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    The association between neurocognitive functioning and clinical features of borderline personality disorder
    (Assoc Brasileira Psiquiatria, 2020) Kaplan, Bahar; Gulec, Medine Yazici; Gica, Sakir; Gulec, Huseyin
    Objective: To investigate the relationship between neurocognitive profiles and clinical manifestations of borderline personality disorder (BPD). Methods: Forty-five patients diagnosed with BPD and 35 healthy volunteers were included in the study. The BPD group was evaluated with the Borderline Personality Inventory for dissociative, impulsivity and suicidal dimensions. The Verbal Memory Processes Test and the Cambridge Neurophysiological Assessment Battery were administered to both the BPD and healthy control groups. Results: BPD patients differed from controls in sustained attention, facial emotion recognition, and deteriorated verbal memory function. A model consisting of the Dissociative Experiences Scale Taxon (DES-T), motor impulsivity and Scale for Suicidal Behavior scores explained 52% of the variance in Borderline Personality Inventory scores. It was detected that motor impulsivity, decision-making and recognizing sadness may significantly predict DES-T scores, and response inhibition and facial emotion recognition scores may significantly predict impulsivity. Conclusion: Our findings demonstrate that the disassociation, impulsivity, and suicidality dimensions are sufficient to represent the clinical manifestations of BPD, that they are related to neurocognitive differences, and that they interact with clinical features.
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    The association between neurocognitive functioning and clinical features of borderline personality disorder
    (Assoc Brasileira Psiquiatria, 2020) Kaplan, Bahar; Gulec, Medine Yazici; Gica, Sakir; Gulec, Huseyin
    Objective: To investigate the relationship between neurocognitive profiles and clinical manifestations of borderline personality disorder (BPD). Methods: Forty-five patients diagnosed with BPD and 35 healthy volunteers were included in the study. The BPD group was evaluated with the Borderline Personality Inventory for dissociative, impulsivity and suicidal dimensions. The Verbal Memory Processes Test and the Cambridge Neurophysiological Assessment Battery were administered to both the BPD and healthy control groups. Results: BPD patients differed from controls in sustained attention, facial emotion recognition, and deteriorated verbal memory function. A model consisting of the Dissociative Experiences Scale Taxon (DES-T), motor impulsivity and Scale for Suicidal Behavior scores explained 52% of the variance in Borderline Personality Inventory scores. It was detected that motor impulsivity, decision-making and recognizing sadness may significantly predict DES-T scores, and response inhibition and facial emotion recognition scores may significantly predict impulsivity. Conclusion: Our findings demonstrate that the disassociation, impulsivity, and suicidality dimensions are sufficient to represent the clinical manifestations of BPD, that they are related to neurocognitive differences, and that they interact with clinical features.
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    Investigation of auditory P50 sensory gating with sexual visual stimuli in patients with vaginismus
    (Elsevier France-Editions Scientifiques Medicales Elsevier, 2021) Yukselay, Ozge; Gica, Sakir; Yalcin, Murat; Gulec, Medine Yazici; Gulec, Huseyin
    Objectives. - The aim of the study was to investigate sensory information processing induced by visual sexual stimuli and to assess its relationship with sexual behaviors and symptoms in patients with vaginismus. Methods. - Twenty-one patients with vaginismus and 20 controls were included in the study. The sociodemographic information and sexual life history of the patients with vaginismus and controls were examined and electrophysiological measurements related to auditory P50 sensory gating were obtained using a double click paradigm during by sexual/horror visual stimulation, which was thought to be related to the pathophysiology of the disease. Results. - P50 suppression ratios during visual sexual stimuli were lower in vaginismus group compared to the control group. There was no difference in P50 suppression ratios during visual horror stimuli when the two groups were compared. The P50 suppression of the vaginismus group with visual sexual stimuli was found to be lower than P50 suppression with visual horror stimuli. A positive moderate correlation was found between the duration of foreplay and P50 suppression ratio during visual sexual stimuli in vaginismus group. Conclusion. - Our study revealed that patients with vaginismus had sensory gating impairment during visual sexual stimuli. Increase in the duration of foreplay in vaginismus patients may improve sensory gating impairment by affecting sensory gating functions. (C) 2021 Elsevier Masson SAS. All rights reserved.
