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Öğe Carbon Dots in the Detection of Pathogenic Bacteria and Viruses(Taylor & Francis Inc, 2022) Zor, Erhan; Mollarasouli, Fariba; Karadurmus, Leyla; Ozcelikay, Goksu; Ozkan, Sibel A.Bacterial and viruses pathogens are a significant hazard to human safety and health. In the imaging and detection of pathogenic microorganisms, the application of fluorescent nanoparticles is very useful. Carbon dots and quantum dots are preferred in this regard as labels, amplifiers, and/or electrode modifiers because of their outstanding features. However, precise diagnostics to identify numerous harmful bacteria simultaneously still face considerable hurdles, yet it is an inevitable issue. With the growing development of biosensors, nanoproduct-based bio-sensing has recently become one of the most promising methods for accurately identifying and quantifying various pathogens at low cost, high sensitivity, and selectivity, with time savings. The most recent applications of carbon dots in optical and electrochemical-based sensors are discussed in this review, along with some examples of pathogen sensors.Öğe Magnetic nanoparticles in developing electrochemical sensors for pharmaceutical and biomedical applications(Elsevier, 2021) Mollarasouli, Fariba; Zor, Erhan; Ozcelikay, Goksu; Ozkan, Sibel A.A revolutionary impact on the pharmaceutical and biomedical applications has been arisen in the few years to come as a result of the advances made in magnetic nanoparticles (MNPs) research. The use of MNPs opens wide opportunities in diagnostics, drug and gene delivery, in vivo imaging, magnetic separation, and hyperthermia therapy, etc. Besides, their possible integration in sensors makes them an ideal essential element of innovative pharmaceutical and biomedical applications. Nowadays, MNPs-based electrochemical sensors have attracted great attention to pharmaceutical and biomedical applications owing to their high sensitivity, stability. Selectivity towards the target as well as their simplicity of manufacture. Therefore, this review focus on recent advances with cutting-edge approaches dealing with the synthesis, design, and advantageous analytical performance of MNPs in the electrochemical sensors utilized for pharmaceutical and biomedical applications between 2015 and 2020. The challenges existing in this research area and some potential strategies/future perspectives for the rational design of electrochemical sensors are also outlined.Öğe Trends in on-site removal, treatment, and sensitive assay of common pharmaceuticals in surface waters(Elsevier Sci Ltd, 2022) Kaya, S. Irem; Gumus, Eda; Cetinkaya, Ahmet; Zor, Erhan; Ozkan, Sibel A.Global human population growth, advances in the healthcare sectors, investments in research, and aging societies in industrialized countries have led to a substantial increase in the consumption of pharmaceuticals. Simultaneously, advances in analytical methods and technology have allowed the treatment of pharmaceutical substances before release to aquatic environment and detection at low concentration values. Considering the importance of pharmaceuticals as one emerging group of environmental contaminants, this review provides the current state of knowledge on the technology and trends in on-site treatment and detection of common pharmaceuticals in surface waters. We discuss the general aspects and the materials used for constructing technology with selected studies between 2017 and 2021. Additionally, we explore how these materials and technologies help to develop simple but efficient treatment and detection methods for pharmaceuticals in surface waters. Finally, we discuss the future outlooks.(c) 2022 Elsevier B.V. All rights reserved.
