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    Comparison of the body compositions in obese and nonobese individuals: Can learning body compositions motivate losing weight?
    (Wolters Kluwer Medknow Publications, 2017) Kutlu, R.; Cihan, F. G.
    Background: Obesity is one of the leading preventable causes of death worldwide. Objective: To compare body compositions in obese and nonobese individuals. Methods: This cross-sectional study constituted of 428 individuals. Body compositions were determined using the Tanita. Results: Of all the participants, 300 (70.1%) were female. The prevalence of overweight and obesity was 30.8% and 47.7%, respectively. Having low educational level, female gender, not working, being married, and nonsmoker significantly increased more in obese than nonobese (P < 0.001). Total body water, visceral fat accumulation, body mass index, resting metabolic rate, fat-free mass, bone mass, and muscle mass were significantly higher in obese when compared to those with nonobese (P < 0.001). Thirteen percent of the participants were thinking of changing their diet and lifestyle to lose weight at the beginning. After learning their body compositions, the rate increased to 60% who decided to modify their lifestyle and asked for help to lose weight. This behavior change was significant in especially the overweighted participants (P = 0.025). Conclusion: The changes in body composition are associated with obesity and increased risk for certain cancers, cardiovascular disease, type 2 diabetes mellitus. Learning the health risks can motivate losing weight. Multicentered studies can be illuminating different cultural factors about obesity.
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    Effects of mandatory salt iodization on breast milk, urinary iodine concentrations, and thyroid hormones: is iodine deficiency still a continuing problem?
    (Springer, 2019) Ozberk, D. Isiklar; Kutlu, R.; Kilinc, I.; Kilicaslan, A. O.
    PurposeTo investigate whether mandatory use of iodized salt in Turkey, since 1999 has sufficient effects on pregnant women and their newborns' urinary iodine concentrations (UIC), maternal and newborns' thyroid function tests and breast milk iodine concentrations (BMIC).MethodsThis cross-sectional analytical-type study was conducted in an obstetrics and gynecology hospital in Konya, Turkey. One hundred and seven pregnant women and their 107 full-term newborns were included into the study. Levels of pregnant women and their newborns' UIC, thyroid-stimulated hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroglobulin (Tg), and BMIC were studied.ResultsOf 107 women with term pregnancy, mean TSH value and hypothyroidism frequency were found as 2.341.33 mIU/L and 18.7%, respectively. Cord blood TSH level was found higher (10 mIU/L) in five newborns. Accordingly, the incidence of transient congenital hypothyroidism was 4.7% (5/107). Tg levels were observed to be higher in 50.5% of newborns and 22.4% of pregnant women. Frequency of iodized salt use in pregnancies was detected as 96.3% in general population, 97.5% in urban, and 92.9% in rural areas. Of pregnancies and newborns, 57.9 and 53.3% were found to have deficient urinary iodine, respectively, and BMIC deficiency was detected as 52.0%. There was a significant positive correlation between pregnant women's UIC, and newborns' UIC and BMIC.Conclusions p id=Par4 Despite the effective struggle with iodine deficiency and salt iodination control program in Konya, we concluded that iodine deficiency still persists as a significant problem in pregnancies.
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    Evaluation of depression and quality of life in patients with obstructive sleep apnea syndrome
    (Wolters Kluwer Medknow Publications, 2016) Yosunkaya, S.; Kutlu, R.; Cihan, F. G.
    Background: Sleep fragmentation, repetitive hypoxemia during sleep, excessive sleepiness during the day, lack of concentration, memory loss, depression, decreased libido, and impotence are the characteristics of obstructive sleep apnea syndrome (OSAS) that may impair quality of life (QOL). This study aimed to investigate the QOL and factors that may affect QOL in people with different OSAS severity and without sleep apnea. Methods: This was an analytical cross-sectional study. Polysomnography was performed on 200 people. Those detected as having nonapnea and mild-moderate-severe OSAS were administered the Epworth sleepiness scale, Beck Depression Inventory, and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) scale. Results: According to the apnea-hypopnea index, 36 people (18.0%) were in the nonapnea-hypopnea group, 28 (14.0%) in the mild OSAS group, 63 (31.5%) in the moderate OSAS group, and 73 people (36.5%) were in the severe OSAS group. Depression was present in 31 people (15.5%) who participated in the study. The nonapnea-hypopnea group comprised 12.9% of those with depression, mild OSAS group comprised 16.1%, moderate OSAS group comprised 22.6%, and severe OSAS group had 48.4% of the depressed subjects. Beck depression scores showed a significant positive correlation with the Epworth scale (t 90% SaO2) (r = 0.285, P 0.001 and r = 0.283, P 0.001, respectively). The mean scores of WHOQOL-BREF subgroups' physical health (P 0.001), psychological health (P 0.001), social relations (P 0.001), and the environmental area (P 0.001) in those with depression were statistically significantly lower than those without depression. QOL was significantly associated with the presence of OSAS (P = 0.008). Conclusion: Decreased deep sleep duration, increased arousal index, and a high ratio of sleep duration with oxygen saturation below 90% to the duration of the entire sleep period increase daytime sleepiness and depressive symptoms in those with OSAS; thus, disrupting general health and QOL.
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    Restless Legs Syndrome and Quality of Life in Chronic Hemodialysis Patients
    (Wolters Kluwer Medknow Publications, 2018) Kutlu, R.; Selcuk, N. Y.; Sayin, S.; Kal, O.
    Context: Restless legs syndrome (RLS) is a sensorimotor disorder that often has a profound impact on sleep and one of the most troublesome conditions experienced in hemodialysis patients. Aims: The aim of study was to search frequency of RLS and effects of RLS on quality of life (QoL) in chronic hemodialysis patients. Settings and Design: Chronic hemodialysis patients of classical hemodialysis units were chosen. Length of the study was approximately 1 year. Subjects and Methods: Two hundred and thirty-seven patients were investigated. RLS was diagnosed using to international the RLS questionnaire. The International RLS (IRLS) rating scale was used to calculate RLS severity. QoL was assessed using the World Health Organization QoL brief version (WHOQOL-BREF) instrument. Statistical Analysis Used: Student's t-test, Chi-square test or Fisher's exact test, Bonferroni correction for multiple comparisons, and Pearson or Spearman correlation analysis were used. Significance level was P < 0.05. Results: The overall prevalence of RLS according to the four essential criteria was 18.6% (n = 44). According to IRLS, 22.7% of the patients with RLS were mild (n = 10), 63.6% were moderate (n = 28), and 13.7% were severe (n = 6). The parameters of QoL were compared in RLS-positive and negative patients. There was no significant difference in psychological health (P = 0.971), social relationships (P = 0.462), and environment (P = 0.483) between two groups. Only the physical health scores were higher in without RLS than patients with RLS (P = 0.027). Conclusions: This study revealed that the frequency of RLS among chronic hemodialysis patients is 18.6% and RLS leads to physical life quality disturbances.