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Ankilozan spondilit ile ilişkili üveit olgularında klinik seyir ve bulgular
(2013) Oltulu, Refik; Yumak Erkoç, Hanife; Şatırtav, Günhal; Okka, Mehmet
Amaç: Ankilozan spondilit (AS) ile ilişkili üveit tanısı almış olguların klinik seyir ve bulgularının incelenmesi Yöntemler: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Göz Hastalıkları Anabilim Dalı, uvea birimi tarafından Mayıs 2009-Haziran 2012 tarihleri arasında AS ile ilişkili üveit tanısı almış olgular retrospektif olarak incelendi. Olguların sosyodemografik ve klinik özellikleri değerlendirildi. Bulgular: Toplam 13 hastanın 17 gözü çalışmaya dahil edildi. Olgular dokuz erkek (%69,2), dört kadından (%30,8) oluşmakta idi. Ortalama başvuru yaşları 38,549,61(28-63) yıl idi. Dört olguda iki taraflı tutulum (%30,8) tespit edildi. İzlem süreleri 17,4611,86 ay (3-36 ay) idi. Ortalama atak sayısı 1,150,37(1-2) idi. Üç gözde (%17,6) ön üveite eşlik eden arka segment bulguları izlendi. Bir olguda (%7,7) arka yapışıklık, bir olguda (%7,7) katarakt, iki olguda (%15,4) kistoid makula ödemi, bir olguda epiretinal membran (%7,7) tespit edildi. Hastaların sonuç görme keskinlikleri ortalama 0,9750,07 (0,2-1,0) olarak izlendi. Sonuç: AS ile ilişkili ön üveit olgularında zamanında ve doğru bir yaklaşım tarzı ile prognoz iyidir. Bu olgularda arka segment komplikasyonlarının da gelişebileceği unutulmamalı, tedavi ve takipleri romatoloji kliniği ile işbirliği içinde yapılmalıdır.
The Causes and Frequency of Monocular and Binocular Blindness in Adults Applying to the Health Committee of a University Hospital in Central Anatolia
(Galenos Publ House, 2021) Mirza, Gunsu Deniz; Okka, Mehmet; Mirza, Enver; Belviranli, Selman
Objectives: The aim of this study was to investigate the frequency of blindness and the pathologies that cause blindness in the Konya province of Turkey. Materials and Methods: The records of individuals over 18 years of age who applied to the health committee of Meram School of Medicine Hospital between January 2015 and December 2018 were evaluated retrospectively. Results: After reviewing the records of 4,268 applicants, a total of 222 applicants were included in the study (159 patients with monocular blindness, 63 patients with binocular blindness). The most common causes of monocular blindness were optic atrophy (13%), amblyopia (11%), and phthisis bulbi (10%). The most common causes of binocular blindness were retinitis pigmentosa (28%), proliferative diabetic retinopathy (13%), and unoperated cataract (11%). The frequency of monocular blindness was 3.7% (95% confidence interval [CI]: 3.2-4.3%) and binocular blindness was 1.5% (95% CI: 1.1-1.9%) in the sample. The frequency of blindness increased with age, with a positive correlation between mean age and blindness (p=0.002). Monocular blind applicants had a significantly lower mean age than binocular blind applicants (48.8 +/- 13.3 vs. 55.0 +/- 13.1 years, p=0.002) and binocular blind women had a significantly higher mean age than binocular blind men (62.7 +/- 16.0 vs. 53.2 +/- 11.7 years, p=0.023). The prevalence of monocular and binocular blindness was significantly higher in men than women (p=0.032). Conclusion: The results of this study show that many of the pathologies that cause blindness are preventable or treatable, and that blindness is associated with age.
