Yazar "Kuru, Murat" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • Küçük Resim
    Öğe
    Bilateral pnömotoraksın eşlik ettiği travmatik pnömomediastinum: Olgu sunumu
    (2014) Apilioğulları, Burhan; Kuru, Murat; Ceran, Sami
    Mediastende hava bulunması Pnömomediastinum olarak tanımlanmaktadır. Şiddetli künt toraks travmalarından sonra % 10 oranında pnömomediastinum görüldüğü bildirilmiştir. Bu tablo kendiliğinden oluşabileceği gibi, travmatik olarak da oluşabilmektedir. Kendiliğinden oluşan ve spontan pnömomediastinum olarak da ifade edilen şekli, genellikle genç erkeklerde ve nadir görülür. Travmatik pnömomediastinum ise, genellikle toraks travmaları ve servikal travmalar sonucunda herkesde görülebilmektedir. Kliniği değişkenlik gösteren pnömomediastinumun tanısında göğüs ağrısı, nefes darlığı ve sub- kutan amfizem semptomlarının üçünün olması önemlidir. Biz toraks travması neticesinde bilateral pnömotoraksın eşlik ettiği pnömomediastinumlu bir hasta sunuyoruz.
  • Küçük Resim Yok
    Öğe
    Comparison of the effects of alpha lipoic acid and dexpanthenol in an experimental tracheal reconstruction animal model
    (Saudi Med J, 2023) Kuru, Murat; Altinok, Tamer; Metin, Bayram; Esen, Haci Hasan
    Objectives: To investigate the positive effects of intraperitoneal administration of alpha-lipolic acid (ALA) and dexpanthenol (DXP) on wound healing after tracheal surgery in rats. Methods: The study was carried out at Necmettin Erbakan University, Konya, Turkey, from January 2014-2019. A total of 30 healthy and adult Sprague-Dawley type female rats were included in the study. For the experiment, rats were randomly divided into 3 groups: ALA group (n=10), DXP group (n=10), and control group (n=10). After trachea surgery, 100 mg/kg/day ALA was given to group ALA and 100 mg/kg/day intraperitoneal DXP to group DXP for 15 days, and the rats were sacrificed on the 21st day. The excised tracheal sections were evaluated and graded for inflammatory cell infiltration, angiogenesis, fibroblast proliferation, collagen deposition, and epithelial regeneration to evaluate wound healing. Results: Inflammation was found to be less in both the ALA and DXP groups. With the Mann-Whitney test, it was determined that inflammation was less in the ALA group than in the DXP group (C-D [p=0.097] and C-A [p=0.024]). On the other hand, no statistically significant difference was found in epithelial regeneration (p=0.574; >0.05), angiogenesis (p=0.174; >0.05), fibroblast proliferation, and collagen deposition (p=0.102; >0.05). Conclusion: Alpha-lipolic acid injected intravenously after tracheal reconstruction in patients can prevent restenosis by reducing inflammation without adversely affecting wound healing
  • Küçük Resim Yok
    Öğe
    Comparison of the effects of alpha lipoic acid and dexpanthenol in an experimental tracheal reconstruction animal model
    (Saudi Med J, 2023) Kuru, Murat; Altinok, Tamer; Metin, Bayram; Esen, Haci Hasan
    Objectives: To investigate the positive effects of intraperitoneal administration of alpha-lipolic acid (ALA) and dexpanthenol (DXP) on wound healing after tracheal surgery in rats. Methods: The study was carried out at Necmettin Erbakan University, Konya, Turkey, from January 2014-2019. A total of 30 healthy and adult Sprague-Dawley type female rats were included in the study. For the experiment, rats were randomly divided into 3 groups: ALA group (n=10), DXP group (n=10), and control group (n=10). After trachea surgery, 100 mg/kg/day ALA was given to group ALA and 100 mg/kg/day intraperitoneal DXP to group DXP for 15 days, and the rats were sacrificed on the 21st day. The excised tracheal sections were evaluated and graded for inflammatory cell infiltration, angiogenesis, fibroblast proliferation, collagen deposition, and epithelial regeneration to evaluate wound healing. Results: Inflammation was found to be less in both the ALA and DXP groups. With the Mann-Whitney test, it was determined that inflammation was less in the ALA group than in the DXP group (C-D [p=0.097] and C-A [p=0.024]). On the other hand, no statistically significant difference was found in epithelial regeneration (p=0.574; >0.05), angiogenesis (p=0.174; >0.05), fibroblast proliferation, and collagen deposition (p=0.102; >0.05). Conclusion: Alpha-lipolic acid injected intravenously after tracheal reconstruction in patients can prevent restenosis by reducing inflammation without adversely affecting wound healing
