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Öğe Clinical characteristics and neonatal outcomes of liveborn newborns with hydrops fetalis treated in a tertiary level neonatal intensive care unit(Wiley, 2020) Emiroglu, Nuriye; Yilmaz, Fatma Hilal; Kececi, Ramazan; Yucel, Mehmet; Gultekin, Nazli Dilay; Altunhan, HuseyinBackground This study was performed for examining the neonatal results and aetiological factors of neonates with hydrops fetalis (HF) and determining the factors affecting mortality. Methods The medical records of liveborn neonates with HF who were admitted to a tertiary Neonatal Intensive Care Unit (NICU) in Konya, Turkey, between 2013 and 2019 were reviewed retrospectively. The demographic data, prenatal intervention, clinical findings, and results of the patients were recorded. Results A total of 32.6% of the 46 liveborn HF infants had immune HF (IHF), while 67.4% had nonimmune HF (NIHF); there was prenatal diagnoses in 39 (84.7%) cases. Cordocentesis and blood transfusion (n = 14; 30.4%) were the prenatal diagnosis and treatment interventions with the highest rate. A total of 16 patients (34.7%) received in utero interventional treatment. It was determined that the mean gestational age was not associated with mortality; moreover, birthweight (BW), Apgar score and the need for mechanical ventilation affected mortality. Conclusion The prognosis changes according to different etiologies of HF. However, despite the developments in neonatal care, mortality is still high in HF infants.Öğe Evaluation of blood flow velocity to determine the effect of fortifiers on intestinal hemodynamics(Bayrakol Medical Publisher, 2020) Emiroglu, Nuriye; Altunhan, HuseyinAim: This study aimed to evaluate the effects of human milk fortifier (HMF) formulas on feeding intolerance and intestinal hemodynamics using superior mesenteric artery blood flow velocity (SMA-BFV). Material and Method: The study was conducted on 36 infants born at a gestational age ranging from 26 to 326 weeks. Doppler-ultrasound (USG) was used to measure SMA-BFV. Demographic characteristics, the amount of gastric residue, and the number of stool passages were recorded for each of the patients in this study. Results: The superior mesenteric artery peak systolic velocity (SMA-PSV) increment after HMF was statistically significant (P=0.0011). A statistically significant increase was found in the amount of gastric residue and a significant decrease was found in the number of stool passages after the addition of HMF (p=0.0001 and p=0.034, respectively). Discussion: The use of HMF to achieve appropriate feeding and growth in preterm infants leads to an increase in SMA-BFV, a reduction in the number of stool passages, and an increase in the amount of gastric residue. It does not adversely affect intestinal hemodynamics.Öğe Is the heart of premature babies born as a result of IVF pregnancy different?(Bayrakol Medical Publisher, 2022) Yilmaz, Fatma Hilal; Oflaz, Mehmet Burhan; Altunhan, Hueseyin; Emiroglu, Nuriye; uenal, Emin; Gueltekin, Nazli DilayAim: This prospective study aims to reveal whether preterm births with ART-induced pregnancies are at greater risk of structural and functional cardiac pathologies compared to the control group of preterm births from spontaneous pregnancy.Material and Methods: Between October 2017 and January 2020, 25 premature babies born by means of assisted reproductive techniques (AC) and 25 babies born from spontaneous pregnancy (SC) were included in the study. All babies recruited for the study were born at or below 34 weeks of gestational age. The groups were evaluated in terms of anatomical, m-mode and tissue Doppler systolic and diastolic functions using transthoracic echocardiography (ECHO). Results: The groups were found to be similar in terms of anatomical, m-mode and tissue doppler systolic and diastolic functions by transthoracic ECHO (p=0.156).Discussion: Early diagnosis of possible cardiac diseases is vital for pre-and post-natal management and ultimately for the survival of the infant. Studies should be focused on understanding and eliminating the pathophysiologies increasing the risk of CHD during ever-increasing ART practices.Öğe Is there a relationship between causative microorganisms and hearing loss in neonatal sepsis?