Dirençli Glokom Olgularında Transskleral Diod Lazer Siklofotokoagülasyon
(2012) Bitirgen, Gülfidan; Okka, Mehmet; Bozkurt, Banu; Doğru, İsmail; Kerimoğlu, Hürkan; Öztürk Turgut, Banu; Kamış, Ümit
Amaç: Medikal veya cerrahi tedavilerle kontrol edilemeyen ileri evre glokom olgularında transskleral diod lazer siklofotokoagülasyon (TSDLS) uygulamasının güvenilirliğinin ve etkinliğinin değerlendirilmesi. Gereç ve Yöntem: 2009-2011 yılları arasında TSDLS tedavisi uygulanan olgular retrospektif olarak incelendi. Tedavi öncesi ve sonrası göz içi basıncı (GİB) değerleri, görme keskinlikleri, kullanılan antiglokomatöz tedavi sayıları ve komplikasyonlar kaydedildi. TSDLS başarı kriteri, son kontrolde GİB ölçümünün 6-22 mmHg (ilaçlı ya da ilaçsız) olması olarak belirlendi. Sonuçlar: Çalışmaya 37 olgunun 37 gözü dahil edildi. Olguların yaş ortalaması 61,7317,13 yıl (19-80 yıl) ve ortalama takip süresi 8,065,81 ay (3-22 ay) idi. Tedavi öncesi ortalama GİB değerleri 38,688,94 mmHg, tedavi sonrası 2. haftada 26,4611,34 mmHg (p 0,01) ve son kontrolde 24,9710,84 mmHg (p0,01) idi. Olguların %40,5’inde son kontrolde ölçülen GİB değerleri 22 mmHg ve altındaydı. Göz başına ortalama diod lazer seans sayısı 1,480,73 olarak saptanırken birden fazla tedavi seansı gerektiren olgu sayısı 13 (%35,1) idi. Kullanılan antiglokomatöz tedavi etken madde sayısı tedavi öncesi 3,141,18 iken tedavi sonrası 2,761,23 olarak saptandı. Takip süresince olguların hiçbirinde fitizis bulbi ya da persistan hipotoni gelişmedi. Tart›flma: TSDLS uygulaması, dirençli glokom olgularında GİB düşürülmesinde etkin ve güvenilir bir tedavi yöntemidir. Aynı zamanda antiglokomatöz tedavi kullanımında azalma sağlayarak hastaların tedaviye uyumunu ve yaşam kalitesini artırmaktadır.
Diurnal Variation of Anterior Chamber Flare
(Turkish Ophthalmological Soc, 2015) Adam, Mehmet; Okka, Mehmet; Ozturk, Banu Turgut; Bozkurt, Banu; Kerimoglu, Hurkan; Pekel, Hamiyet; Okudan, Suleyman
Objectives: To investigate the ideal time and reproducibility of anterior chamber flare measurements. Materials and Met-hods: Anterior chamber flare measurements were performed with laser flaremetre device at 8 am to 45 volunteers and these measurements were repeated on the same day at 12 pm and 4 pm. Results: Twenty- five (55.5%) of the volunteers were women and 20 (44.5%) were men; mean age was 28.67 +/- 7.40 (18- 49) years. The mean anterior chamber flare measurements taken following the ophthalmologic examination were 5.94 +/- 1.41 foton/msn at 8 am, 5.65 +/- 1.45 foton/msn at 12 pm, and 5.79 +/- 1.20 foton/msn at 4 pm. No statistical difference was found between the measurements (p=0.08). Subgroup analysis according to eye color, revealed no significant difference between flare measurements in brown, hazel, and green eyes (p=0.21). Correlation analysis demonstrated association between age and all flare measurements within the day (r=0.24, p=0.03; r=0.41, p=0.01, r=0.27, p=0.01). Conclusion: No significant diurnal change was detected in the flare measurements of our study subjects but positive correlation with age was observed. Hence, all flare measurements within a day are reliable and have high repeatability in healthy subjects.
