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    The prevalence of fibromyalgia and its relation with headache characteristics in episodic migraine
    (Springer London Ltd, 2013) Kucuksen, Sami; Genc, Emine; Yilmaz, Halim; Salli, Ali; Gezer, Ilknur Albayrak; Karahan, Ali Yavuz; Salbas, Ender
    The objective of this study was to assess the prevalence of fibromyalgia (FM) in patients with episodic migraine and to evaluate the relationship between migraine characteristics and FM. One hundred and eighteen consecutive patients (mean age = 38 years, 75 % women) fulfilling the International Classification of Headache Disorders-II criteria for migraine with (n = 22) and without (n = 96) aura from an outpatient headache clinic of a university hospital were evaluated. The diagnosis of FM was made based on the 1990 American College of Rheumatology classification criteria. Participants completed some self-administered questionnaires ascertaining sociodemographics, headache severity, frequency and duration, headache-related disability (Headache Impact Test [HIT-6]) and Migraine Disability Assessment Scale, widespread musculoskeletal pain (visual analog scale), depression (Beck depression inventory), anxiety (Beck anxiety inventory), sleep quality (Pittsburgh Sleep Quality Index), fatigue (Multidimensional Assessment of Fatigue), and quality of life (Short Form-36 Health Survey [SF-36]). In patients with FM, the tender point count and the Fibromyalgia Impact Questionnaire were employed. FM was diagnosed in 37 (31.4 %) of the patients. FM comorbidity was equally distributed across patients with and without aura. Severity of migraine headache, HIT-6, and anxiety were especially associated with FM comorbidity. Patients suffering from migraine plus FM reported lower scores on all items of the SF-36. This study indicates that the assessment and management of coexisting FM should be taken into account in the assessment and management of migraine, particularly when headache is severe or patients suffer from widespread musculoskeletal pain.
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    Relationship between prevalence and severity of restless legs syndrome and anemia in patients with systemic lupus erythematosus
    (Wiley, 2017) Kucuk, Adem; Uslu, Ali Ugur; Yilmaz, Ramazan; Salbas, Ender; Solak, Yalcin; Tunc, Recep
    Aim: Our aim was to evaluate the relationship between the prevalence and severity of restless legs syndrome (RLS) and the anemia in patients with systemic lupus erythematosus (SLE). Methods: This was a case-control study which was conducted at the rheumatology clinic of a university affiliated hospital, including 62 patients with SLE and 62 age-and sex-matched healthy controls. The patients were divided into two groups in terms of their hemoglobin levels. The criterion for anemia was hemoglobin level lower than 12 g/dL in females and 13 g/dL in males. Results: Nineteen patients (30.6%) in the patient group were diagnosed with RLS, and International RLS Study Group Rating Scale (IRLSSG-RS) score was 10.7 +/- 9.5 (median: 10.0 [range: 0.0-30.0]). Three subjects (4.8%) in the control group had RLS, and the IRLSSG-RS score was 0.7 +/- 3.3 (median: 0.0 [range: 0.0-18.0]). The prevalence of RLS and the IRLSSG-RS score were higher in the patient group than those in the control group (P < 0.001). Ten SLE patients (50%) with anemia had RLS, and their IRLSSG-RS score was 14.5 +/- 9.9 (median: 21.0 [range: 11.0-30.0]). Nine SLE patients (21.4%) without anemia had RLS and their IRLSSG-RS was 9.0 +/- 8.9 (median: 21.0 [range: 11.0-24.0]). Significant differences were present in the prevalence of RLS and the IRLSSG-RS score between SLE patients with and without anemia (P = 0.024, P = 0.044, respectively). Conclusion: The present study demonstrated that the prevalence of RLS was higher in patients with SLE than that of the normal population. Results of this study also suggested that anemia was associated with higher frequency of and more severe RLS in patients with lupus.
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    Sever Disease: An Important Cause of Heel Pain in Children; Case Report
    (Galenos Yayincilik, 2014) Karahan, Yavuz Ali; Salbas, Ender; Tekin, Levent; Yasar, Ozan; Kucuk, Adem
    Calcaneal apophysitis is the most common cause of heel pain in children and described as Sever disease. Sever disease typically occurs during a growth spurt and at the beginning of a new sport season. The disease is associated with only the heel pain in children and does not occur after puberty. In a child presenting with heel pain, the differential diagnosis may include achilles tendonitis, retrocalcaneal bursitis, calcaneal stress fractures, calcaneal cysts, osteomyelitis, and plantar fasciitis. Other reasons included in the differential diagnosis can be ruled out with a well-performed clinical evaluation. Although Sever disease is a common clinical entity there are quite a few documentations about this disease in national and international literature. In this article we aimed to present a 12-year-old male patient who presented with complaints of bilateral heel pain and limping, and to evaluate signs and symptoms, diagnostic approaches and treatment protocols of the disease in the light of current literature.