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Öğe Early Surgical Results of Patent Ductus Arteriosus in Premature Infants(Gazi Univ, Fac Med, 2018) Altinbas, Ozgur; Ozer, Abdullah; Isik, Mehmet; Sarigul, Ali; Ege, ErdalObjective:Our aim is to evaluate the closure of patent ductus arteriosus through surgery at an early stage, commonly seen in premature infants and a leading cause of left-to-right shunt and mortality/morbidity, as a safe modality to prevent complications that may develop in postnatal preiod in patients with bronchopulmonary displasia or respiratory distress syndrome followed up in mechanical ventilation, and whose ductus arteriosus can not be closed despite medical treatment. Material and Methods:Thirty two cases of patent ductus arteriosus with premature birth history and no additional cardiac pathology, performed in the Department of Cardiovascular Medical School, Necmettin Erbakan University between 2006-2015 were included into the study. Results:Of the 32 patients, 14 (43,7%) were females and 18 (56,3%) were males. The most frequently seen preoperative disorder was respiratory distress syndrome(n=20). Twenty-two (68%) of the patients were following as intubated in newborn intensive care unit. Surgical procedure was performed in patients whose ductus were not closed via medical treatmentorin whom medical treatment was contraindicated for problems such as intracranial hemorrhage, renal failure or thrombocytopenia. Excitus rate was 15,6% (n=5) in our series. Removal time of mechanical ventilation was average 6,2 days. Postoperative echocardiography showed no recurrence of patent ductus arteriosus. Conclusion:Prevention of postnatal mortality and morbidity due to patent ductus arteriosus in premature infants can be achieved by early surgical closure during postnatal early period before secondary organ failure due to shunting develops and infants with critical general status-dependent on mechanical vantilation-,and for whom medical treatment is unsuccessful.Öğe Early Surgical Results of Patent Ductus Arteriosus in Premature Infants(Gazi Univ, Fac Med, 2018) Altinbas, Ozgur; Ozer, Abdullah; Isik, Mehmet; Sarigul, Ali; Ege, ErdalObjective:Our aim is to evaluate the closure of patent ductus arteriosus through surgery at an early stage, commonly seen in premature infants and a leading cause of left-to-right shunt and mortality/morbidity, as a safe modality to prevent complications that may develop in postnatal preiod in patients with bronchopulmonary displasia or respiratory distress syndrome followed up in mechanical ventilation, and whose ductus arteriosus can not be closed despite medical treatment. Material and Methods:Thirty two cases of patent ductus arteriosus with premature birth history and no additional cardiac pathology, performed in the Department of Cardiovascular Medical School, Necmettin Erbakan University between 2006-2015 were included into the study. Results:Of the 32 patients, 14 (43,7%) were females and 18 (56,3%) were males. The most frequently seen preoperative disorder was respiratory distress syndrome(n=20). Twenty-two (68%) of the patients were following as intubated in newborn intensive care unit. Surgical procedure was performed in patients whose ductus were not closed via medical treatmentorin whom medical treatment was contraindicated for problems such as intracranial hemorrhage, renal failure or thrombocytopenia. Excitus rate was 15,6% (n=5) in our series. Removal time of mechanical ventilation was average 6,2 days. Postoperative echocardiography showed no recurrence of patent ductus arteriosus. Conclusion:Prevention of postnatal mortality and morbidity due to patent ductus arteriosus in premature infants can be achieved by early surgical closure during postnatal early period before secondary organ failure due to shunting develops and infants with critical general status-dependent on mechanical vantilation-,and for whom medical treatment is unsuccessful.Öğe Effects of albumin and synthetic polypeptide-coated oxygenators on IL-1, IL-2, IL-6, and IL-10 in open heart surgery(Elsevier Singapore Pte Ltd, 2014) Simsek, Erdal; Karapinar, Kasim; Bugra, Onursal; Ulus, Ahmet Tulga; Sarigul, AliBackground: In this study, we have tried to demonstrate the effects of coating style used in oxygenators on various hematologic and clinical parameters. Materials and methods: Twenty-seven patients were included in the study, who had undergone operations because of elective coronary artery disease. Albumin-coated oxygenator was used in Group I. In Group II, a synthetic polypeptide-coated oxygenator was used. C1-inhib (complement), C3c, C4, interleukins (IL-1 beta, IL2, IL-6, IL-10), and tumor necrosis factor alpha (THE-a) levels were examined at four different time intervals. Hemoglobin, hematocrit, leukocyte and platelet counts, drainage, and transfused blood volumes were analyzed. Results: Albumin levels were significantly lower in Group I than those in Group II 5 minutes after the removal of the cross-clamp. Twenty-four hours after the surgery, Group I patients also had a significantly higher white blood cell count compared to Group II patients. THE-a levels in Group I were always expressed in considerably higher amounts than those in Group II. IL-6 levels were significantly higher in Group I, but IL-10 levels were observed to be higher in Group II (p < 0.05). Conclusion: Synthetic polypeptide-coated advanced technology, which employed oxygenators, had an important attenuator effect on acute phase reactants and also on the inflammatory response. Copyright (C) 2013, Asian Surgical Association. Published by Elsevier Taiwan LLC. All rights reserved.Öğe Post-Spinal a Rare Complication and Treatment: Tinnitus and Epidural Blood Patch(Aves, 2015) Sarkilar, Gamze; Reisli, Ruhiye; Saritas, Tuba Berra; Gok, Funda; Sarigul, Ali; Otelcioglu, Seref[Abstract Not Availabe]Öğe Prevalence of and risk factors for early postoperative arrhythmia in children after cardiac surgery(Wiley, 2014) Alp, Hayrullah; Narin, Cuneyt; Baysal, Tamer; Sarigul, Ali[Abstract Not Availabe]Öğe Successful pericardiectomy in Hennekam syndrome(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2013) Karatas, Zehra; Karaarslan, Sevim; Alp, Hayrullah; Sarigul, Ali; Baysal, TamerHennekam syndrome is an autosomal recessive disorder, characterized by lymphangiectasia in internal organs with lymphedema. Pleural or pericardial effusions may present with lymphedema on extremities in the course of the disease. Although a poor long-chain fatty diet is given for treatment, its success rate is low. In this article, we report the results of a successful pericardiectomy performed on a 21-month-old boy who was diagnosed with Hennekam syndrome.Öğe Sutureless Aortic Valve Replacement with Minimally Invasive Method: Case Report(Gazi Univ, Fac Med, 2016) Ozer, Abdullah; Ugurlu, Okan; Sarkilar, Gamze; Ege, Erdal; Sarigul, AliTwo patients accepted to our clinic with the diagnosis of aortic stenosis were considered to have high risk for classic surgery and were planned to undergo aortic valve replacement by a minimally invasive procedure with anterior thoracotomy. We believe that, the minimally invasive procedure is much more convenient than classical surgical techniques in patients having high risk for severe aortic stenosis.Öğe Sutureless Aortic Valve Replacement with Minimally Invasive Method: Case Report(Gazi Univ, Fac Med, 2016) Ozer, Abdullah; Ugurlu, Okan; Sarkilar, Gamze; Ege, Erdal; Sarigul, AliTwo patients accepted to our clinic with the diagnosis of aortic stenosis were considered to have high risk for classic surgery and were planned to undergo aortic valve replacement by a minimally invasive procedure with anterior thoracotomy. We believe that, the minimally invasive procedure is much more convenient than classical surgical techniques in patients having high risk for severe aortic stenosis.