Dry eye disease and ocular surface characteristics in patients with keratoconus
(Wolters Kluwer Medknow Publications, 2022) Mirza, Enver; Oltulu, Refik; Oltulu, Pembe; Mirza, Gunsu D.; Okka, Mehmet
PURPOSE: The purpose of this study is to investigate the ocular surface alterations in patients with mild or severe keratoconus (KC). METHODS: A total of 80 participants were included in the study. The corneal topography was performed on each participant using Pentacam and the grouping was done accordingly. The patients with Kmax >= 52.0 D (severe KC) were considered Group 1 (n = 28), the patients with Kmax >= 47.2 and <52.0 D (mild KC) were considered Group 2 (n = 30). Healthy control participants with Kmax <47.2 D were considered Group 3 (n = 22). Tear breakup time (TBUT), Schirmer-I test, ocular surface disease index (OSDI) questionnaire, and conjunctival impression cytology (CIC) were evaluated among the groups. RESULTS: The mean values of TBUT and Schirmer-I test were significantly lower (P = 0.012, P = 0.012) and the mean scores of OSDI and CIC were significantly higher (P = 0.006, P < 0.001) in Group 1 and Group 2 than in Group 3. The mean values of TBUT and Schirmer-I test were lower and the mean scores of OSDI and CIC were higher in Group 1 than in Group 2 but the differences were insignificant (P > 0.05 for all). CONCLUSION: These results indicated that the tests associated with dry eye disease are correlated with KC. Tear film alterations and goblet cell loss are higher in severe KC.
The Effect of Dehydration and Fasting on Corneal Biomechanical Properties and Intraocular Pressure
(Lippincott Williams & Wilkins, 2016) Oltulu, Refik; Satirtav, Gunhal; Ersan, Ismail; Soylu, Erkan; Okka, Mehmet; Zengin, Nazmi
Purpose: To evaluate the changes in corneal biomechanical properties and intraocular pressure (IOP) during fasting period in healthy subjects. Methods: Seventy-two eyes of 72 fasting subjects (study group), and 62 eyes of 62 nonfasting subjects (control group) were enrolled in this prospective study undertaken at a single university hospital. All subjects underwent complete ophthalmologic examination including ocular biomechanical evaluation with ocular response analyzer. Ocular response analyzer measurement was performed on the right eyes of the subjects between 5.00 and 6.00 PM after approximately 14 hr of fasting for the study group and after a nonfasting period for the control group. The corneal hysteresis, corneal resistance factor, mean corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) values were measured with a patented dynamic bidirectional applanation process. Results: Goldmann-correlated IOP and IOPcc measurements in the study group and the control group were found as 13.8 +/- 2.8 mm Hg, 14.6 +/- 2.6 mm Hg and 16.3 +/- 2.2 mm Hg, 15.7 +/- 2.4 mm Hg, respectively. There was statistically significant difference within the two groups in IOPg and IOPcc (P < 0.001). In addition, corneal hysteresis and corneal resistance factor significantly decreased in study group compared with control group (P < 0.001, P = 0.012, respectively). Conclusion: Prolonged fasting causes a significant decrease in IOPg, IOPcc, corneal hysteresis, and corneal resistance factor in healthy subjects, altering the biomechanical properties of the cornea.