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    Investigation of the effects of childhood sexual abuse on disease severity and cognitive functions in borderline personality disorder
    (Kare Publ, 2021) Gica, Sakir; Kaplan, Bahar; Atar, Ayse Terzi; Gulec, Medine Yazici; Gulec, Huseyin
    Objective: The aim of this study is to investigate the effects of childhood sexual abuse (CSA) on decision-making, facial emotion recognition, and clinical presentation of borderline personality disorder (BPD). In addition, it was examined whether certain cognitive impairments could be worsened by the presence of CSA. Method: Eighteen sexually abused BPD patients, 18 patients with BPD without CSA, and 35 healthy controls were included in the study. The Borderline Personality Inventory (BPI) and the Childhood Trauma Questionnaire (CTQ) were administered to BPD patients. The Cambridge Neuropsychological Test Automated Battery (CANTAB), which is used to examine decision-making and emotional recognition, was administered to the patients and healthy controls. Results: In the emotion recognition test, the mean percentages of correct fear recognition were 33.5 +/- 14.6 for patients with CSA, 25.89 +/- 9.8 for patients without CSA, 26.8 +/- 7.4 for healthy controls. The mean percentage of correct fear recognition was higher in patients with CSA than in the other groups. There was no difference in the correct recognition of other emotions between the groups. The probability of risking a 10% chance of winning in patients with/without CSA and healthy controls averaged were 0.71 +/- 0.26, 0.33 +/- 0.28, and 0.25 +/- 0.20 respectively. The average risk-taking propability in patients with CSA was significantly higher than in other groups. A significant correlation was identified between BPI and CTQ scores. Conclusion: The present study supports the fact that CSA has significant effects on the clinical presentation and neurocognitive profiles of BPD.
  • Küçük Resim Yok
    Öğe
    Investigation of the effects of childhood sexual abuse on disease severity and cognitive functions in borderline personality disorder
    (Kare Publ, 2021) Gica, Sakir; Kaplan, Bahar; Atar, Ayse Terzi; Gulec, Medine Yazici; Gulec, Huseyin
    Objective: The aim of this study is to investigate the effects of childhood sexual abuse (CSA) on decision-making, facial emotion recognition, and clinical presentation of borderline personality disorder (BPD). In addition, it was examined whether certain cognitive impairments could be worsened by the presence of CSA. Method: Eighteen sexually abused BPD patients, 18 patients with BPD without CSA, and 35 healthy controls were included in the study. The Borderline Personality Inventory (BPI) and the Childhood Trauma Questionnaire (CTQ) were administered to BPD patients. The Cambridge Neuropsychological Test Automated Battery (CANTAB), which is used to examine decision-making and emotional recognition, was administered to the patients and healthy controls. Results: In the emotion recognition test, the mean percentages of correct fear recognition were 33.5 +/- 14.6 for patients with CSA, 25.89 +/- 9.8 for patients without CSA, 26.8 +/- 7.4 for healthy controls. The mean percentage of correct fear recognition was higher in patients with CSA than in the other groups. There was no difference in the correct recognition of other emotions between the groups. The probability of risking a 10% chance of winning in patients with/without CSA and healthy controls averaged were 0.71 +/- 0.26, 0.33 +/- 0.28, and 0.25 +/- 0.20 respectively. The average risk-taking propability in patients with CSA was significantly higher than in other groups. A significant correlation was identified between BPI and CTQ scores. Conclusion: The present study supports the fact that CSA has significant effects on the clinical presentation and neurocognitive profiles of BPD.