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Öğe CHA2DS2-VASc and HAS-BLED scores are not associated with cardiac defibrillators therapies(Czech Soc Cardiology & Czech Soc Cardiovascular Surgery, 2021) Alsancak, Yakup; Sari, Hasan; Gurbuz, Ahmet Seyfeddin; Sertdemir, Ahmet Lutfi; Aribas, Alpay; Soylu, AhmetAim: The CHA(2)DS(2)-VASc (heart failure, hypertension, age >75, diabetes mellitus, stroke history, vascular disease, 65-74 age range, gender) and HAS-BLED (hypertension, abnormal renal/liver function, stroke, bleeding history, labile INR, elderly, drugs/alcohol) are scoring system for using to estimate stroke and bleeding development in cases with atrial fibrillation. We aim to evaluate the relationship between the implantable cardioverter defibrillator (ICD) therapies and CHAIDSi-VASc and HAS-BLED scores. Methods: 398 patients were included in this retrospective study after reviewing the data of the patients above the age of 18 who had ICD implantation for any reason between 2014-2019 and who were found to have at least two pacemaker check-ups with 6-month intervals. CHA(2)DS(2)-VASc and HAS-BLED scores were calculated during the device implantation and last control visit date. Results: 148 of the patients received ICD therapy (appropriate shock [n = 1181 and in appropriate therapy In = 301) and 250 of them did not receive any therapy. It was observed that the CHA(2)DS(2)-VASc and HAS-BLED scores were similar in the groups receiving and not receiving therapy (respectively, p = 0.64 and p = 0.60). CHA(2)DS(2)-VASc and HAS-BLED scores were similar in patients with appropriate shock or not (respectively p = 0.89 and p = 0.85) with median follow-up period 5.5 years. Multivariate regression analysis showed that reduced ejection fraction, presence of single-chamber ICD, lapsing of a long time after the implantation were independent risk factors for ICD device therapies (p < 0.05). Conclusions: CHA(2)DS(2)-VASc and HAS-BLED scores are not associated with device-based ICD therapies.Öğe Corelation Between the 24-Hour Urine Aldosterone Levels and Atrial Electromechanical Conduction Time(Elsevier Science Inc, 2013) Soylu, Ahmet; Alibasic, Hayrudin; Yildirim, Elif; Toker, Aysun; Erdogan, Halil Ibrahim; Duzenli, Mehmet Akif; Tokac, Mehmet[Abstract Not Availabe]Öğe Esansiyel hipertansif hastalarda sol ventrikül hipertrofisinin gelişimine ve sol ventrikül geometrik paternlerine aldosteronun etkisi(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, 2003) Soylu, Ahmet; Temizhan, AhmetSol ventrikül hipertrofisi, hipertansif hastalardaki kardiyovasküler mortalite ve morbidite için bağımsız bir risk faktörüdür ve bu nedenle de sol ventriküldeki büyümeyi başlatan faktörlerin tespit edilmesi çok önemlidir. Bu çalışmada, diğer faktörlerden bağımsız olarak, aldosteronun esansiyel hipertansiyonu olan hastalarda gelişen sol ventrikül hipertrofîsiyle ve sol ventrikülün farklı geometrik şekilleriyle olan ilişkisini araştırmayı amaçladık. Bu amaçla çalışmaya alınan esansiyel hipertansiyonlu 44'ü kadın (yaş ortalaması 51±8 yıl), 39'u erkek (yaş ortalaması 57+10 yıl) toplam 83 hastadan 32'sinde ekokardiyografik sol ventrikül hipertrofisi tespit edildi. Ayrıca hastalar sol ventrikül geometrik şekillenmesine göre gruplandırıldığmda ise, 18 hastanın konsantrik sol ventrikül hipertrofisine, 14 hastanın eksantrik sol ventrikül hipertrofisine, 17 hastanın konsantrik remodelinge ve 34 hastanın ise normal sol ventrikül geometrisine sahip olduğu görüldü. Bütün hastalardan kullanmakta oldukları antihipertansif ilaçlar iki hafta süre ile kesildikten sonra plazma aldosteron