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Öğe Evaluation of D-Dimer and Neutrophil/Lymphocyte Ratios of COVID-19 Patients Whom Applied to Karapinar State Hospital(Marmara Univ, Inst Health Sciences, 2022) Kader, Saadet; Akdag, Turan; Sariyildiz, Levent; Ozel, ZeynepObjective: The epidemic which caused by the SARS-CoV-2 virus were defined as COVID-19) and declared as a global pandemic by the World Health Organization (WHO) on March, 2020. Nowadays, many biochemical parameters related to the diagnosis and prognosis of COVID-19 are being investigated. Therefore, we aimed to evaluate D-dimer and neutrophil/lymphocyte ratios (NLR) of COVID-19 patients whom applied to Karapinar State Hospital. Methods: Patients which consisted of 2523, whom diagnosed with COVID-19 between 11 March 2019 and 29 July 2021 at Karapinar State Hospital were included in the study. Age, gender and social history of the patients were recorded. From the results, the relationships between D-dimer and hemogram were evaluated. Results: There was a high correlation between the variables HCT and HGB, PLT and PCT, NEUT# and WBC, and MCH and MCV (r=0.981, r=0.944, r=0.923, r=0.925). In addition, there was a high correlation between RBC and HCT and between RBC and HGB variables (r=0.852, r=0.795). There was a moderate correlation between WBC and MO#, MCHC and MCH, PDW and MPV (r=0.562, r=0.639, r=0.64). All the relationships between these variables were positive, and the value of the correlated parameter increases linearly by unit. Also, the highest positive relationships were between HCT and HGB, PLT and PCT, NEUT# and WBC, MCH and MCV. Moreover, D-dimer and NLR were not correlated (r= - 0.015, p=0.49). Conclusion: In the study, no correlation was observed between D-dimer and neutrophil/lymphocyte ratios of COVID-19 patients. So, more comprehensive and further studies are needed to clarify these results.Öğe Investigation of Some Hematological and Biochemical Parameters in Pregnancy and Early Puerperium(Derman Medical Publ, 2013) Sariyildiz, Levent; Akdag, Turan; Tiftik, Ali MuhtarAim and Material and Method: The aim of the study was investigate some biochemical parameters in pregnancy and after birth. In this study, we determined the levels of serum Fe, TIBC, Ca, Mg, triglyceride, total cholesterol, and whole blood WBC, RBC, HCT, HGB in twenty pregnant women whose age ranges were 20-35 yr. The samples were collected before the birth for three times (during three trimester) and after the forty days of birth for only once. Results: Our findings show that levels of triglyceride, total cholesterol and RBC statistically increased (p<0.01) in pregnant women from the first trimester to the birth. Levels of RBC statistically (p<0.01) decreased more in the forth day after the birth than the first trimester of pregnancy. Although we determined statiscally important low levels of triglyceride, total cholesterol after the birth, we also concluded that those low levels were higher than those at the beginning of pregnancy. Although our findings showed statistically important low levels of Fe, TIBC, Ca and Mg since the first trimester during pregnancy, Ca and Mg levels increased more in the forth day after birth than those at the beginning of pregnancy. Furthermore, Fe levels showed an important increase (p<0.05) but did not reach the levels that were at the beginning of pregnancy. In the second trimester an increase and in the third trimester, in the forth day of the birth decreases in TIBC levels were determined. At the end of the pregnancy, the lowest levels of TIBC were determined. We concluded statistically important (p<0.01) low levels of RBC, HGB and HCT in the second trimester. However, it reached the levels that were at the beginning of pregnancy in the third trimester. Whereas the levels of RBC and HGB in the forth day of the birth were higher than (p<0.01) those at the first trimester, hematocrit levels were similar to the level that were at the beginning of pregnancy. Discussion: Metabolic change that occur during pregnancy affect the health of both mother and fetus. Before and during pregnancy routine investigation and monitoring of the biochemical parameters will be important for prevention of deficiency for the healthy pregnancy and fetus.Öğe A New Predictor AMH (anti-mullerian hormone) to Determining Ovarian Reserve and Menoposual Aging in the Women(Derman Medical Publ, 2013) Sariyildiz, Levent; Akdag, TuranAnti-mullerian hormone (AMH), also termed Mullerian inhibiting substance (MIS), is produced in ovary by granulose cells and known as a member of the TGF-beta superfamily. The researchers imply that AMH is associated with the various growth factors in development and growth of ovarian follicles, furthermore is exhibited the features of other TGF-beta family members. AMH has a critical importance in reproductive age of women. Certain standardization has not yet been developed in determing the ovarian reserve. Recent findings reveal the importance of AMH in determining ovary function and, highlight the importance of AMH than FSH.Öğe Some Hematological and Metabolic Changes Observed in Pregnancy(Derman Medical Publ, 2013) Sariyildiz, Levent; Akdag, TuranDuring healthy pregnancy, distinct physiological changes occur in the blood composition These changes can be perceived as possible development for appropriate environment to maternal and infant health and possible bleeding at the birth. Body adipose storages increases with food uptake in the half period in pregnancy, In the last period of gestation especially in cases of pro long fasting, destruction of this stored mass adipose IS necessary. Some anomalies may occur in pregnancy. if taken food and necessary appropriate materials are insufficient. These abnormal conditions develop depending on lack of calcium, phoshpate, iron and vitamins.