Effect of Eye Rubbing on Corneal Biomechanical Properties and Intraocular Pressure
(Turkish Ophthalmological Soc, 2014) Oltulu, Refik; Donbaloglu, Meryem; Satirtav, Gunhal; Okka, Mehmet; Ozkagnici, Ahmet
Objectives: To determine whether corneal biomechanical properties and intraocular pressure (IOP) are affected by eye rubbing. Materials and Methods: Healthy individuals, aged between 15 and 50 years, without any ocular pathological signs were included. Corneal biomechanical parameters, Goldmann-equivalent intraocular pressure (IOPg), corneal-compensated intraocular pressure (IOPcc), corneal resistance factor (CRF), and corneal hysteresis (CH) values were measured using an ocular response analyzer (ORA). Measurements were taken at baseline and immediately after 30 seconds of eye rubbing. ORA parameters before and after eye rubbing were analyzed using student's t test. A p-value less than 0.05 was considered statistically significant. Results: We included eighty-one eyes of 53 individuals with a mean age of 32 +/- 10.11(15-50) years. Before eye rubbing, the mean measurement values were as follows: CH 10.93 +/- 1.69 mmHg, CRF 10.82 +/- 1.78 mmHg, IOPg 15.76 +/- 3.18 mmHg, and IOPcc 15.74 +/- 2.69 mmHg. The mean values after eye rubbing were: CH 11.11 +/- 1.52 mmHg, CRF 10.54 +/- 1.56 mmHg, IOPg 14.32 +/- 3.10 mmHg, and IOPcc 14.20 +/- 2.77 mmHg. The decrease in CRF, IOPg, and IOPcc was statistically significant, while the change in CH was found to be statistically insignificant. Conclusion: CRF, IOPg, and IOPcc decreased significantly after eye rubbing and this should be considered before taking any ORA measurements and interpreting the results.
Effect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzer
(Taylor & Francis Ltd, 2015) Oltulu, Refik; Satirtav, Gunhal; Altunkaya, Orhan; Bitirgen, Gulfidan; Okka, Mehmet
Purpose: This observational study aims to investigate the effects of tropicamide (0.5%) on corneal biomechanical properties, with the ocular response analyzer (ORA), in healthy individuals. Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) measurements of 38 (21 female and 17 male) healthy individuals, before and after 30 min of 0.5% tropicamide instillation, were performed by using the ORA. Results: The mean CH, CRF, IOPg and IOPcc measurements of the eyes were 10.2 +/- 1.9 mmHg, 10.3 +/- 2.1 mmHg, 15.7 +/- 3.4 mmHg, 16.4 +/- 3.3 mmHg pre-tropicamide, and 10.4 +/- 1.7 mmHg, 10.3 +/- 2.1 mmHg, 15.3 +/- 3.4 mmHg, 15.8 +/- 2.7 mmHg post-tropicamide, respectively. The differences between the pre- and post-tropicamide measurements of the eyes were insignificant (p = 0.184, p = 0.659, p = 0.294, p = 0.150, respectively; paired t-test). Conclusions: A tropicamide instillation does not lead to significant changes in the corneal biomechanical properties. Therefore, it can be used safely in disease, i.e. in the diagnosis and follow-up ORA as it does not cause any change.
The Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Obstructive Sleep Apnea Syndrome
(Hindawi Ltd, 2013) Adam, Mehmet; Okka, Mehmet; Yosunkaya, Sebnem; Bozkurt, Banu; Kerimoglu, Hurkan; Turan, Meydan
Aim. To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with obstructive sleep apnea syndrome (OSAS) by optical coherence tomography (OCT). Materials and Method. We studied 43 new diagnosed OSAS patients and 40 healthy volunteers. Patients underwent an overnight sleep study in an effort to diagnose and determine the severity of OSAS. RNFL analyses were performed using Stratus OCT. The average and the four-quadrant RNFL thickness were evaluated. Results. There was no difference between the average and the four-quadrant RNFL thickness in OSAS and control groups. There was no correlation between apnea-hypopnea index and intraocular pressure. Body mass index of patients with moderate and severe OSAS was significantly higher in patients with mild OSAS. Conclusion. Mean RNFL thickness did not differ between the healthy and the OSAS subjects, however, the parameters were more variable, with a larger range in OSAS patients compared to controls.
