Yazar "Ozdemir, Nuriye Yildirim" seçeneğine göre listele

Listeleniyor 1 - 1 / 1
  • Küçük Resim Yok
    Öğe
    THE EFFCT OF METFORMIN USE ON PROGNOSIS IN PANCREATIC CANCER PATIENTS
    (Carbone Editore, 2014) Esbah, Onur; Eren, Tulay; Helvaci, Kaan; Guler, Tunc; Duran, Ayse Ocak; Bal, Oznur; Ozdemir, Nuriye Yildirim
    Background: Several clinical studies have shown the effect of mefformine on survival in pancreatic cancer. We aimed to evaluate whether the use of mefformin in diabetic pancreatic cancer patients provides a survival advantage or not. Methods: The data of 467 pancreatic adenocarcinoma patients diagnosed between 2003 and 2012 from five centers were analyzed, retrospectively. The groups were pancreatic cancer patients with diabetes who use metfonnin, who don't use metfornzin and non-diabetics. Results: Median overall survival was 8 months for the whole cohort, and 8 months for the group of non-diabetic patients. Overall survival was 8 months for the diabetic patients who use metfonnin whereas 10 months for the patients who do not use metformin. There was no statistically significant survival difference between the groups (p:0,76). Conclusion: Our study did not support clinical benefit of metformin in diabetic pancreatic cancer patients.