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Öğe Comparison of maternal and perinatal outcomes of pregnancies with frozen and fresh embryo transfers at term pregnancy Frozen and fresh embryo transfer results(Bayrakol Medical Publisher, 2022) Horasanli, Jule Eric; Energin, Hasan; Ferlibas, EnesAim : In our study, we aimed to compare maternal and perinatal outcomes of frozen and fresh embryo transfers, induced by single or double embryo transfer with in vitro fertilization (IVF) at term pregnancy. Material and Methods: After obtaining ethics, our study was performed retrospectively assessing pregnancies in women between the ages of 18 and 40 induced with single or double embryo transfer with IVF between the years 2010 and 2020. Maternal outcomes such as oligohydramnios, polyhydramnios, preeclampsia, placenta previa, placenta accreta syndrome (PAS). and hysterectomy were examined in all groups. Perinatal outcomes including birth weight, time of delivery, small for gestational age (SGA), large for gestational age (LGA), appropriate for gestational age (AGA), preterm labor, Apgar score of infant at five minutes, and intensive care requirement were also investigated. Results: No difference was observed in terms of oocyte number collected, neonatal intensive care requirement. Apgar scores. postpartum hysterectomy, and blood transfusions. There was no difference between the groups in birth weight, preterm labor, and delivery time. There was no significant difference between the groups in SGA, LGA, and AGA. Polyhydramnios and oligohydramnios were significantly higher in the fresh transfer group (p - 0.006 and p - 0.006, respectively). Among perinatal parameters, the frequency of placenta previa was significantly higher in the frozen transfer group (p - 0.001). The frequency of placenta accreta and preeclampsia was not significantly different. Discussion: Placenta previa was higher in the frozen transfer group, suggesting frozen embryo transfer increases the risk of placenta previa. Oligohydramnios and polyhydramnios were higher in the fresh transfer group.Öğe Effect of anterior repair on sexual function in heterosexual couples(Springer London Ltd, 2023) Energin, Hasan; Horasanli, Jule EricIntroduction and hypothesis Little is known about the impact of native tissue repair techniques on heterosexual intercourse. This study was aimed at investigating the effect of anterior colporrhaphy on women's and their partners' sexual function.Methods Sexually active women with a male partner who were diagnosed with anterior wall prolapse without any incontinence were prospectively recruited from a single academic center. Demographic data were collected and a Pelvic Organ Prolapse Quantification examination was performed. Before and 3 months post-operatively, women completed two validated questionnaires to assess sexual function, the International Consultation on Incontinence Questionnaire Vaginal Symptoms short form (ICIQ-VS SF) 55, and the Female Sexual Function Index (FSFI), and their male partners completed the International Index of Erectile function-5. Pre-and post-operative results were compared using a paired t test.Results This study was conducted in the gynecology department of a university hospital between May 2022 and June 2023, where 50 heterosexual couples were enrolled and underwent isolated anterior repair. The mean age of women and their partners were 44.3 +/- 5.12 and 48.1 +/- 5.81 respectively. Overall, female sexual function improved significantly from pre-to 3 months postoperatively with a decrease in ICIQ-VS SF scores from 13.3 +/- 3.27 to 1.7 +/- 1.1 (p < 0.05) and an increase in FSFI scores from 21.74 +/- 9.37 to 29.28 +/- 9.97 (p < 0.05). The only domain that did not improve was sexual pain. For their male partners, there was a similar significant improvement in sexual function with an increase in scores from 48.71 +/- 8.71 to 60.68 +/- 8.63 (p < 0.05).Conclusions Isolated anterior repair was associated with improved short-term sexual function amongst heterosexual couples.Öğe Effects of Music Intervention During Cesarean Section on the Level of the Mother's Anxiety: A Randomized Controlled Study(Erciyes Univ Sch Medicine, 2022) Horasanli, Jule Eric; Demirbas, NurObjective: Anxiety felt before and during childbirth can have negative effects on maternal and infant health. Music interventions during labor have been shown to mitigate the effects of anxiety in a variety of populations. It is a low-cost and easily accessible technique that also has a high level of acceptability. The aim of this study was to examine the effect of listening to music on the vital signs of women during a cesarean section (C-section) and their level of anxiety. Materials and Methods: This was a single-center, controlled, randomized study. The pregnant women in the intervention group listened to Sufi music via earphones