Evaluation of the Systemic Inflammation in Patients with Pterygium: Monocyte-to- High-Density Lipoprotein Cholesterol Ratio and Hematologic Indexes of Inflammation
(Wolters Kluwer Medknow Publications, 2021) Belviranli, Selman; Oltulu, Refik; Gundogan, Ali O.; Mirza, Enver; Okka, Mehmet
PURPOSE: The purpose of this study is to evaluate systemic inflammation in patients with pterygium using the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) and hematologic indexes of inflammation. METHODS: Thirty-one patients with primary pterygium and 31 age-and sex-matched healthy participants were enrolled in this retrospective study. The MHR, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, eosinophil-to-lymphocyte ratio, monocyte-to-eosinophil ratio, mean platelet volume-to-platelet count ratio, platelet distribution width, and red cell distribution width were compared between the two groups. RESULTS: There was not a statistically significant difference in terms of the MHR between the pterygium group and the control group (P = 0.693). The NLR was higher in the pterygium group than in the control group (P = 0.028). In the other hematologic indexes, there were no statistically significant differences between the two groups (P > 0.05 for all). CONCLUSION: The MHR is not associated with the presence of pterygium. An increased NLR in patients with pterygium may be an indicator of systemic inflammation.
The Frequency and Causes of Blindness in a Rural Region of Central Anatolia of Turkey
(Aves, 2019) Mirza, Enver; Mirza, Gunsu Deniz; Oltulu, Refik; Okka, Mehmet; Ozkagnici, Ahmet
Objective: This study aimed to evaluate the frequency and primary causes of blindness in adults aged 18 years and more in Sarikaya rural region of Yozgat, Turkey, to contribute to the epidemiologic information about blindness in our country. Materials and Methods: Patients who were examined between October 2016 and March 2017 in Sarikaya State Hospital, Clinic of Ophthalmology, were prospectively investigated. Demographic and ophthalmic examination data, presented visual acuities (VA), primary causes of blindness, and monocular blindness were recorded. Blindness was defined as presented visual acuities (VA) definition of World Health Organization criteria. Results: A total of 3423 participants, aged 18-96 years, were examined. Among them, 1887 participants (55%) were female and 1536 (45%) were male. The frequency of blindness was 15% (95% CI: 1.1%-2.0(%); and cataract was the primary cause of blindness (42%). Age-related macular degeneration (21%) and uncorrected refractive error (13%) were the next main causes of blindness. The frequency of monocular blindness was 4% (95% CI: 3.8%-5.2%), and cataract (27%) followed by phthisis bulbi/evisceration (13%) and glaucoma (12%) were the leading causes of monocular blindness. Conclusion: In this rural region of Central Anatolia, the primary cause of blindness and monocular blindness was an unoperated cataract. The patterns of age-specific causes of blindness are variable, but most of them are avoidable or treatable. Thus, awareness should be increased in societies, and people should be prevented from blindness with health-care programs in rural regions of developing countries.
GAPO syndrome: Four new patients with congenital glaucoma and myelinated retinal nerve fiber layer
(Wiley, 2013) Bozkurt, Banu; Yildirim, Mahmut Selman; Okka, Mehmet; Bitirgen, Gulfidan
This article reports on the ophthalmological features of four Turkish children with GAPO syndrome, a very rare autosomal recessive condition characterized by growth retardation (G), alopecia (A), pseudoanodontia (P) (failure of tooth eruption), and optic atrophy (O). The children were from two unrelated families born to consanguineous parents. They had the characteristic facial appearance of alopecia, rarefaction of eyebrows and eyelashes, frontal bossing, high forehead, midfacial hypoplasia, hypertelorism, and thickened eyelids and lips. Two children had severe end-stage glaucoma in both eyes and unilateral corneal opacity, whereas other two children had myelinated retinal nerve fiber layer; one with bilateral optic atrophy and the other one with persistent pupillary membrane in the left eye. (c) 2013 Wiley Periodicals, Inc.
