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    Backlund transformation for spacelike curves in the Minkowski space-time
    (Elsevier, 2014) Ozdemir, M.; Erdogdu, M.; Simsek, H.; Ergin, A. Aziz
    The main purpose of this paper is to construct a Backlund transformation between two spacelike curves with the same constant curvature in Minkowski space-time by considering some assumptions. Moreover, we give the relations between curvatures of these two spacelike Backlund curves.
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    Comparison of the Detection of Influenza A and B Viruses by Different Methods
    (Sage Publications Ltd, 2012) Ozdemir, M.; Yavru, S.; Baysal, B.
    OBJECTIVE: To investigate the detection of influenza viruses by three different methods. METHODS: Nasopharyngeal swabs were collected from patients with influenza symptoms and examined for influenza A and B viruses using a rapid antigen test, a multiplex polymerase chain reaction (PCR) test and a shell vial cell culture test. RESULTS: Using the shell vial cell culture test, the rapid antigen test and the multiplex PCR test in 130 patients, 31 (23.8%), 24 (18.5%) and 24 (18.5%) samples, respectively, were positive for influenza A and 10 (7.7%), nine (6.9%) and four (3.1%) samples, respectively, were positive for CHAIN REACTION TEST; influenza B. Compared with the shell vial test, the sensitivity, specificity, and positive and negative predictive values of the rapid antigen test were 77.4%, 93.3%, 80.0% and 93.1%, respectively, for influenza A, and 90.0%, 95.8%, 64.2% and 99.1%, respectively, for influenza B. The corresponding values for the multiplex PCR test were 77.4%, 95.9%, 85.7% and 93.1%, respectively, for influenza A, and 40.0%, 97.5%, 57.1% and 95.1%, respectively, for influenza B. CONCLUSIONS: The multiplex PCR test and the rapid antigen test are both effective in the detection of influenza A and B viruses.
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    Comparison of the diagnostic values in rheumatoid arthritis: Anti-CCP antibodies and other serological tests
    (Allied Acad, 2014) Dogan, M.; Kucuksarac, S.; Tufekci, O.; Feyzioglu, B.; Ozdemir, M.; Baykan, M.; Baysal, B.
    Rheumatoid arthritis (RA) is an inflammatory autoimmune disease. Early diagnosis, early and aggressive treatment are the best means of avoiding joint destruction, organ damage and disability. This prospective study was carried out to determine the relationship between RA and laboratory tests used in the diagnosis of RA. 199 patients (20 males, 179 females; mean age: 50.6 years) that were suspected to be RA were included in the study. Anti-CCP, RF, ESR, and CRP tests were performed for all patients. The patients were divided two groups named RA and non-RA according to American College of Rheumatology criteria. Of the all patients, 96(48.2%) tested as positive for anti-CCP antibodies. Of the RA patients, 93 (68.9%) were positive for anti-CCP antibodies. The positivity of anti-CCP antibodies was 4.7% (3/64) for non-RA. Sensitivity, specificity, PPV, and NPV in diagnosis of RA for anti-CCP respectively were 0.69, 0.95, 0.97, and 0.59, and for high positive anti-CCP respectively were 0.55, 1.00, 1.00, and 0.52, and for RF respectively were 0.59, 0.92, 0.94, and 0.52, and for high positive RF respectively were 0.54, 0.98, 0.99, and 0.54, and for CRP respectively were 0.73, 0.78, 0.87, and 0.57, and for ESR respectively were 0.84, 0.30, 0.72, and 0.46. Sensitivity for the diagnosis of RA could be further increased by a combination of the anti-CCP and RF tests. There was a positive correlation between anti-CCP and RF positivity (Phi=0.59537), anti-CCP and RF high positivity (Phi=0.537364), ESR and CRP (Phi=0.426544). It is concluded that performing anti-CCP test in the diagnosis of RA could be beneficial since it has high specificity and positive predictive value. If this test was performed together with RF, it may be more beneficial.