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Öğe The Characteristics of Patients Returning to Hemodialysis due to Nonfunctioning Graft in Turkey(Wolters Kluwer Medknow Publications, 2019) Altun, Ilkem; Selcuk, N. Yilmaz; Baloglu, Ismail; Turkmen, Kultigin; Tonbul, H. ZekiRenal transplantation is the most effective treatment modality for end-stage renal failure. According to the Ministry of Health Organ Transplant Registration System, despite the presence of 14,936 renal transplant recipients in Turkey, there are not enough data about the prognosis of these patients. Therefore, we aimed to ascertain the rate of patients returning to hemodialysis (HD) due to nonfunctioning graft in our country. One thousand four hundred and ninety-eight (males: 826, females: 672) HD patients who undergo HD at 22 HD centers in total, from different geographical regions to represent our country were examined retrospectively. The informations were obtained from patient registry files and anamnesis which were in HD centers. The number of patients returning to HD due to the loss of graft function was 77 (males: 56, females: 21). Eleven of the patients had transplantation from cadavers (14%) and 66 from living donors (86%). Prevelance of patients, who return to HD after the failure of renal transplantation, between HD patients was 5.1. The mean duration of return to HD after renal transplantation was 6.7 +/- 5.9 years for all patients. There was no significant difference in the duration without HD after transplantation between two groups when cadaveric and living donor transplants were compared (P = 0.759). There was no statistically significant difference in duration without HD after transplantation between patients receiving HD treatment before transplantation and preemptive transplant (P = 0.212). The prevelance of patients, who return to HD due to nonfunctioning graft among HD patients was 5.1. The duration without HD were similar after transplantation from both cadavers and living donors. The duration without HD was found longer among those who were operated before 2000.Öğe Evaluation of Hemodialysis Adequacy: Correlation between Kt/Vurea and Other Methods(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2019) Baloglu, Ismail; Selcuk, N. Yilmaz; Evran, Hatice; Tonbul, Halil Zeki; Turkmen, KultiginObjective: Uremic toxins must be adequately cleared to reduce mortality and morbidity in chronic hemodialysis patients. The second-generation Daugirdas formula (D) is recommended for measurement of hemodialysis adequacy according to the guidelines specified by Kidney Disease Outcomes Quality Initiative (KDOQI) in guidelines. We aimed to compare the Kt/V ratio obtained by D (D Kt/V) to the urea reduction ratio (URR) and the Online Clearance Monitor (OCM (R)). Materials and Methods: Our research is across-sectional study on 48 patients who are on maintenance hemodialysis (HD). A total of 1990 HD sessions were performed 3 times a week for 4 hours each day for 3 months. Ionic dialysate was measured by OCM module of the Fresenius 4008 C machine. In the same HD session, URR and Kt/V ratio were calculated using a single-pool Daugirdas formula. Results: This study included 48 (Male: 24, Female: 24) adult chronic HD patients. Mean age of the patients was 54.5 +/- 18.1 years (16-81 years). Mean Kt/V value was found be higher when calculated using D formula (1.54 +/- 0.36) than what was measured by ionic dialysate (1.37 +/- 0.32) (p<0.0001). Comparison between D Kt/V and URR showed a statistically relevant significance (p<0.0001, r=0.92). Mean ultrafiltration (UF) was 1521 +/- 1054 milliliters per session. When D Kt/V was calculated without UF, the mean Kt/V value measured by ionic dialysate was not different from D Kt/V without considering UF (1.43 +/- 0.32) (p=0.101). In spite of the fact that URR was positively correlated with two formulas, the relationship between D Kt/V and URR was statistically more significant. Conclusion: In our study, Kt/V calculated with D formula was higher than Kt/V measured by OCM. If the Daugirdas formula was calculated without considering UF, the Kt/V found by both methods was similar. Even though the URR correlated with two formulas, the relationship between D Kt/V and URR was statistically more significant. OMC is a practical tool that can help us to assess hemodialysis adequacy.Öğe EVALUATION OF LONG TERM THIRST DUE TO RAMADAN FASTING IN TERMS OF ACUTE KIDNEY INJURY(Oxford Univ Press, 2017) Pektas, Fatih; Tonbul, H. Zeki; Baloglu, Ismail; Turkmen, Kultigin; Selcuk, N. Yilmaz; Erdur, F. Mehmet[Abstract Not Availabe]Öğe FGF-23 AND KLOTHO LEVELS IN RENAL TRANSPLANT PATIENTS AND COMPARISON WITH HEMODIALYSIS PATIENTS(Oxford Univ Press, 2017) Baloglu, Ismail; Turkmen, Kultigin; Selcuk, N. Yilmaz; Tonbul, H. Zeki; Erdur, F. Mehmet[Abstract Not Availabe]Öğe The relationship between coronary artery calcium scores and left atrium size in hemodialysis patients(Springer, 2017) Baloglu, Ismail; Turkmen, Kultigin; Tonbul, H. Zeki; Selcuk, N. YilmazHemodialysis patients have extremely increased cardiovascular mortality. The coronary artery calcification score (CACS) in uremic patients receiving hemodialysis reflects the severity of atherosclerotic vascular disease and predicts the cardiovascular events. In cardiac conditions, left atrial (LA) size has a prognostic importance. In this study, relationship between coronary artery calcification and left atrial size was investigated. This was a cross-sectional study involving 32 hemodialysis patients (16 females, 16 males; mean age, 52.4 +/- 14.1 years) receiving HD for 6 months. Coronary artery calcium scoring was performed by a 16-MDCT scanner, and CACS was calculated by Agatston score. A calcification was defined as a minimum of two adjacent pixels (> 0.52 mm(2)) with a density over 130 Hounsfield units. Patients were divided into two subgroups (group 1: CACS 45.85, n = 16 and group 2: CACS > 45.85, n = 16) according to median CACS value. Mean CACS value of 32 hemodialysis patients was 245.57 +/- 373.91. LA size was significantly higher in patients with CACS > 45.85 (group 2) than in patients with CACS 45.85 (group 1). In the bivariate correlation analysis, total CACS was positively correlated with left atrium size (r = 0.47, p = 0.006). Total CACS was positively correlated with age (r = 0.43, p = 0.014). LA size was positively correlated with diastolic blood pressure (r = 0.42, p = 0.016) and negatively correlated with ejection fraction (r = -0.42, p = 0.016). The clinical parameters such as BMI, duration of dialysis, blood pressure, ejection fraction, serum levels of calcium, phosphorus, uric acid, albumin, CRP, triglyceride, cholesterol, hemoglobin and ferritin were not independently associated with total CACS. We found a positive relationship between the CACS and LA size measured by echocardiography in hemodialysis patients. Therefore; echocardiography, which is cheaper and non-invasive than tomographic examinations, might be considered for the risk stratification of coronary artery disease in hemodialysis patients.Öğe THE RELATIONSHIP BETWEEN CORONARY ARTERY CALCIUM SCORES AND LEFT ATRIUM SIZE IN HEMODIALYSIS PATIENTS(Oxford Univ Press, 2017) Baloglu, Ismail; Turkmen, Kultigin; Tonbul, H. Zeki; Selcuk, N. Yilmaz[Abstract Not Availabe]