Göz ovalamanın korneanın biyomekanik özelliklerine ve göz içi basıncına etkisi
(2014) Oltulu, Refik; Donbaloğlu, Meryem; Şatırtav Akdeniz, Günhal; Okka, Mehmet; Özkağnıcı, Ahmet
Amaç: Göz ovalamanın kornea biyomekaniği ve göz içi basıncına olan etkisinin değerlendirilmesi. Gereç ve Yöntem: Herhangi oküler ve sistemik bir hastalığı olmayan, 15 ile 50 yaş arası gönüllü bireylerde Oküler cevap analizörü (OCA) kullanarak Goldmann ile uyumlu göz içi basıncı (GİBg), korneanın biyomekanik özellikleri ile kompanse edilmiş GİB (GİBkk), kornea rezistans faktörü (KRF) ve kornea histerezisi (KH) değerlendirildi. Her olgudan bazal ölçüm yapıldıktan sonra 30 saniyelik bir süre boyunca kendi gözünü ovalaması istendi, ovalama sonrası mümkün olan en kısa sürede ölçüm tekrarlandı. Verilerin istatistiksel analizinde student t- testi kullanıldı. P0,05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Çalışmaya 53 olgunun 81 gözü dahil edildi. Olguların ortalama yaş ortalaması 3210,11 (15-50 yıl) idi. Ovalama öncesi ortalama KH 10,931,69 mmHg, KRF 10,821,78 mmHg, GİBg 15,763,18 mmHg ve GİBkk 15,742,69 mmHg iken ovalama sonrası KH 11,111,52 mmHg, KRF 10,541,56 mmHg, GİBg 14,323,10 mmHg ve GİBkk 14,202,77 mmHg olarak tespit edildi. KRF, GİBg ve GİBkk değerlerindeki azalma istatistiksel olarak anlamlı olup (p0,05), KHdeki değişim istatistiksel olarak anlamlı değildir (p0,05). Sonuç: Gözün ovalanmasının göz içi basınç ölçümleri ve kornea rezistans faktörü üzerine belirgin etkileri bulunmaktadır. OCA ile ölçüm alınması öncesinde ve sonuçlarının değerlendirilmesinde bu husus dikkate alınmalıdır. (Turk J Ophthalmol 2014; 44: 268-71)
Influence of Cyclopentolate Hydrochloride on Corneal Biomechanical Properties in Healthy Individuals
(Lippincott Williams & Wilkins, 2014) Oltulu, Refik; Satirtav, Gunhal; Kerimoglu, Hurkan; Zengin, Nazmi; Ozkagnici, Ahmet; Okka, Mehmet
Objective: This observational study aims to investigate the effects of cyclopentolate hydrochloride (1%) on corneal biomechanical properties, with the ocular response analyzer (ORA), in healthy individuals. Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) measurements of 36 (15 female and 21 male) healthy individuals, before and after 45 min of 1% cyclopentolate hydrochloride instillation, were performed by the ORA. Results: The mean CH and IOPcc measurements of the eyes were 10.63 +/- 1.17 mm Hg and 15.15 +/- 2.69 mm Hg, precycloplegia, and 11.09 +/- 1.32 mm Hg and 14.16 +/- 2.77 mm Hg, postcycloplegia, respectively. The differences between the precycloplegia and postcycloplegia in both measurements were statistically significant (P=0.031, P=0.016, respectively; paired t test). The mean CRF and mean IOPg measurements of the eyes were 10.40 +/- 1.16 mm Hg and 14.83 +/- 2.56 mm Hg, precycloplegia, and 10.61 +/- 1.33 mm Hg and 14.25 +/- 2.65 mm Hg, postcycloplegia, respectively. The differences between the precycloplegia and postcycloplegia measurements of the eyes were insignificant (P=0.264 and P=0.100, respectively; paired t test). Conclusions: A 1% cyclopentolate hydrochloride instillation leads to significant changes in the CH values and IOPcc measurements. This should be taken into account during the evaluation of refractive surgery candidates and in clinical conditions where ORA measurements are considered in the diagnosis and follow-up.
Klorokin tedavisinde olası retina toksisitesinin desen elektroretinografi (PERG) ile incelenmesi
(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, 1994) Okka, Mehmet
Özet verilmemiştir.
