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Öğe Deep femoral artery branching by MDCT in a Turkish population and its potential clinical implications(Soc Anatomica Espanola, 2023) Keles, Ali; Yilmaz, Mehmet T.; Kadiyoran, Cengiz; Saygin, Duygu A.The deep femoral artery and its branches are vital for the arterial circulation of the lower ex-tremity. The aim of the current study is to obtain morphometric and morphological data on the deep femoral artery and its branches and to in-vestigate their clinical importance in the Turkish population. Morphometric measurements of the deep femoral artery and femoral artery were per-formed. The diameters of the femoral artery and deep femoral artery were measured in the axial plane. Classification was made according to the size of these diameters. A morphological classifi- cation was obtained by examining the variations of the deep femoral artery branches. The distance from the origin of the deep femo-ral artery to the midpoint of the inguinal ligament was 39.56 & PLUSMN; 8.52 mm, and the distances from the origin of the lateral circumflex femoral artery to the medial circumflex femoral artery were 17.15 & PLUSMN; 4.79 mm and 12.52 & PLUSMN; 4.58 mm, respectively. The study results show that there was a sig-nificant difference between genders in terms of the diameters measured. In the classification made by using the diameters, Type D (39%) had the highest rate, whereas Type C had the lowest rate (7.3%). According to the morphological clas- sification, Type I (52.1%) was the most common in all individuals, and Type V and Type VII (2.3%) were the least common. Our study includes both morphometric and morphological information about the femoral artery and deep femoral ar-tery of the Turkish population. We consider that the current study will be useful for cardiologists, interventional radiologists, orthopedists, and re-gional surgeons in clinical practice.Öğe The Effectiveness of Crataegus orientalis M Bieber. (Hawthorn) Extract Administration in Preventing Alveolar Bone Loss in Rats with Experimental Periodontitis(Public Library Science, 2015) Hatipoglu, Mukerrem; Saglam, Mehmet; Koseoglu, Serhat; Koksal, Ekrem; Keles, Ali; Esen, Haci HasanThe purpose of this animal study was to evaluate the effects of hawthorn (Crataeus orientalis M Bieber.) extract on serum oxidative status and alveolar bone loss in experimental periodontitis. Twenty-seven Wistar rats were assigned to one of the following groups: nonligated+placebo (saline) (NL, n = 9), ligature only+placebo (saline) (LO, n = 9), and ligature and treated with hawthorn extract in saline (H, n = 9) (100 mg/kg orogastrically, once a day for 11 days). Periodontitis was induced by submerging a 4/0 silk ligature in the sulcus of the mandibular right first molars of rats, and the animals were sacrificed after 11 days. Micro-CT examinations were performed for linear and volumetric parameter assessment of alveolar bone. Periodontal tissues were histopathologically examined to assess the differences among the study groups. Levels of serum total antioxidant status (TAS)/total oxidant status (TOS), and oxidative stress index (OSI) were also analyzed. Alveolar bone loss was significantly reduced by hawthorn administration compared to LO group (p<0.05). The number of inflammatory cells and osteoclasts in the LO group was significantly higher than that of the NL and H groups (p<0.05). The number of osteoblasts in the LO and H groups was significantly higher than that of the NL group (p<0.05). TOS and OSI levels were significantly reduced in H group compared to LO group (P < 0.05) and TAS levels were similar in H and NL group (p < 0.05). Hawthorn extract showed inhibitory effect on periodontal inflammation and alveolar bone loss by regulating TAS, TOS and OSI levels in periodontal disease in rats when administered systemically.Öğe The Effectiveness of Crataegus orientalis M Bieber. (Hawthorn) Extract Administration in Preventing Alveolar Bone Loss in Rats with Experimental Periodontitis(Public Library Science, 2015) Hatipoglu, Mukerrem; Saglam, Mehmet; Koseoglu, Serhat; Koksal, Ekrem; Keles, Ali; Esen, Haci HasanThe purpose of this animal study was to evaluate the effects of hawthorn (Crataeus orientalis M Bieber.) extract on serum oxidative status and alveolar bone loss in experimental periodontitis. Twenty-seven Wistar rats were assigned to one of the following groups: nonligated+placebo (saline) (NL, n = 9), ligature only+placebo (saline) (LO, n = 9), and ligature and treated with hawthorn extract in saline (H, n = 9) (100 mg/kg orogastrically, once a day for 11 days). Periodontitis was induced by submerging a 4/0 silk ligature in the sulcus of the mandibular right first molars of rats, and the animals were sacrificed after 11 days. Micro-CT examinations were performed for linear and volumetric parameter assessment of alveolar bone. Periodontal tissues were histopathologically examined to assess the differences among the study groups. Levels of serum total antioxidant status (TAS)/total oxidant status (TOS), and oxidative stress index (OSI) were also analyzed. Alveolar bone loss was significantly reduced by hawthorn administration compared to LO group (p<0.05). The number of inflammatory cells and osteoclasts in the LO group was significantly higher than that of the NL and H groups (p<0.05). The number of osteoblasts in the LO and H groups was significantly higher than that of the NL group (p<0.05). TOS and OSI levels were significantly reduced in H group compared to LO group (P < 0.05) and TAS levels were similar in H and NL group (p < 0.05). Hawthorn extract showed inhibitory effect on periodontal inflammation and alveolar bone loss by regulating TAS, TOS and OSI levels in periodontal disease in rats when administered systemically.Öğe Morphometric analysis of cavitas glenoidalis with multidedector CT(Soc Anatomica Espanola, 2023) Keles, Ali; Yilmaz, Mehmet T.; Ozbek, Orhan; Saygin, Duygu A.; Seker, MuzafferThe glenoid cavity is a sliced egg-shaped joint surface located on the lateral margin of the scapula to form the shoulder joint. Recognition of variations in shape and dimensions of the glenoid cavity is important for a better comprehension of joint-associated diseases, especially in total shoulder arthroplasty procedures. The aim of this study was to perform morphometric measurements on the glenoid cavity. Glenoid cavities of 391 individuals (197 males [50.4%], 194 females [49.6%]) were reviewed by using Multi-detector Computed Tomography. The maximum length and maximum width of glenoid cavities, as well as the width, depth and circumference at the notch level were measured, and the index value was calculated. The glenoid cavity shapes were typed as pear, inverted comma and oval type. Furthermore, the metric values that provide the best differentiation between genders were identified through ROC analysis.The pear glenoid cavity type was detected in 53.2%, inverted comma type was detected in 28.4%, and oval type was detected in 18.4% of cases. In all of our morphometric measurements, male values were higher than female values, and there was significant difference between them. Results of ROC analysis revealed significant mea- surements for the maximum length and maximum width measurements of the glenoid for gender determination. Morphometric information of the glenoid cavity can be useful in order to increase clinical success in case of Bankart lesion, rotator cuff disease, and osteochondral defect. Recognition of different shapes and dimensions of the glenoid cavity is essential for the design of the glenoid component, especially for total shoulder arthroplasty procedure. We believe that the data obtained in our study would be useful for prosthesis designers and orthopaedic surgeons.