during the operation. The control group received standard treatment without music. The C-section was performed under regional anesthesia in all cases. The State-Trait Anxiety Inventory (STAI) was administered to the patients before and after the procedure. Results: There was no significant difference in the vital sign parameters of the music group and the control group (p>0.05). The preoperative STAI anxiety score was similar in the music (45.58 +/- 4.60) and control (43.82 +/- 4.33) groups (p=0.183). However, after the operation, the anxiety score of the music group (35.88 +/- 5.39) was statistically significantly lower than that of the anxiety score of the control group (42.14 +/- 3.75) (p<0.001). Conclusion: The women who listened to Sufi music during a C-section reported less anxiety. Slow, rhythmic music can distract the patient, help them relax, and reduce their anxiety.Öğe Effects of Music Intervention During Cesarean Section on the Level of the Mother's Anxiety: A Randomized Controlled Study(Erciyes Univ Sch Medicine, 2022) Horasanli, Jule Eric; Demirbas, NurObjective: Anxiety felt before and during childbirth can have negative effects on maternal and infant health. Music interventions during labor have been shown to mitigate the effects of anxiety in a variety of populations. It is a low-cost and easily accessible technique that also has a high level of acceptability. The aim of this study was to examine the effect of listening to music on the vital signs of women during a cesarean section (C-section) and their level of anxiety. Materials and Methods: This was a single-center, controlled, randomized study. The pregnant women in the intervention group listened to Sufi music via earphones during the operation. The control group received standard treatment without music. The C-section was performed under regional anesthesia in all cases. The State-Trait Anxiety Inventory (STAI) was administered to the patients before and after the procedure. Results: There was no significant difference in the vital sign parameters of the music group and the control group (p>0.05). The preoperative STAI anxiety score was similar in the music (45.58 +/- 4.60) and control (43.82 +/- 4.33) groups (p=0.183). However, after the operation, the anxiety score of the music group (35.88 +/- 5.39) was statistically significantly lower than that of the anxiety score of the control group (42.14 +/- 3.75) (p<0.001). Conclusion: The women who listened to Sufi music during a C-section reported less anxiety. Slow, rhythmic music can distract the patient, help them relax, and reduce their anxiety.Öğe Evaluation of knowledge, attitude and awareness of medical faculty students about human papilloma virus Medical faculty students HPV; Knowledge level; Awareness; Vaccine(Bayrakol Medical Publisher, 2021) Horasanli, Jule Eric; Demirbas, NurAim: In this study, we aimed to evaluate the knowledge levels and awareness of medical students about the diagnosis, transmission routes and prevention methods of Human Papiiloma Virus (HPV), which is very common worldwide. Materials and Methods: This cross-sectional study was carried out on 4th grade medical faculty students in the 2019-2020 academic year. A brief sociodemographic information form, an information form on general knowledge, diagnosis, contamination routes, and methods of HPV prevention, and a questionnaire on HPV awareness levels were applied to the students. Results: The average age of the students was 22.31 +/- 1.3 (19-30) years; 44.5% (n 89) of the students were female and 55.5% (n = 111) were male. Among the students, 84% had information about the diseases caused by the virus, transmission routes, prevention and diagnostic methods. The correct response rate of students to knowledge questions was 84.4% for women and 82.7% for men (p = 0.042). It was found that students' levels of knowledge about HPV protection methods and especially vaccines were lower than their knowledge about diagnosis and transmission. Discussion: In this study, it was found that the general knowledge level of medical school students about HPV was high, but their knowledge about prevention and vaccination was low. Medical school students should be encouraged to increase their knowledge and get vaccinated, and importance should be given to HPV vaccination training.