Migraine is associated with depression, somatization, sleep disturbances, and poor QoL, whereas TTH is associated with only sleep disturbances in childhood. The impact of headache on the QoL occurs mainly through the headache-specific and psychiatric factors.Öğe Intoxication from Ferula sumbul leaves in a mother and her infant(Georg Thieme Verlag Kg, 2013) Derin, Hatice; Yildirim, Gokcen; Caksen, Huseyin[Abstract Not Availabe]Öğe Olfactory Dysfunction in -Thalassemia Major Patients Treated with Iron-Chelating Agents(Sage Publications Inc, 2017) Derin, Serhan; Erdogan, Selvet; Sahan, Murat; Azik, Mehmet Fatih; Derin, Hatice; Topal, Yasar; Topal, HaticeOcular and ophthalmologic adverse effects may occur in patients with -thalassemia major (BTM) treated regularly with blood transfusions and iron-chelating agents. We hypothesized that olfactory dysfunction may be present in this patient population. We aimed to investigate olfactory dysfunction in patients with BTM and to determine etiologic factors. A total of 43 patients with BTM were included in the study. Forty-three subjects without nasal complaints, history of facial trauma, or nasal surgery were included as the controls. All participants had nasal endoscopy. The use of iron-chelating agents by patients with BTM and their duration of use were recorded, as well as hemoglobin and ferritin levels. The Sniffin Sticks test (SST) was used to assess olfactory function, comparing results between the BTM and control groups. The correlations of SST scores with the other study parameters were analyzed. Eight (18.6%) of 43 patients in the BTM group and none of the subjects in the control group had hyposmia (p < 0.001). Older age, low hemoglobin level, and longer use of deferoxamine were found to be correlated with olfactory dysfunction. Olfactory dysfunction can occur in patients with BTM treated with iron-chelating agents. The results suggest that screening for olfactory function should be part of the routine follow-up of patients with BTM.Öğe Olfactory Dysfunction in ? Thalassemia Major Patients Treated With Iron-Chelating Agents(Sage Publications Inc, 2019) Derin, Serhan; Erdogan, Selvet; Sahan, Murat; Azik, Mehmet Fatih; Derin, Hatice; Topal, Yasar; Topal, HaticeOcular and ophthalmological adverse effects may be seen in beta-thalassemia major (BTM) patients treated with regular blood transfusions and iron-chelating agents. We hypothesized that olfactory dysfunction may be present in this population. In this study, we aimed to investigate olfactory dysfunction in patients with BTM and determine the etiological factors. A total of 43 patients with BTM were included in the study. Forty-three patients without any nasal complaints, history of facial trauma, or nasal surgery were included as the controls. All participants had nasal endoscopy. The iron-chelating agents used, their duration of use, as well as hemoglobin and ferritin levels of the BTM patients were recorded. Sniffin' Sticks test (SST) was used to assess olfactory functions, and BTM and control groups were compared for the results. The correlations of SST scores with the other study parameters were analyzed. Eight (18.6%) of 43 patients in the BTM group had hyposmia while none of the patients in the control group had hyposmia (P < .001). Older age, low-hemoglobin level, and longer use of deferoxamine were found to be correlated with olfactory dysfunction. Olfactory dysfunction may be seen in BTM patients treated with iron-chelating agents. The results of this study suggest that screening for olfactory function may be needed in routine follow-up of BTM patients.Öğe A Pediatric Case of Ramsay Hunt Syndrome(Hindawi Ltd, 2014) Derin, Serhan; Derin, Hatice; Sahan, Murat; Caksen, HuseyinRamsay Hunt syndrome (RHS) is characterized by facial paralysis, inner ear dysfunction, periauricular pain, and herpetiform vesicles. The reported incidence in children is 2.7/100,000. The pathogenesis involves the reactivation of latent varicella zoster virus (VZV) in the geniculate ganglion of the facial nerve. The recovery rate is better in children than in adults. This paper discusses a 12-year-old girl with a rare case of peripheral facial paralysis caused by RHS and reviews the literature.Öğe Pediatric Sialadenosis Due to Valproic Acid(Lippincott Williams & Wilkins, 2017) Derin, Hatice; Derin, Serhan; Oltulu, Pembe; Ozbek, Orhan; Caksen, HuseyinSialadenosis is a rare entity characterized by bilateral diffuse, painless swelling of the parotid glands. Its etiology is not clear; however, it may occur due to adverse effects of some drugs. To our knowledge, sialadenosis due to valproic acid has not been reported in the literature up to date in any child. In this article, the authors presented a child who developed sialadenosis due to valproic acid, and improved after stopping use of the drug.Öğe Psychiatric symptoms and health-related quality of life in children with epilepsy and their mothers(Academic Press Inc Elsevier Science, 2018) Bilgic, Ayhan; Isik, Umit; Colak, Rukiye Sivri; Derin, Hatice; Caksen, HuseyinPurpose: This study evaluated the psychiatric symptoms and health-related quality of life (HRQL) of children with epilepsy and psychiatric symptoms of their mothers, and compared them to those of healthy children and their mothers. This study also explored the influence of the child-related and maternal psychiatric variables and seizure-specific factors on the HRQLs of children with epilepsy according to both the children's and parents' perspectives. Method: Ninety-nine children with epilepsy (8 to 17 years old), their mothers, and a control group (n=51) participated in this study. The depression and anxiety symptoms of the children were assessed using the Child Depression Inventory (CDI) and the Screen for Child Anxiety-Related Emotional Disorders (SCARED), respectively. The severities of the attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) symptoms were assessed via the mother-rated Turgay DSM-IV-Based Child and Adolescent Behavioral Disorders Screening and Rating Scale (T-DSM-IV-S). In addition, the mothers completed the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) to assess their depression and anxiety symptoms, respectively. Child-reported and parent-reported Pediatric Quality of Life Inventories were used to evaluate the HRQLs of the children. Results: The patients exhibited higher inattention and ODD scores than the controls did. With the exception of the child-reported physical health scores, all of the child- and parent-reported HRQL scores were significantly lower in the patient group. According to the regression analysis, the child-related psychiatric and seizure-specific factors, but not the maternal psychiatric factors, were associated with the child's HRQL. The explained variances for the overall HRQL and HRQL subscales were similar between the child-reported (0.373 to 0.654) and parent-reported (0.499 to 0.682) questionnaires. The largest contributors to the total variance were the child-related psychiatric factors for both the child-reported and parent-reported HRQLs by far. Conclusion: Epilepsy is associated with a poor psychiatric status and HRQL in childhood. The impact of epilepsy on the HRQL occurs mainly through child-related psychiatric factors. Both the child-reported and parent-reported questionnaires seem to be useful for the evaluation of the HRQL in pediatric epilepsy cases. (C) 2017 Elsevier Inc. All rights reserved.