Kubbe şekilli makülalı bir olguda eşlik eden foveal seröz retina dekolmanı - Klinik seyir ve literatür özeti
(2017) Oltulu, Refik; Şatırtav, Günhal; Okka, Mehmet; Kerimoğlu, Hürkan; Mirza, Enver
Yüksek miyop hastalarda, optik koherens tomografi (OKT) ile görülen posterior stafi lom içerisindeki makülanın konveks protrüzyonu Gaucher ve arkadaşları tarafından Kubbe şekilli maküla (Dome Shaped Makula - KŞM) olarak tanımlanmıştır. KŞM'ya seröz retina dekolmanı (SRD), retina pigment epitel (RPE) düzensizlikleri veya koroidal neovaskülarizasyon (KNV) gibi görme keskinliğinin azalmasından sorumlu olan bazı komplikasyonlar eşlik edebilmektedir. Eşlik eden bu komplikasyonlara yönelik görüş birliğine varılmış bir tedavi şekli bulunmamaktadır.KŞM'ya eşlik eden SRD nedeniyle birkaç yıldır sağ gözde görme azlığı olan 51 yaşındaki kadın olgu kliniğimizde takip edilmekteydi. En iyi düzeltilmiş görme keskinliği (EİDGK) sağ gözde 6/10, sol gözde 10/10 düzeyindeydi. Yaklaşık 1 yıllık takibinde EİDGK'nin SRD'a rağmen stabil kaldığı gözlendi ancak 18. ayda subretinal sıvıda artış ve EİDGK'nde azalma meydana geldi. Bu nedenle hastanın sağ gözüne 1 ay ara ile 2 doz intravitreal Anti-VEGF (ranibizumab) enjeksiyonu yapıldı. Sonraki kontrollerinde enjeksiyona yanıt alınamadığı görüldü. Olgu ek müdahale yapılmadan yakın takip edildi. Son enjeksiyondan yaklaşık 8 ay sonra optik koherens tomografi (OKT) tetkikinde foveadaki SRD'nın spontan olarak yatıştığı ve sağ gözde EİDGK'nin 7/10 düzeyine çıktığı görüldü. SRD'nın spontan regresyonunu takiben hasta 6 ay aynı görme düzeyi ve nüks olmadan takip edildi. Bu olgu sunumunda SRD'nın eşlik ettiği komplike KŞM'lı bir hastanın yaklaşık 3 yıllık takibi sonucunda SRD'nın kendiliğinden gerilediği sürecin paylaşılması amaçlanmıştır
Mesenteric Fibromatosis Due to Malignant Hypertension: A Case Report
(2018) Mirza, Enver; Özkağnıcı, Ahmet; Nazmi, Zengin; Okka, Mehmet; Mirza, Deniz
VR is a rare condition that causes a sudden vision loss. Although VR is considered to be rare but a serious complication of surgery. Ourcase was a 64 years old woman was presented with preretinal haemorrhage including macular area in right eye secondary to VR afteran uneventful cataract surgery under general anesthesia. Her vision was counting fi ngers after the surgery. Although surgical correctionor Nd:YAG laser hyaloidotomy was available she was treated with single intravitreal TPA, intravitreal bevacizumab and 0.2cc SF6 gaseinjection. There was signifi cant reduction of premacular haemorrhage and her vision improved to 7/10 after injection on the fi nal visit.