Öğe Investigation of peripheral natural killer cell activity in recurrent miscarriages of unknown cause(Bayrakol Medical Publisher, 2023) Alyazova, Elnare; Babayeva, Gulchin; Colakoglu, Mehmet Cengiz; Horasanli, Jule EricAim: Recent studies on alloimmune factors have shown that Natural Killer (NK) cells may have a role in the implantation and maintenance of pregnancy. It is unclear precisely what kind of relationship exists between uterine and peripheral blood NK cells. Our study aims to investigate the relationship between pNK cells and recurrent pregnancy loss. Material and Methods: Among the patients who applied to the outpatient clinic at University Hospital, retrospectively, women with two or more pregnancy losses constituted the RM group, and women with two or more live births and no miscarriage formed the control group. Two or more miscarriages before 20 weeks of gestation were accepted as the criterion to consider a case of recurrent pregnancy loss. Results: To investigate the etiology of miscarriage in RM patients, parameters associated with the cytotoxicity of pNK cells in women with RM and control fertile women were evaluated. Although the median pNK activity level was relatively higher in the recurrent low group compared to the control group, there was no significant difference between the groups in our study (p=0.448). Discussion: The present study found no significant difference in the percentages of CD56+dim and CD56+bright pNK cells between the patient group with unexplained RM and the healthy fertile control group. There was also no significant difference in CD8 and CD158a expressions in pNK cells between the patient group with unexplained RM and the healthy fertile control group.Öğe The level of knowledge about menopause and attitudes towards menopause in women in the climacteric period Menopause attitudes and knowledge levels of women(Bayrakol Medical Publisher, 2021) Horasanli, Jule Eric; Demirbas, NurAim: This study aimed to determine the level of awareness and knowledge about menopause in women aged 40-65 in the climacteric period, and examine the symptoms of menopause and the relationship with their attitudes towards menopause. Material and Methods: The study included 224 women who applied to Obstetrics and Family Medicine outpatient clinics. The Sociodemographic Information Form, Menopause Information and Awareness Form, Menopause Attitude Assessment Scale (ATMS), and the Menopause Rating Scale (MRS) were applied to the participants. Results: Among the participants, 71.0% had gone through menopause, whereas 21.0% had not, and 8.0% did not know whether they had gone through menopause or not. The mean age of the women who had gone through menopause was 47.79 +/- 4.5 years. While the mean ATMS score was 43.97 +/- 10.93, 37.9% of the women had a negative attitude (40 points and below). The mean MRS somatic complaint score was 6.43 +/- 3.74, the mean psychological complaint score was 6.21 t4.09, and the mean urogenital complaint score was 3.88t2.65. There was a moderately significant negative correlation between their ATMS scores and their menopause-related psychological complaints (p.-0.317, p<0.001). As their positive attitude towards menopause increased, theft psychological complaints decreased. As their awareness of menopause increased, their psychological complaints decreased. Discussion: Increased awareness of menopause provided a decrease in the psychological complaints of menopause. In the study, it was seen that the attitudes of women toward menopause were an effective variable in the emergence of menopause complaints. Improving the attitudes of the women towards menopause is important for reducing menopausal symptoms.Öğe Pain catastrophizing in patients with primary dysmenorrhea: Its relationship with temperament traits and impulsivity(Bayrakol Medical Publisher, 2021) Harmanci, Hatice; Horasanli, Jule EricAim: The objective of this study was to evaluate the relationship between clinical pain and pain catastrophizing (PC) cognition in primary dysmenorrhea (PD). Moreover, this study evaluates the effects of temperament characteristics and impulsivity levels on PC. Material and Methods: In this study, 258 patients who were diagnosed with PD and met the inclusion criteria were included. According to the Andersch and Milsom Scale, the patients were divided into two groups. Group 1 consisted of those whose functionality was impaired at moderate and severe levels due to pain, whereas Group 2 consisted of those whose functionality was not impaired at all and those who are mildly affected. Socio-demographic data form and the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire, Pain Catastrophizing Scale, and the Short Form of Barratt Impulsiveness Scale were applied to all patients. Results: The functionality of patients with PD was significantly impaired by 53.1%, and the main symptom determining functionality was pain. The total and subscale PCS score averages in Group 1 were significantly higher than those in Group 2. Cyclothymic temperament and impulsivity explained 20% of the variance on PC. Discussion: Psychological factors have an important role in managing PD. For this reason, both gynecological and psychiatric evaluations of patients with PD during treatment and the multidisciplinary treatment approach to be applied when necessary will improve the patients' quality of life and help them easily cope with symptoms.
