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    Attention deficit-hyperactivity disorder symptoms in women with polycystic ovary syndrome
    (Sage Publications Inc, 2015) Herguner, Sabri; Harmanci, Hatice; Toy, Harun
    Objectives Several studies suggest that androgens are involved in the etiology of attention deficit-hyperactivity disorder (ADHD). In this study, we investigated the ADHD symptoms in women with polycystic ovary syndrome (PCOS), a complex endocrine, hormonal, and metabolic condition associated with hyperandrogenism. Methods Forty women between the ages of 18 and 35 years with PCOS were recruited for the study group. For comparison, 40 healthy women who had regular menses were included. Current and childhood ADHD symptoms were assessed by using the Adult ADHD Self-Report Scale and Wender-Utah Rating Scale, respectively. Results Women with PCOS had higher total Adult ADHD Self-Report Scale and total Wender-Utah Rating Scale scores than controls. According to the Wender-Utah Rating Scale, the frequency of childhood ADHD was significantly higher in PCOS group than the control. Adult ADHD Self-Report Scale: Hyperactivity-Impulsivity and Wender-Utah Rating Scale: Behavioral Problems/Impulsivity scores were significantly higher in women with PCOS. However, there were no significant differences between groups in both current and childhood inattention scores. We found no correlations between ADHD symptoms and serum hormone levels including testosterone in women with PCOS. Conclusions These results suggest that women with PCOS have higher ADHD symptoms. Further studies are needed to investigate the association between PCOS and ADHD.
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    Autistic traits in women with polycystic ovary syndrome
    (Elsevier Sci Ltd, 2012) Herguner, Sabri; Harmanci, Hatice; Herguner, Arzu; Toy, Harun
    Several studies suggested that prenatal androgen exposure might contribute to development of polycystic ovary syndrome (PCOS). The androgen theory of autism proposes that autism spectrum conditions (ASC) are in part due to elevated fetal testosterone levels. Furthermore, higher rates of androgen-related conditions including PCOS are reported in women with ASC. In this study, we aimed to measure the autistic traits in women with PCOS. Forty females who had a diagnosis of PCOS were recruited for the study group. For comparison, 40 healthy age - and Body Mass Index (BMI) - matched women who had regular menses were included. All participants completed the Autism-Spectrum Quotient (AQ). There were no significant differences in age, education, and BMI between groups. Total AQ and communication scores were statistically higher in females with PCOS. Although social skills, imagination, attention to detail and attention switching scores were higher in women with PCOS, these did not reach significance. This study showed that autistic traits were higher in women with PCOS than healthy controls which supports that prenatal exposure to high levels of androgen may be involved in development of ASC. (C) 2012 Elsevier Ltd. All rights reserved.
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    The Effect of Video Assisted Information on Anxiety and Pain Associated with Intrauterine Device Insertion
    (Karger, 2020) Eric, Jule; Purut, Yunus Emre; Harmanci, Hatice
    Introduction: Fear of procedural pain or stress may be a barrier to women accessing intrauterine device (IUD) for contraception. The aim of this study is to evaluate the effect of video-assisted information on the anxiety and pain levels of patients undergoing IUD placement procedure. Methods: A total of 100 patients who underwent IUD insertion were prospectively enrolled in this observational case-control study. Study group included 50 patients who received both verbal and video-based information, while control group included 50 patients who received only verbal information regarding IUD insertion. The anxiety of the participants was measured by Spielberger's State-Trait Anxiety Inventory (STAI) scale, both before and after the IUD insertion. State Anxiety Scale (STAI-S) was used to evaluate the current anxiety levels, and Trait Anxiety Scale (STAI-T) was used to evaluate the general and stable aspects of anxiety. Pain was measured using visual analog scale (VAS) immediately after the IUD insertion procedure. Results: There was no statistically significant difference between the pre-intervention STAI-S and STAI-T scores between the study and control groups (p = 0.098 for STAI-S, p = 0.641 for STAI-T). Similarly, there was no statistically significant difference between the post-intervention STAI-S score between the groups (p = 0.381). However, pain scores measured by VAS were significantly lower in the study group when compared with the control group (p < 0.001). Conclusion: Video-assisted information about IUD insertion did not have a reducing effect on anxiety, but was associated with a statistically significant decrease in pain.
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    Pain catastrophizing in patients with primary dysmenorrhea: Its relationship with temperament traits and impulsivity
    (Bayrakol Medical Publisher, 2021) Harmanci, Hatice; Horasanli, Jule Eric
    Aim: The objective of this study was to evaluate the relationship between clinical pain and pain catastrophizing (PC) cognition in primary dysmenorrhea (PD). Moreover, this study evaluates the effects of temperament characteristics and impulsivity levels on PC. Material and Methods: In this study, 258 patients who were diagnosed with PD and met the inclusion criteria were included. According to the Andersch and Milsom Scale, the patients were divided into two groups. Group 1 consisted of those whose functionality was impaired at moderate and severe levels due to pain, whereas Group 2 consisted of those whose functionality was not impaired at all and those who are mildly affected. Socio-demographic data form and the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire, Pain Catastrophizing Scale, and the Short Form of Barratt Impulsiveness Scale were applied to all patients. Results: The functionality of patients with PD was significantly impaired by 53.1%, and the main symptom determining functionality was pain. The total and subscale PCS score averages in Group 1 were significantly higher than those in Group 2. Cyclothymic temperament and impulsivity explained 20% of the variance on PC. Discussion: Psychological factors have an important role in managing PD. For this reason, both gynecological and psychiatric evaluations of patients with PD during treatment and the multidisciplinary treatment approach to be applied when necessary will improve the patients' quality of life and help them easily cope with symptoms.