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    Alternative surgical approach for the management of uterine prolapse in young women: Preliminary results
    (Wiley-Blackwell, 2013) Karatayli, Rengin; Balci, Osman; Gezginc, Kazim; Yildirim, Pinar; Karanfil, Fikriye; Acar, Ali
    AimTo demonstrate an alternative surgical approach for the management of uterine prolapse in young women by a technique that was previously defined for post-hysterectomy vaginal vault suspension in published work and also to demonstrate successful operative results. MethodsThe study population consisted of 12 women aged 28-41 years who had stage 4 uterine prolapse and who were surgically treated by abdominal hysteropexy using autogenous rectus fascia strips. Operative results and postoperative follow-up Pelvic Organ Prolapse Quantification and Prolapse Quality of Life results were recorded. ResultsMean age of patients was 35.54.1 years (range, 28-41). Mean parity in the study group was 2.6 +/- 1.0 (range, 1-5). Mean operation time was 32.0 +/- 5.2min (range, 25-42). All patients were discharged on the postoperative 3rd day and no complications were observed postoperatively. Mean follow-up period was 20 +/- 7.0 months (range, 12-36). All of the patients had complete remission for uterine prolapse and none of the patients had complaints related to the operation. ConclusionAbdominal hysteropexy operation using rectus fascia strips provides a safe and alternative approach for the management of uterine prolapse in young women who desire to preserve their uterus. But further analysis is needed to confirm our results.
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    The comparison of the degree of apoptosis in ovaries and fallopian tubes between two different surgical interventions for tubal ligation: A rat model
    (Galenos Yayincilik, 2018) Mumusoglu, Sezcan; Hacivelioglu, Servet; Sokmensuer, Lale Karakoc; Karatayli, Rengin; Suzer, Aysegul; Kaymaz, Figen
    Objective: To compare the degree of apoptosis in ovaries and tubal epithelium observed secondary to tubal ligation either by Pomeroy's method or bipolar electrocauterization in a rat model. Material and Methods: A total of 24 female Sprague-Dawley rats were randomly assigned into 3 study groups: control (n=8), Pomeroy (n=8), and the electrocauterization group (n=8). Apoptotic cells were detected on the primary, secondary, tertiary follicles of the ovaries, and on the tubal epithelium using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling. The apoptotic index was calculated for each group by the percentage of the stained cells. Results: The apoptotic index of tubal epithelium was significantly higher in the bipolar electrocauterization group compared with the control and Pomeroy groups (3.1 +/- 0.8 vs. 1.4 +/- 1.0, p=0.018 and 2.0 +/- 1.2, p=0.03, respectively) whereas there was no significant difference between Pomeroy's method and the control group. The apoptotic index of primary follicles was higher in the bipolar electrocauterization group compared with the control and Pomeroy's method groups (3.4 +/- 0.5 vs. 1.2 +/- 0.4, p<0.001 and 1.8 +/- 0.8, p=0.005, respectively), but there was no significant difference between Pomeroy's method and the control group. The apoptotic index of secondary and tertiary follicles was similar for each group. Conclusion: Pomeroy's technique, as a permanent contraception method, is associated with lower apoptotic index on ovary and fallopian tube when compared with bipolar electrocauterization.