(Wiley, 2021) Yilmaz, Fatma Hilal; Emiroglu, Nuriye; Oflaz, Mehmet Burhan; Yucel, Mehmet; Kececi, Ramazan; Arbag, Hamdi; Altunhan, HuseyinBackground The aim of the present study was to determine the possible relationship between cultured microorganisms and hearing loss in infants admitted to the neonatal intensive care unit (NICU) who could not pass a standard hearing test. Method The medical records of infants treated at the NICU were retrospectively evaluated. The patients were first divided into two groups, and group 1 was divided into two subgroups: Group 1 included patients with hearing loss accompanied by proven sepsis caused by either gram-negative (group 1A) or gram-positive (group 1B) bacteria, and group 2 included patients with clinical sepsis. The groups were compared with potential risk factors related to hearing loss. Results Between January 2014 and January 2019, the cases of 3,800 infants admitted to the NICU were reviewed. Of 3,548 living babies, the Auditory Brainstem Response (ABR) test showed that 35 infants (0.98%) were diagnosed with hearing loss. In 12 infants with hearing loss, microbial growth in the blood cultures was detected, whereas in the remaining 23, the blood cultures were negative. Of the cases with microbial growth, five were gram negative and seven were gram positive. In the comparison of groups 1A, 1B, and 2, there were statistically significant differences in terms of risk factors such as low birth weight (p = .048), neonatal hospitalization time (p = .001), free oxygen support (p = .001), intraventricular bleeding (p = .001), loop diuretic use (p = .001), and blood transfusion (p = .048). Conclusion The relationship between hearing loss and microorganisms causing sepsis could not be determined in this research.Öğe Management of Patent Ductus Arteriosus in Preterm Patients Who Were Given Surfactant(Bayrakol Medical Publisher, 2020) Yilmaz, Fatma Hilal; Emiroglu, Nuriye; Oflaz, Mehmet Burhan; Gultekin, Nazli Dilay; Yucel, Mehmet; Kececi, Ramazan; Altunhan, HuseyinAim: Respiratory distress syndrome (RDS) and perinatal asphyxia are known to be risk factors in hemodynamically significant Patent Ductus Arteriosus (hsPDA). In this study, we aimed to reveal scientific data in respiratory distressed preterm infants in the light of the current literature and to discuss the management of PDA in babies born at 33d weeks of gestation and up to 33d weeks which we have treated and followed in our unit. Materials and Methods: The medical records of premature infants treated at Necmettin Erbakan University Neonatal Intensive Care Unit (NICU) between January 2016 and January 2019 were retrospectively evaluated. Results: Between January 2016 and January 2019, 476 patients born prior to 33d gestational weeks were admitted to our unit.. PDA was detected in 149 of these patients because of RDS due to the surfactants. In 112 (75.1%) of these patients, the PDA closed spontaneously within the first week of life. Thirty-seven (24.8%) patients developed hs-PDA. The incidence of premature retinopathy (ROP), bronchopulmonary dysplasia (BPD), and late neonatal sepsis morbidity was significantly elevated during the hospitalization (p=0.05, p=0.01, p=0.06). Invasive mechanical ventilation, non-invasive mechanical ventilation, and free oxygen requirement times were found to be longer (p= 0.0001, p= 0.004, p= 0.014). Complete enteral nutrition and discharge times were longer in the treated group (p= 0.03, p= 0.002). We identified the presence of Small for Gestational Age (SGA) (r = 0.30 p = 0.04) and low birth weight (r = 0.99 p = 0.02) in logistic regression analysis of the factors affecting the PDA as meaningful results. Discussion: The presence of hs-PDA in infants with RDS is directly proportional to the birth week and weight, the presence of SGA reduces the frequency of hs-PDAs, the presence of hs-PDA is associated with ROP, BPD, and late sepsis. The presence of hs-PDA has been found to be correlated with prolonged respiratory support and delayed discharge.Öğe Six Days of a Neonatologist With a Multiple Antiarrhythmics-Resistant Permanent Junctional Reciprocal Tachycardia Case(Bayrakol Medical Publisher, 2020) Yilmaz, Fatma Hilal; Emiroglu, Nuriye; Sap, Fatih[Abstract Not Availabe]