Ocular-symptoms-related Google Search Trends during the COVID-19 Pandemic in Europe
(Springer, 2021) Mirza, Enver; Mirza, Gunsu Deniz; Belviranli, Selman; Oltulu, Refik; Okka, Mehmet
Purpose To investigate the correlation between the daily relative search volume (RSV) of keywords related to coronavirus and ocular symptoms, and the numbers of the daily coronavirus disease 2019 (COVID-19) new cases and new deaths in Europe using Google Trends (GT). Methods The RSVs of the selected keywords related to coronavirus and ocular symptoms between 24 January and 1 June 2020 in the United Kingdom, Spain, Italy, Germany and Turkey were accessed from GT. The numbers of daily COVID-19 new cases and new deaths in the same time interval in the aforementioned countries were compared with the RSVs of the keywords and terms. Results The United Kingdom, Spain, Italy, Germany, and Turkey were the most affected countries from the COVID-19 pandemic in Europe. In these countries, statistically significant and strong correlations were found between the daily RSVs of most keywords related to coronavirus and ocular symptoms, and the daily numbers of COVID-19 new cases and new deaths ranging from 0.175 to 0.807. Conclusions Ocular symptoms are not the frequent signs of COVID-19, but the ocular surface is a possible route for the transmission of COVID-19. The preliminary outcomes of this study demonstrated that there are significant correlations with the ocular symptoms and COVID-19. The news about the relation of eye and COVID-19 in the mass media may have influenced the Google internet search activity of the public for ocular symptoms.
Ön Kamara Bulanıklığının Gün İçi Değişimi
(2015) Adam, Mehmet; Okka, Mehmet; Kerimoğlu, Hürkan; Pekel, Hamiyet; Turgut Öztürk, Banu; Bozkurt, Banu; Okudan, Süleyman
Amaç: Laser flaremetre cihazı ile yapılan ön kamara bulanıklık ölçümlerin ideal zamanı ve tekrarlanabilirliğinin araştırılması. Gereç ve Yöntem: Kırk beş gönüllünün sabah saat 8.00da laser flaremetre cihazı ile ön kamara bulanıklık ölçümleri yapılmış ve bu ölçümler aynı gün saat 12.00 ve saat 16.00da tekrarlanmıştır. Bulgular: Gönüllülerin 25i (55,5) kadın ve 20si (44,5) erkekti ve ortalama yaşları 28,677,40 yıldı. Olguların oftalmolojik muayenelerini takiben alınan ortalama ön kamara bulanıklık ölçümleri sabah saat 8:00da 5,941,41 foton msn, saat 12de 5,651,45 foton/msn, saat 16.00da 5,791,20 foton/msn idi. Ölçümler arasında anlamlı bir farklılık saptanmadı (p0,08). Katılımcıların göz rengine göre yapılan alt grup analizinde de kahverengi, ela ve yeşil göz renkler arasında anlamlı bir farklılık bulunmamıştır. Korelasyon analizinde gün içinde alınan üç ölçümün de yaşla korele olduğu görülmüştür. Sonuç: Ön kamara bulanıklık ölçümlerinde sağlıklı bireylerde gün içerisinde anlamlı bir değişiklik saptanmamıştır ancak yaşla pozitif korelasyon göstermektedir. Bu nedenle gün içindeki tüm ölçümler güvenilirdir ve tekrarlanabilirliği yüksektir.
Optic disc pit with serous macular detachment in a child
(2013) Oltulu, Refik; Erşan, İsmail; Şatırtav Akdeniz, Günhal; Okka, Mehmet
Bu yazıda nadir görülen, seröz maküler dekolmanlı optik disk çukurluğu bulunan çocuk olguyu sunuyoruz. Optik disk çukurları 10000de 1den daha az görülür ve olguların %10-15inde iki taraflıdır. Doğumsal optik disk çukuru olgularının yaklaşık %50si seröz makula dekolmanı ile ilişkilidir. Uzun süre devam eden seröz dekolmanlar genellikle makülanın kistik dejenerasyonu ve alttaki retinal pigment epitelinden pigment kaybı ile ilişkilidir. Bundan dolayı, seröz maküla dekolmanı olan gözlerin çoğunda optik disk çukuru oluşumu ile birlikte göreceli olarak kötü görsel prognoz vardır. Burada seröz dekolmanlı optik disk çukuru olan çocuk olgunun değerlendirilmesinin klinik önemini vurguladık.

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