düzeyi ve renin aktivitesi ölçümü yapıldı. Plazma aldosteron düzeyi sol ventrikül hipertrofisi olan hastalarda olmayanlara kıyasla istatistiksel anlamlı olarak daha yüksek tespit edilirken (sırasıyla 9,92+6,34ng/dl ve 5,83±3,5ng/dl, p<0.01), plazma renin aktivitesindeki fark istatistiksel anlamlı değildi. Sol ventrikül geometrik şekillenmesine göre gruplar karşılaştırıldığında ise sol ventrikül konsantrik hipertrofisi bulunan hastaların plazma aldosteron düzeylerinin (10,3±5,6ng/dl), normal geometriye sahip hastalardan (5,97±3,9ng/dl) ve konsantrik remodelingi olan hastalardan (5,54±3,2ng/dl) istatistiksel olarak anlamlı yüksek olduğu görüldü (sırasıyla p=0.018, p=0.027). Plazma renin aktiviteleri arasında istatistiksel anlamlı fark yoktu. Sonuç olarak; esansiyel hipertansif hastalarda plazma aldosteron düzeylerinin diğer faktörlerden bağımsız olarak sol ventrikül hipertrofisi ile, özellikle de konsantrik sol ventrikül hipertrofisi ile ilişkili olduğunu düşünmekteyiz.Öğe Rare Case of Coronary Anomaly, Overview of Hypertrophic Cardiomyopathy with A Different Presentation(Emergency Medicine Physicians Assoc Turkey, 2023) Oktay, Irem; Kesriklioglu, Serhat; Soylu, AhmetCoronary artery anomalies are uncommon cardiac diseases. It is mostly detected incidentally in the adult population as well as being usually asymptomatic. Although its prevalence is low, its association with atherosclerosis, arrhythmias, and hypertrophic cardiomyopathy is important for sudden cardiac death. According to the literature, the association of hypertrophic cardiomyopathy with the coronary anomaly is rare. No case of hypertrophic cardiomyopathy accompanied by the absence of the left anterior descending artery has been reported. Therefore our case is special and valuable..Öğe Relation of 24-Hour Urinary Aldosterone Levels with Nondipper Blood Pressure Pattern in Normotensive Individuals(Elsevier Science Inc, 2013) Soylu, Ahmet; Alibasic, Hayrudin; Yildirim, Elif; Toker, Aysun; Erdogan, Halil Ibrahim; Duzenli, Mehmet Akif; Tokac, Mehmet[Abstract Not Availabe]Öğe The relationship of systemic and pulmonary arterial parameters with HFpEF scores (H2FPEF, HFA-PEFF) and diastolic dysfunction parameters in heart failure patients with preserved ejection fraction(Wiley, 2024) Yavuz, Yunus Emre; Soylu, Ahmet; Gurbuz, Ahmet SeyfettinObjective: We aimed to show the relationship between pulmonary pulse wave transit time (pPTT), pulmonary artery stiffness (PAS), and aortic stiffness parameters measured by non-invasive methods, HFpEF patients, and HFpEF scores (H2FPEF, HFA-PEFF).Method: A total of 101 patients were included in our study, 52 of whom were HFpEF patients and 49 were control groups without heart failure. Echocardiographic parameters for PAS and pPTT were calculated, along with diastolic parameters that support the diagnosis of HFpEF. Aortic stiffness was assessed using a PWA monitor. Demographic features, laboratory findings, aortic stiffness parameters, and echocardiographic findings including pulmonary artery parameters were compared with the control group.Results: PAS, pPTT, PWV were significantly higher in the HFpEF group than in the control group (p < 0.001). PAS and pPTT correlated positively with HFpEF scores. In linear regression analysis for PAS, a directly positive correlation was found between E/e' and PAS, independent of aortic stiffness.Conclusion: These parameters can be used as a predictive value in the diagnosis process of patients with suspected HFpEF. A significant relationship between PAS and ventricular stiffness (E/e') was shown independently of aortic stiffness.
