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    Association between Red Blood Cell Distribution Width and Acute Pancreatitis
    (Int Scientific Information, Inc, 2014) Karabulut, Keziban Ucar; Narci, Huseyin; Ucar, Yildiz; Uyar, Mehmet
    Background: We aimed to determine whether there are any alterations in red blood cell width in patients diagnosed with acute pancreatitis. Material/Methods: This was a retrospective study of records of patients treated in emergency units and diagnosed with acute pancreatitis between January 2011 and April 2013. Records were investigated regarding patient age, sex, and causes of acute pancreatitis. Red blood cell width and amylase values obtained from the patients during diagnosis and after a full recovery from acute pancreatitis were added to the records. Results: Recorded red blood cell width and amylase values of 104 patients diagnosed with acute pancreatitis were statistically compared according to the time of sample collection. Samples were collected in the post-diagnostic period and after full recovery. Values of red blood cell width and amylase were found to be significantly higher in samples collected during hospital admission in comparison to those obtained from patients after fully recovering from acute pancreatitis (p<0.05). Conclusions: An increase in red blood cell width value is a marker of acute pancreatitis; therefore, we suggest that red blood cell width can be used as a tool for the early diagnosis and assessment of disease progression.
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    The change of neutrophils/lymphocytes ratio in migraine attacks: A case-controlled study
    (Elsevier Sci Ltd, 2016) Karabulut, Keziban Ucar; Egercioglu, Tomris Ugur; Uyar, Mehmet; Ucar, Yildiz
    Objective: As commonly seen symptoms, headaches are among the most frequently encountered health challenges in emergency rooms by healthcare professionals. Among one of the most commonly seen and primary headaches is migraine. Migraines are mostly accompanied by functional deficits. Aims: To observe the changes of neutrophil/lymphocyte ratio occurring during migraine attacks. Method: This is a retrospective study where hospital records of patients previously diagnosed with migraine and admitted to the emergency with the complaints of attacks between May 2014 and January 2015 were investigated. All patients in the study were evaluated as to age, gender and complete blood count. Additionally, a healthy control group was formed with individuals with no disorders. By also evaluating the same features in the controls, the values found in the patients and controls alike were compared. Results: The values of white blood cell, lymphocyte, neutrophil, hemoglobin, thrombocyte and neutrophil/lymphocyte ratio determined in the patient group (n = 92) were statistically compared with those of the controls (n = 67). Neutrophil/lymphocyte ratio during the attacks was found higher in the patients, compared to the controls. Conclusion: Neutrophil/lymphocyte ratio is a sign of inflammation, and we consider that this ratio will also increase during migraine attacks, as with other inflammatory and acute processes. (C) 2016 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
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    Diamine oxidase in diagnosis of acute mesenteric ischemia
    (W B Saunders Co-Elsevier Inc, 2013) Karabulut, Keziban Ucar; Narci, Huseyin; Gul, Mehmet; Dundar, Zerrin Defne; Cander, Basar; Girisgin, A. Sadik; Erdem, Sami
    Objective: Acute mesenteric ischemia (AMI) is an important clinical condition with a high mortality rate in abdominal emergencies due to delay in diagnosis in spite of the new strategies in the management. We have studied the role of diamine oxidase (DAO) in the early diagnosis of AMI. Methods: In the study, 21 New Zeland rabbits were used. Subjects were named as the groups of controls, sham, and ischemia. No intervention was performed in the subjects in the control group. In the subjects from sham and ischemia groups, laparotomy was performed with middle line incision. However, superior mesenteric artery was found and tied in those from ischemia group after the performance of laparotomy. From the animals in 3 groups, blood was drawn at the hours of 0, 1, 3, and 6, and DAO and amylase were studied in these samples. Results: The increase in serum amylase levels was found to be statistically significant in the ischemia group compared with the control and the sham groups (P < .05). The decrease in serum DAO levels was found to be statistically significant in the ischemia group compared with the control and the sham groups (P < .05). Diamine oxidase levels were found to decrease, beginning from the 1 hour after ischemia had been developed, and this rise was found to continue for 6 hours (P < .05). Conclusion: Serum DAO levels were decreased in ischemia. Further clinical and experimental investigations would be valuable to confirm the probable role of DAO in AMI. (c) 2013 Elsevier Inc. All rights reserved.
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    Which site is least painful during intravenous cannulation?
    (Derman Medical Publ, 2018) Karabulut, Keziban Ucar; Girisgin, Abdullah Sadik
    Aim: The aim was to determine the least painful cannulation site in patients via the Visual Analogue Scale. Material and Method: Of 104 patients (53 women) admitted to the Emergency Department of Meram Medical School of Necmettin Erbakan University, 45 were cannulated through antecubital site, 33 by wrists and 26 via dorsal. No difference was detected between groups as to age and gender. All cases were cannulated by the same nurse using pink cannulas. The patients were asked to mark the severity of pain during procedure on the Visual Analogue Scale where scores range from 0 to 10. Results: When a significant difference was found between the groups via the Kruskal-Wallis test as to the Visual Analogue Scale scores, the Mann-Whitney-U test with Boferroni correction was performed. Therefore, while the pain on antecubital site was found to be significantly lower during cannulation compared to that found on wrist and dorsal, no difference was found between the pain scores detected on wrist and dorsal. Discussion: The antecubital site, a commonly used area for cannulation, was determined to be the least painful area when compared to other sites. It provides easy access to the vein, which may why it is commonly used, and may also be one of the reasons. It is the least painful area during cannulation. In the present study performed in 104 patients, the antecubital area was significantly the least painful cannulation site compared to wrist and dorsal. In patients required to be cannulated, the antecubital site is considered preferable due to painlessness unless specific complications are present.