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    The Assessment of Malnutrition in Child Inpatients
    (Galenos Publ House, 2023) Sahin, Suleyman; Energin, Vesile Meltem
    Introduction: Malnutrition is held responsible for more than 50% of death in childhood. Malnutrition in children, who is so sick that hospitalization is needed, is much more serious since effecting length of stay, morbidity, mortality, quality of life and costs. In this study, we aimed to examine the relationship between malnutrition and nutritional status of hospitalized children during admission together with some demographic factors set by us. Materials and Methods: In this study, 293 children aged 1 month to 18 years old who were hospitalized and monitored in Child Health and Disease Department in Meram Medical Faculty Hospital of Necmettin Erbakan University between November 2014 and January 2015 were included. The survey type information form prepared to collect data about the socio-demographic factors was filled with the consent of the family. Results: Of the 293 cases, 117 (39.9%) were girls, 176 (60.1%) were boys, and the age range was 1 month to 18 years, with a mean age of 5.97 +/- 5.59 years. The average weight of the patients was 22.46 +/- 23.71 kg, the average height was 101.59 +/- 37.82 cm, and the average body mass index was 16.33 +/- 3.42. Malnutrition was not stated in any case. Out of 293, in 154 (52.5%) cases acute malnutrition according to Gomez classification was detected immediately during admission. Out of 293, in 84 (28.6%) patients acute malnutrition according to Waterlow classification was detected immediately during admission. Out of 293, in 131 (44.7%) patients chronic malnutrition was detected immediately during admission. Conclusion: The nutritional risk with child patients during their admissions to our hospital is 52.5% according to Gomez classification, and 28.6% according to Waterlow classification. Hospitalization of children does not have a negative impact on their nutritional status, and unfortunately does not reduce the frequency of high malnutrition which is the main cause of morbidity and of mortality. There is a need to raise awareness of the health professionals about this subject.
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    Evaluation of the Demographical and Clinical Characteristics of the Children with Foreign Body Aspiration: A Single Center Experience
    (2015) Pekcan, Sevgi; Göktürk, Bahar; Güner, Şükrü Nail; Altınok, Tamer; Energin, Vesile Meltem
    Amaç: Yabancı cisim aspirasyonu tespit edilen çocukların, demografik ve klinik özelliklerinin belirlenmesi, ebeveyn eğitim düzeyleri ve gelir seviyesi ile olan ilişkilerinin değerlendirilmesi planlanmıştır. Yöntemler: Çalışmamızda, Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Çocuk Göğüs Hastalıkları bölümüne aspirasyon nedeniyle başvuran ve yabancı cisim çıkartılan 17 hasta çocuğun retrospektif verileri ile aynı yaş ve cinsiyet dağılımına uyan 60 sağlıklı çocuğun demografik özellikleri değerlendirildi. Bulgular: Hastaların yaş ortalaması 14,94,8 ay olup, hastalardan 9'u (%53) erkekti. En sık başvuru şikayeti ani başlayan öksürük (%76,5) ve hışıltı (%64,7) iken, çekirdek (%47) en sık tespit edilen yabancı cisim oldu. Radyolojik incelemede en sık bulgu havalanma farkı (%76,5) iken, cisimler en sık sağ ana bronştan (%47) çıkarıldı. Hasta grubunda bir evde 5 ve üstünde kişi yaşama yüzdesi %76,5 iken, kontrol grubunda %46,6 idi (p0,008). Hasta grubunun gelir düzeyi kontrol grubuna göre belirgin olarak düşüktü (p0,02). Lise ve/veya üniversite eğitimi almamış anne oranı (%94,1), kontrol grubundaki annelere oranla (%63,3) daha yüksekti (p0,03). Sonuç: Bir çocukta ani başlayan öksürük ve hışıltı geliştiği durumlarda yabancı cisim aspirayonu akla gelmelidir. Düşük gelir, kalabalık aile ortamı ve annenin düşük eğitim düzeyi yabancı cisim aspirasyonu açısından önemli risk faktörleri arasında değerlendirilmelidir
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    Evaluation of Vitamin D Level and Iron Deficiency in Six-twenty Four Months Children with Lower Respiratory Tract Infection
    (Galenos Publ House, 2023) Yilmaz, Busra Zeynep; Energin, Vesile Meltem; Pekcan, Sevgi
    Introduction: Lower respiratory tract infections (LRTIs) are defined by the World Health Organization as one of the most important causes of morbidity and mortality in childhood worldwide. This study was conducted to determine the importance of vitamin D level and iron deficiency in the clinical course of the disease in patients aged 6-24 months with LRTI. Materials and Methods: In this study, we included patients who were hospitalized in the pediatric unit due to LRTI at Necmettin Erbakan University Meram Medical Faculty from 6-24 months old. Patients with vitamin D and/or hemogram levels were selected between September 2019 and December 2021. In control group, we choose who applied to our hospital for any reason without LRTI and have vitamin D and or hemogram level in our record. When retrospectively scanned, 82 patients with LRTI s and 84 people in the control group were included. Clinical findings, laboratory values and demographic values of both groups were collected retrospectively. SPSS 22.0 program was used for statistical analysis. A p<0.05 was considered significant. Results: In patient group; 27 (32.9%) were female and 55 (67.1%) were male, in the control group; 46 (54.8%) were female and 38 (45.2%) were male. There was no statistically significant difference between the patients with LRTI and the healthy control group in regard of gender and age. Mean Vitamin D level and Vitamin D level were determined to be significantly lower in the patient group respectively; p=0.01, p=0.037. We evaluated by Vitamin D and hemoglobin level, there was no statistically significant result between the two groups in terms of hospitalization, treatments and clinical severity of LRTI. Vitamin D levels were found to be statistically significantly higher in patients who received vitamin D prophylaxis compared to those who did not (p=0.043). Conclusion: We think that it would be appropriate to evaluate the patients for vitamin D value who followed up with LRTI. Therefore, think that vitamin D supplementation will also prevent recurrence of LRTIs in these patients, should be kept in mind.
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    Serum claudin-5, claudin-11, occludin, vinculin, paxillin, and beta-catenin levels in preschool children with autism spectrum disorder
    (Taylor & Francis Ltd, 2023) Bilgic, Ayhan; Ferahkaya, Hursit; Karagoez, Huelya; Kilinc, Ibrahim; Energin, Vesile Meltem
    Aim Increased intestinal and blood-brain barriers (BBB) permeability has been suggested to have a role in autism spectrum disorder (ASD). Claudin-5, claudin-11, occludin, beta-catenin, vinculin, and paxillin are crucial components of these barriers. This study assessed concentrations of these molecules in preschool children with ASD.Methods A total of 80 children with ASD and 40 controls aged 18-60 months were enrolled in this study. Serum levels of biochemical variables were determined using commercial enzyme-linked immunosorbent assay kits.Results Serum claudin-11, occludin, and beta-catenin levels were significantly higher in the ASD group than in the control group. However, no significant difference for serum claudin-5, vinculin, and paxillin levels was detected between the groups.Conclusion These findings suggest that claudin-11, occludin, and beta-catenin may be involved in the pathogenesis of ASD. These proteins may affect the brain by causing dysregulation in intestinal or blood-brain barrier permeability or with other unknown mechanisms.