  • Küçük Resim Yok
    Öğe
    Diagnostic value of platelet-to-lymphocyte ratio in patients with solitary pulmonary nodules
    (Termedia Publishing House Ltd, 2022) Kuru, Murat; Altinok, Tamer
    Introduction: Nodules detected in the lung parenchyma should be considered as malignant until proven otherwise, and the necessary tests should be performed for diagnosis.Aim: To calculate the preoperative platelet-to-lymphocyte ratio (PLR) in patients with malignant lung nodules and to investigate the diagnostic value of this ratio in determining the histopathology of the nodule.Material and methods: Ninety-one patients who were operated on for a malignant nodule in the lung between September 2010 and September 2020 were included in the study. The PLR was calculated by dividing the absolute platelet count by the absolute lymphocyte count. These values were compared with the histopathological diagnoses of the resected tumor tissue. Patients with primary lung malignancy were classified as group 1 (n = 54), and lung metastases of other organs were classified as group 2 (n = 37).Results: The mean PLR was 127.27 +/- 46.82 in the first group and 183.56 +/- 93.49 in the second group. There was a statistically significant difference in PLR values between the two groups, and PLR was higher in group 2. There was no statistically significant difference between the two groups in terms of lymph node positivity, nodule size and SuvMax values. A moderately strong, significant and same-sided correlation was observed between nodule size and SuvMax values in the first group of patients (r = 0.48, p = 0.001)Conclusions: PLR values less than 89.41 indicate that the histopathological result may be a lung-derived malignancy. However, in cases where the PLR is detected above 165.6, it would be appropriate to interpret another previously detected malignancy as metastasis to the lung.
  • Küçük Resim Yok
    Öğe
    Endoscopic thoracic sympathectomy: Early, mid-term and late outcomes and patient satisfaction Outcomes of endoscopic thoracic sympathectomy and satisfaction
    (Bayrakol Medical Publisher, 2021) Kuru, Murat; Altinok, Tamer
    Aim: This study presents the outcomes and patient satisfaction after endoscopic thoracic sympathectomy (ETS) applied to patients unresponsive to medical treatment. Material and Methods: Sixty-one patients who underwent ETS for axillary/palmar hyperhidrosis from June 2010 to June 2019 were retrospectively evaluated. Data were collected from patient charts and files. Patient satisfaction and preoperative and postoperative changes in patient's social lives were assessed over the phone. Results: The mean age of the included 61 patients was 23.2 +/- 5.63 years, the mean length of the postoperative follow-up period was 27.3 months. Moderate-severe compensatory hyperhidrosis was observed in 2 patients. A significant majority of patients were satisfied with the surgery and they stated that would recommend it to others. The loss of self-confidence in the preoperative period was significantly restored in the postoperative period. Discussion: ETS with the incision of the sympathetic chain at the T3-T4 level is associated with significant reductions in pain severity and compensatory hyperhidrosis and with significant patient satisfaction in the postoperative period. It should always be remembered that the likelihood of developing compensatory hyperhidrosis is high in patients over 30 years of age and that it occurs after the first postoperative month.
  • Küçük Resim Yok
    Öğe
    Surgical Treatment of Acute Mediastinitis Due to Fish Bone
    (Derman Medical Publ, 2017) Kuru, Murat; Altinok, Tamer
    Acute mediastinitis is a serious condition that needs to be treated quickly. A 66-year-old female patient was admitted to the emergency department with fever and confusion. In her medical history she said that she coughed after eating fish 11 days earlier and a fish bone returned to her mouth one day before the admission to hospital. Her thorax CT scan showed air and high-density liquid collections in the mediastinal compartments. She was hospitalized with a diagnosis of mediastinitis. An endoscopy performed before the operation to examine the esophagus revealed a small necrotized area. The patient underwent surgery and the abscess was debrided after preoperative preparation. She was discharged on the postoperative 35th day after an intensive course of treatment.